X-linked recessive MCQ 9+

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• Given a husband with haemophilia and his unaffected wife
  ক

  None of their daughter will be affected

  খ

  All of their daughters will carry the haemophilic gene

  গ

  A daughter with Turner’s syndrome may also have haemophilia

  ঘ

  His maternal grandfather could have had haemophilia

  ঙ

  All of his sisters will be carriers
• The following statements are correct regarding X- linked recessive trait
  ক

  The gene responsible for the condition is transmitted from an affected man to all his daughters.

  খ

  The gene is never transmitted directly from father to son.

  গ

  Normal offspring may be produced if mating occurs between an affected male and a carrier female.

  ঘ

  The trait manifests only in males.

  ঙ

  A carrier female will transmit the condition to 25% of her sons.
• X-linked disorders are
  ক

  Duchenne muscular dystrophy

  খ

  Becker dystrophy

  গ

  Emery- dreifuss dystrophy

  ঘ

  Myotonic dystrophy

  ঙ

  Fascioscapulohumoral dystrophy
• X-linked recessive disorders are
  ক

  Diabetes insipidus

  খ

  Haemophilia

  গ

  Duchenne muscular dystrophy

  ঘ

  Alkaptonuria

  ঙ

  Polycystic kidney disease
• X- linked disorders are
  ক

  Hemophilia

  খ

  Duchene muscular dystrophy

  গ

  Cystic fibrosis

  ঘ

  WILSON disease

  ঙ

  Acrodermatitis enteropathica
• X linked recessive traits are
  ক

  Lesch-Nyhan syndrome

  খ

  Hemophilia

  গ

  Phenylketonuria

  ঘ

  Galactosemia

  ঙ

  Tay Sachs disease
• Single gene inherited X-linked disorder/s is/are
  ক

  Duchenne muscular dystrophy

  খ

  Fragile X syndrome

  গ

  Neurofibromatosis

  ঘ

  Sickle cell anaemia

  ঙ

  Myotonic dystrophy
• Examples of X-linked disorders are
  ক

  Fragile X syndrome

  খ

  Ducchene muscular dystrophy

  গ

  Hemophilia A

  ঘ

  Neurofibromatosis

  ঙ

  Familial polyposis coli
• The characteristics of X-Linked inheritance diseases is/are
  ক

  Male are affected

  খ

  Carrier woman have 50% chance for the normal child

  গ

  Female carrier are affected

  ঘ

  Affected male have 25% risk of affected son

  ঙ

  Carrier woman have 25% risk of carrier daughter