Neonatal jaundice MCQ 32+

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• In neonatal hyperbilirubinemia risk of kernicterus increases with
  ক

  Hypoxia

  খ

  Acidosis

  গ

  Hypoalbuminemia

  ঘ

  Increased gestational age

  ঙ

  Warm weather
• Common causes of obstructive jaundice in a newborn include
  ক

  Hypoplasia of biliary tract

  খ

  Neonatal hepatitis

  গ

  Breast milk jaundice

  ঘ

  Physiological jaundice

  ঙ

  Galactosaemia
• Surgical causes of jaundice in children are
  ক

  Biliary atresia

  খ

  Choledochal cyst

  গ

  Infantile hypertrophic pyloric stenosis

  ঘ

  Frantz tumour

  ঙ

  Alpha-1 antitrypsin deficiency
• Cholestatic jaundice is associated with
  ক

  Direct hyperbilirubinemia

  খ

  Pruritus

  গ

  Indirect hyperbilirubinemia

  ঘ

  Hepatitis C infection

  ঙ

  Hepatitis A infection
• Cholestatic jaundice in children is associated with
  ক

  Pale stool

  খ

  Increased gamma glutamyl transpeptidase

  গ

  Choledochal cyst

  ঘ

  Indirect hyperbilirubinaemia

  ঙ

  Decreased alkaline phosphatase
• Physiological jaundice of infancy:
  ক

  Is more likely in premature infants

  খ

  Occurs in 1 in 3 normal infants

  গ

  Is first noticeable a week after birth

  ঘ

  Lasts 3-4 days

  ঙ

  Shows clay colored stools
• Physiological jaundice
  ক

  Is more common in premature baby

  খ

  Is due to short life span of RBC

  গ

  May cause anaemia in newborn

  ঘ

  Needs hospitalization

  ঙ

  Needs exchange transfusion
• Criteria of physiological jaundice
  ক

  Baby is healthy

  খ

  Indirect hyperbilirubinemia

  গ

  Subsides spontaneously

  ঘ

  Appears within 24 hours of birth

  ঙ

  Associated with hepatomegally
• Criteria of physiological jaundice are
  ক

  Indirect hyperbiIirubinaemia

  খ

  Appears on the 1st day of life

  গ

  Peak level at 3rd to 4th day of life

  ঘ

  Serum bilirubin is rising >5mg/kg/day

  ঙ

  Direct bilirubin fraction is > 2mg/dl
• Jaundice in a 3- day- old baby is due to
  ক

  Physiological jaundice

  খ

  Septicemia

  গ

  Rh incompatibilty

  ঘ

  Congenital hypothyroidiosm

  ঙ

  Biliary atresia
• Neonatal jaundice within 24 hours of birth is caused by
  ক

  ABO incompatibility

  খ

  Rh-incompatibility

  গ

  Congenital hypothyroidism

  ঘ

  Breast milk jaundice

  ঙ

  Prematurity
• Causes of conjugated hyperbilirubinaemia in neonate are
  ক

  Biliary atresia

  খ

  Neonatal sepsis

  গ

  Neonatal hepatitis

  ঘ

  ABO- incompatibility

  ঙ

  Breast milk jaundice
• Causes of unconjugated hyperbilirubinemia in newborn are:
  ক

  Hemolytic disease of newborn

  খ

  Prematurity

  গ

  Galactosemia

  ঘ

  Biliary atresia

  ঙ

  Congenital infection
• Neonatal jaundice is associated with:
  ক

  Galactosaemia

  খ

  Breast feeding

  গ

  Hypothyroidism

  ঘ

  Sickle-cell disease

  ঙ

  Achondroplasia
• Causes of unconjugated hyperbilirubianaemia are
  ক

  Breast milk jaundice

  খ

  Rh-incompatibility

  গ

  Neonatal hepatitis

  ঘ

  Rotor syndrome

  ঙ

  Biliary atresia
• The following conditions lead to conjugated hyperbilirubinaemia of infancy
  ক

  Intrauterine infection

  খ

  Septicemia

  গ

  Hemolytic disease of the newborn

  ঘ

  Breast milk jaundice

  ঙ

  Hereditary spherocytosis
• Causes of congenital nonhaemolytic hyperbilirubinaemia are
  ক

  Gilbert syndrome

  খ

  Dubin-Jhonson syndrome

  গ

  Crigler- Najjar syndrome

  ঘ

  Spherocytosis

  ঙ

  Glucose-6 phosphate dehydrogenase deficiency
• The causes of conjugated hyperbilirubinemia in neonate include:
  ক

  Choledochal cyst

  খ

  Cystic fibrosis

  গ

  Galactosaemia

  ঘ

  Gilbert’s syndrome

  ঙ

  Alpha thalassaemia
• Unconjugated hyperbilirubinemia occurs in
  ক

  Crigler-Najjar syndrome

  খ

  Gilbert’s syndrome

  গ

  Dubin- Johnson syndrome

  ঘ

  Rotor’s syndrome

  ঙ

  Acute viral hepatitis
• Conjugtated hyperbilirubinaemia occurs in
  ক

  Idiopathic neonatal hepatitis

  খ

  Biliary atresia

  গ

  ABO incompatibility

  ঘ

  Glucose-6-Phosphate deficiency

  ঙ

  Rh incompatibility
• The causes of conjugated hyperbilirubinaemia in neonate include
  ক

  Choledochal cyst

  খ

  Cystic fibrosis

  গ

  Galactosaemia

  ঘ

  Gilbert’s syndrome

  ঙ

  Alpha thalassaemia
• The cause of conjugated hyperbilirubinemia in newborn are
  ক

  Biliary atresia

  খ

  TORCH infection

  গ

  Crigler- Najjar syndrome

  ঘ

  Breast milk jaundice

  ঙ

  Polycythaemia
• The followings are causes of hyperbilirubinemia in neonates are
  ক

  Biliary atresia

  খ

  ABO blood group incompatibility

  গ

  Neonatal hepatitis

  ঘ

  Breast milk jaundice

  ঙ

  Choledochal cyst
• Direct hyperbilirubinemia in neonate is found in
  ক

  Sepsis

  খ

  Neonatal hepatitis

  গ

  Hypothyroidism

  ঘ

  Breast milk jaundice

  ঙ

  Crigler Najjar syndrome
• Causes of jaundice within 24 hours of birth are
  ক

  ABO incompatibility

  খ

  Rhesus incompatibility

  গ

  Sepsis

  ঘ

  Breast milk jaundice

  ঙ

  Physiological jaundice
• Causes of unconjugated hyperbilirubinemia at 3rd week in term babies are
  ক

  Breast milk jaundice

  খ

  G-6-PD deficiency

  গ

  Biliary atresia

  ঘ

  Congenital hyperthyroidism

  ঙ

  Congenital cholangiopathy
• Causes of unconjugated hyperbilirubinaemia
  ক

  Breast milk jaundice

  খ

  Glucose-6-phosphate dehydrogenase deficiency

  গ

  Rh-incompatibility

  ঘ

  Biliary atresia

  ঙ

  Choledochal cyst
• Following conditions cause neonatal cholestasis
  ক

  Galactosaemia

  খ

  Choledochal cyst

  গ

  Sepsis

  ঘ

  Glucose 6 phosphate dehydrogenase deficiency

  ঙ

  Criggler najjar syndrome
• The cause(s) of direct hyperbilirubinemia is/are
  ক

  Hypothyroidism

  খ

  Dubin-Johnson syndrome

  গ

  Biliary atresia

  ঘ

  Criggler -Najjar syndrome

  ঙ

  Physiological jaundice