Investigation MCQ 48+

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• Specimen obtained by liver biopsy can be used for
  ক

  Precise histological diagnosis

  খ

  Enzyme analysis

  গ

  Analysis of stored material

  ঘ

  Detection of viral marker

  ঙ

  Diagnosing space occupying lesion
• High serum-ascites albumin gradient (SAAG) is consistent with following conditions
  ক

  Cirrhosis

  খ

  Constrictive pericarditis

  গ

  Congestive cardiac failure

  ঘ

  Malabsorption syndrome

  ঙ

  Nephrotic syndrome
• Viatmin-K dependent factors are
  ক

  Factor IX

  খ

  Factor X

  গ

  Factor I

  ঘ

  Factor V

  ঙ

  Factor XI
• High serum-ascites albumin gradient occurs in
  ক

  Cirrhosis of liver

  খ

  Constrictive pericarditis

  গ

  Peritoneal carcinomatosis

  ঘ

  Peritoneal tuberculosis

  ঙ

  Nephrotic syndrome
• Obstructive jaundice usually
  ক

  Causes dark urine and pale stool

  খ

  Elevated serum level of alkaline phosphatase

  গ

  Raises the serum level of unconjugated bilirubin

  ঘ

  Reduces prothrombin time

  ঙ

  Increases urinary excretion of urobilinogen
• Haemolytic jaundice is associated with
  ক

  Increase in the concentration of bilirubin diglucoronide in the bile

  খ

  Increase in urobilinogen in urine

  গ

  Presence of bilirubin in urine

  ঘ

  Increase in the serum alkaline phosphatase

  ঙ

  Decrease in unconjugated bilirubin in the serum
• Laboratory features present in hemolytic jaundice are
  ক

  Raised serum bilirubin

  খ

  Increased urobilinogen in urine

  গ

  High serum alkaline phosphatase [Davidson's/P-852]

  ঘ

  Presence of bilirubin in urine

  ঙ

  Decreased stercobilinogen in stool
• Causes of low serum ascites albumin gradient
  ক

  Peritoneal carcinomatosis

  খ

  Peritoneal tuberculosis

  গ

  Nephrotic syndrome

  ঘ

  Constrictive pericarditis

  ঙ

  Budd-Chiari syndrome
• A patient with obstructive jaundice will have
  ক

  Bilirubin in the urine.

  খ

  Raised serum alkaline phosphatase level.

  গ

  Urobilinogen in the urine.

  ঘ

  High level of unconjugated bilirubin.

  ঙ

  Raised serum level of stercobilinogen.
• Tests for synthetic function of liver are estimation of
  ক

  Serum total protein concentration

  খ

  Serum albumin concentration

  গ

  Prothrombin time

  ঘ

  Serum bilirubin concentration

  ঙ

  Galactose tolerance test
• Synthetic function of liver is assessed by measurement of
  ক

  Serum albumin

  খ

  Prothombin time

  গ

  Serum alkaline phosphatase

  ঘ

  Serum gamma glutamyl transferase

  ঙ

  SGPT
• Tests for assessing synthetic functions of liver are
  ক

  Serum albumin

  খ

  Prothromhin time

  গ

  Serum bilirubin

  ঘ

  Alanine transaminases

  ঙ

  Alkaline phosphatases
• Liver function could be assessed by
  ক

  Serum alanine transaminase level

  খ

  Gamma-glutamyl transpeptidase level

  গ

  Bleeding time

  ঘ

  Serum acid phosphatase level

  ঙ

  Serum globulin level
• Hepatocellular damage is indicated by raised
  ক

  SGPT

  খ

  SCOT

  গ

  Gamma glutamyl transpeptidase

  ঘ

  Alkaline phosphatase

  ঙ

  Creatinine kinase
• High serum-ascites albumin gradient is found in
  ক

  Budd-Chiari syndrome

  খ

  Cirrhosis

  গ

  Nephrotic syndrome

  ঘ

  Myxedema

  ঙ

  Tuberculous peritonitis
• Alkaline phosphatase is raised in
  ক

  Osteomalacia

  খ

  Paget’s disease

  গ

  Osteoporosis

  ঘ

  Haemolytic anaemia

  ঙ

  Post menopausal syndrome
• Cause/s of virilism in female is/are
  ক

  Arrhenoblastoma

  খ

  Congenital adrenal hyperplasia

  গ

  Hilar cell tumor of the ovary

  ঘ

  Addison’s disease

  ঙ

  Panhypopituitarism
• Causes of hirsutism include
  ক

  Polycystic ovary syndrome

  খ

  Adrenal adenoma

  গ

  Congenital adrenal hyperplasia

  ঘ

  Medullary carcinoma of thyroid

  ঙ

  Polycystic kidney disease
• Causes of macroglossia are
  ক

  Down’s syndrome

  খ

  Primary amyloidosis

  গ

  Cretinism

  ঘ

  Pellagra

  ঙ

  Klinefelter’s syndrome
• In subclinical hyperthyroidism
  ক

  TSH receptor antibodies may be positive or negative

  খ

  TSH

  গ

  FT4 and FT3 are all increased

  ঘ

  TSH

  ঙ

  FT4 and FT3 are all decreased

  চ

  TSH is suppressed but FT4 and FT3 fall within the reference range

  ছ

  TSH is suppressed but FT4 and FT3 always raised
• Following are the interpretation of thyroid function test
  ক

  Low T4 and high TSH suggests hypothyroidism

  খ

  Normal T4 with high TSH suggest subclinical hypothyroidism

  গ

  High FT4 with very low TSH suggest over replacement

  ঘ

  Very low TSH and normal T3 suggest hyperthyroidism

  ঙ

  Low T4 and high T3 is diagnostic of hypothyroidism
• In subclinical hypothyroidism
  ক

  Antibody to thyroid peroxidase has prognostic value

  খ

  Treatment is needed in pregnancy

  গ

  Risk of developing atrial fibrillation increases

  ঘ

  TSH is normal

  ঙ

  FT4 is very low
• Causes of microcytic hypochromic anaemia are
  ক

  Iron deficiency anaemia

  খ

  α- thalassemia

  গ

  β- thalassemia

  ঘ

  Anaemia of chronic disease

  ঙ

  G-6 PD deficiency
• MCV and MCHC are normal, but total count of RBC is reduced may be due to
  ক

  Acute hemorrhage

  খ

  Renal failure

  গ

  Chronic inflammation

  ঘ

  Iron deficiency

  ঙ

  Lack of intrinsic factor
• Microcytic hypochromic anaemia is the features of
  ক

  Iron deficiency anaemia

  খ

  Congenital haemolytic anaemia

  গ

  Anaemia due to chronic hemorrhage

  ঘ

  Megaloblastic anaemia

  ঙ

  Aplastic anaemia
• Microcytic hypochromic anemia is found in the following conditions
  ক

  Iron deficiency anemia

  খ

  Sideroblastic anemia

  গ

  Thalassemia

  ঘ

  Aplastic anemia

  ঙ

  Chronic myeloid leukemia
• Features of anemia of chronic disease are
  ক

  Low reticulocyte count

  খ

  Raised hepcidin level

  গ

  Normal or low ferritin

  ঘ

  High total iron binding capacity

  ঙ

  High soluble transferrin receptor
• Effects of anemia on the circulatory systems are
  ক

  Increased quantities of blood returned to the heart

  খ

  Increased workload on the heart

  গ

  Increased heart rate

  ঘ

  Raised blood viscosity

  ঙ

  Increased resistance in the peripheral blood vessels
• Microcytic hypochromic anaemia is found in
  ক

  Sideroblastic anaeamia

  খ

  Thalassemia major

  গ

  Acute blood loss

  ঘ

  Chronic renal failure

  ঙ

  Lymphoma
• Causes of anemia in chronic renal failure are
  ক

  Increased blood loss

  খ

  Erythropoietin deficiency

  গ

  Bone marrow depression

  ঘ

  Anorexia

  ঙ

  Faulty globin synthesis