Thalassaemia & haemoglobinopathies MCQ 6+

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• Thalassemia major
  ক

  Is a hereditary disease

  খ

  Can be diagnosed by hemoglobin electrophoresis

  গ

  Patients rarely survive beyond 5 year without treatment

  ঘ

  Is due to anomaly in chromosome 16

  ঙ

  Is incurable
• In case of thalassaemia following statements are true
  ক

  Total iron binding capacity - normal

  খ

  Ferritin level - normal

  গ

  Mean corpuscular volume - normal or decreased

  ঘ

  Cell morphology - dimorphic

  ঙ

  Serum transferrin receptor - normal
• Regarding Hemoglobinopathy
  ক

  Mutations in globin genes

  খ

  Defective haemoglobin production

  গ

  Hemolysis occur

  ঘ

  Normal haemoglobin

  ঙ

  Mutations in heme
• Haemoglobinopathies include
  ক

  Thalassemia

  খ

  Sickle cell anaemia

  গ

  Xerocytosis

  ঘ

  Hereditary Spherocytosis

  ঙ

  Eliptocyosis