Insulin MCQ 27+

Test your knowledge with important Insulin MCQ and their applications. These MCQs are beneficial for competitive exams too. Explore 57 + more Insulin MCQs at Bissoy

• What is the name of the hypothesis which describes the reciprocal relationship between cAMP and cGMP in the action of insulin?
  ক

  Wobbler hypothesis

  খ

  JAK-KINASE hypothesis

  গ

  Yin Yang hypothesis

  ঘ

  Reciprocal hypothesis
• What happens to the insulin receptors when the concentration of insulin increases in the blood?
  ক

  Decreases

  খ

  Increases

  গ

  Inactivates

  ঘ

  Activates
• Human insulin gene receptor is found on which chromosome?
  ক

  Chromosome 19

  খ

  Chromosome 18

  গ

  Chromosome 21

  ঘ

  Chromosome 15
• Which among the following cells have a higher concentration of the protease enzymes involved in insulin degradation?
  ক

  Muscles

  খ

  Bones and embryo

  গ

  Brain and RBC

  ঘ

  Liver and kidney
• Which are the two enzymes that take part in insulin catabolism?
  ক

  Peptidase and Glutathione-insulin transhydrogenase

  খ

  Lipases and Glutathione-insulin transhydrogenase

  গ

  Proteases and Glutathione-insulin transhydrogenase

  ঘ

  Isomerases and Glutathione-insulin transhydrogenase
• Which enzyme is otherwise known as insulinase?
  ক

  Proteases

  খ

  Glutathione-insulin transhydrogenase

  গ

  Trypsin like proteases

  ঘ

  Peptidases
• Which among the following is the correct order of formation of insulin?
  ক

  Pre proinsulin > Pro Insulin

  খ

  Pre proinsulin > Insulin

  গ

  Pro insulin > Pre proinsulin > insulin

  ঘ

  Pre proinsulin > Pro insulin > Insulin
• Which type of porcine insulin is used in the treatment of diabetes mellitus?
  ক

  De alaninated

  খ

  De glycinated

  গ

  De valinated

  ঘ

  Threonine present
• The difference between human insulin and porcine insulin is located in which amino acid?
  ক

  Number 30 amino acid of A chain

  খ

  Number 30 amino acid of B chain

  গ

  Number 20 amino acid of A chain

  ঘ

  Number 20 amino acid of B chain
• Pro-insulin when compared to other forms of insulin is the most active form.
  ক

  True

  খ

  False
• Insulin is an important anabolic hormone.
  ক

  True

  খ

  False
• What happens to insulin hormone when its disulfide bond is broken with some reducing agents?
  ক

  Activated

  খ

  Inactivated

  গ

  Released

  ঘ

  Stored
• Which among the following cells are unresponsive to insulin hormone?
  ক

  RB cells

  খ

  Muscle cells

  গ

  Liver cells

  ঘ

  Adipose tissues
• Side-effects of insulin therapy are
  ক

  Hypoglycemia

  খ

  Weight gain

  গ

  Hypertension

  ঘ

  Hyperkalemia

  ঙ

  Chronic renal failure
• An individual with insulin resistance
  ক

  Usually shows elevated fasting blood glucose level

  খ

  Usually shows elevated fasting insulin level

  গ

  Will eventually become diabetic

  ঘ

  Is usually obese

  ঙ

  Is treated by insulin injection
• Factors simulating insulin secretions are
  ক

  Glucose

  খ

  Gastrin

  গ

  Acetylcholine

  ঘ

  Insulin

  ঙ

  Somatostatin
• Insulin increases glucose uptake in following tissues
  ক

  Skeletal muscles

  খ

  Adipose tissue

  গ

  Renal tubules

  ঘ

  Intestinal mucosa

  ঙ

  Red blood cell
• Important actions of Insulin are
  ক

  Increased transport of glucose into cell

  খ

  Stimulation of protein synthesis

  গ

  Stimulation of glycolytic enzymes

  ঘ

  Inhibition of amino acid transport into cells

  ঙ

  Stimulation of gluconeogenic enzymes
• Actions of insulin include
  ক

  Increased transport of amino acid

  খ

  Stimulation of protein synthesis

  গ

  Activation of glycogen synthesis

  ঘ

  Decrease K+ transport in to the cells

  ঙ

  Stimulation of glyconeogenic enzymes
• The mechanism of action of insulin on adipose tissue are increased
  ক

  Activity of lipoprotein lipase

  খ

  Uptake of potassium

  গ

  Deposition of triglyceride

  ঘ

  Activity of hormone sensitive lipase

  ঙ

  Lipolysis
• Insulin decreases
  ক

  Ketogenesis

  খ

  Glycogenolysis

  গ

  Gluconeogenesis

  ঘ

  Lipogenesis

  ঙ

  Glycolysis
• Insulin causes
  ক

  Reduced gluconeogenesis

  খ

  Synthesis of protein from amino acids

  গ

  Entry of potassium into cells

  ঘ

  Increase glycogenolysis

  ঙ

  Lipolysis
• Secretion of insulin is increase by
  ক

  Glucose

  খ

  Vagal stimulation

  গ

  Somatostatin

  ঘ

  Thiazide diuretics

  ঙ

  Stress
• Following are the stimuli for insulin release
  ক

  Fatty acids and Ketone bodies

  খ

  Vagal nerve stimulation

  গ

  Drugs like sulphonylureas

  ঘ

  Adrenergic agents

  ঙ

  Serotonin
• Insulin increases activity of
  ক

  Glucokinase

  খ

  Glycogen synthase

  গ

  Lipoprotein lipase

  ঘ

  Hormone sensitive lipase

  ঙ

  Glucose-6-phosphatase
• Glucose transport is insulin sensitive in the
  ক

  Adipocytes

  খ

  Skeletal muscle

  গ

  Brain

  ঘ

  Erythrocytes

  ঙ

  Cornea