Transdermal Drug Delivery Systems MCQ

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• Which of the following is false for monolithic devices?
  ক

  The drug used for these devices has large therapeutic indices

  খ

  There are three categories of matrix devices

  গ

  1st type has the drug dissolved in the polymer matrix

  ঘ

  2nd type has drug dispersed
• Which of the following is true for monolithic devices?
  ক

  These devices are used when the drug permeation rate is rapid

  খ

  The release of the drug is controlled

  গ

  Suitable for drugs with large therapeutic indices

  ঘ

  The drug is contained in a powder form floating on liquid
• Which of the following is false in regarding reservoir devices?
  ক

  These devices are used when the drug permeation rate is rapid

  খ

  The release of the drug is controlled

  গ

  Suitable for low therapeutic indices

  ঘ

  The drug is contained in a powder form floating on liquid
• The absorption of the ophthalmic drug does not depend on which of the following?
  ক

  Physicochemical properties of the permeating molecule

  খ

  Drainage of tears

  গ

  Output of tears

  ঘ

  Size of the eyeball
• What are the characteristics of the mixed monolithic-reservoir devices?
  ক

  The drug has a large therapeutic index

  খ

  Drug permeation rate is high

  গ

  The drug-polymer matrix is layered by rate-controlling membrane

  ঘ

  Administration of emulsions
• What are the characteristics of the reservoir or membrane devices?
  ক

  The drug has a large therapeutic index

  খ

  Drug permeation rate is high

  গ

  Control drug release by partitioning the drug from the oil

  ঘ

  Administration of emulsions
• The rate at which monolithic devices transfer drugs to the patient body is proportional to _______________ of time.
  ক

  Square of time

  খ

  The square root of time

  গ

  Twice the time

  ঘ

  Half the time
• What are the characteristics of the monolithic devices?
  ক

  The drug has a large therapeutic index

  খ

  Aqueous solutions

  গ

  Control drug release by partitioning the drug from the oil

  ঘ

  Administration of emulsions
• Which of the following characteristics is suitable for transdermal drug?
  ক

  Large drug dose

  খ

  Large molecular size

  গ

  Drugs with narrow therapeutic indices

  ঘ

  Drugs which are metabolized in the skin
• Which of the following drugs cannot be given as transdermal administration?
  ক

  Drugs with very short half-lives

  খ

  Drugs with narrow therapeutic indices

  গ

  Easy removal and termination

  ঘ

  Drugs against peptic ulcer