Inflammatory mediators MCQ 22+

Test your knowledge with important Inflammatory mediators MCQ and their applications. These MCQs are beneficial for competitive exams too. Explore 52+ more Inflammatory mediators MCQs on Bissoy. Bissoy App

• Vasodilation in inflammation in mediated by
  ক

  Histamine

  খ

  Complement C5a

  গ

  Prostaglandin E1

  ঘ

  Leukotiene B4

  ঙ

  Interleukin-1
• Arachidonic acid metabolites causing vasoconstriction are
  ক

  Thromboxane A2

  খ

  Leucotriene D4

  গ

  Prostacyclin

  ঘ

  Leucotriene B4

  ঙ

  Prostaglandin D2
• Preformed chemical mediators of inflammation are
  ক

  Histamine

  খ

  Lysosomal enzyme

  গ

  Prostaglandin

  ঘ

  Platelet activating factor

  ঙ

  Leukotriene
• Preformed mediators of immediate hypersensitivity are
  ক

  Vasoactive amines

  খ

  Proteoglycans

  গ

  Leukotrienes

  ঘ

  Prostaglandin D

  ঙ

  Platelet activating factor
• The following chemical mediators are responsible for vasodilatation in acute inflammation
  ক

  Bradykinin

  খ

  Histamin

  গ

  Nitric oxide

  ঘ

  Prostaglandins

  ঙ

  Leukotriene
• Vascular permeability of capillary is increased by
  ক

  Il-1

  খ

  Bradykinin

  গ

  Serotonin

  ঘ

  IL-6

  ঙ

  Thromboxane A2
• During inflammation, formation of endothelial gaps in venules is mediated by
  ক

  Leukotrienes

  খ

  Histamine

  গ

  Bradykinin

  ঘ

  Vascular endothelium derived growth factor

  ঙ

  Toxins
• Example of chronic disorders caused by leukocyte induced injury are
  ক

  Arthritis

  খ

  Asthma

  গ

  Atherosclerosis

  ঘ

  Glomerulonephritis

  ঙ

  Septic shock
• In acute inflammation, the chemical mediators have the following role
  ক

  Histamin causes vasodilatation

  খ

  C3a is a chemotactic agent

  গ

  TNF causes direct tissue damage

  ঘ

  Pain is produced by PAF

  ঙ

  Leukotriene have no effect on blood vessels
• Histamine in the body
  ক

  Is synthesized by decarboxylation of histidine

  খ

  Is primarily stored in Mast cells

  গ

  Comes mainly from intestinal bacteria

  ঘ

  Is produced in large amounts by growing cells

  ঙ

  e ) Is excreted primarily unchanged
• Products of mast cell degranulation are
  ক

  Leukotrienes

  খ

  Thromboxane A2

  গ

  Histamine

  ঘ

  Serotonin

  ঙ

  Eosinophilic chemotactic factor
• Nitric oxide causes
  ক

  Vascular smooth muscle relaxation

  খ

  Inhibition of bacterial replication

  গ

  Inhibition of tumour growth

  ঘ

  Increased leukocyte adhesion

  ঙ

  Increased platelet adhesion
• Nitric oxide
  ক

  Is important for brain function

  খ

  Is an autacoids

  গ

  Is concerned with receptive relaxation of the gut

  ঘ

  Originates from arginine

  ঙ

  Reduces renal blood flow
• Leukotrienes play a role in
  ক

  Chemotaxis

  খ

  Vasoconstriction

  গ

  Increased vascular permeability

  ঘ

  Platelet aggregation

  ঙ

  Bronchodilation
• Synthesis of nitric oxide requires
  ক

  NADPH

  খ

  Molecular oxygen

  গ

  Nitric oxide synthase

  ঘ

  Arginine

  ঙ

  ATP
• Mediators that cause vasodilation
  ক

  Prostaglandins

  খ

  Bradykinin

  গ

  Nitric oxide

  ঘ

  Histamine

  ঙ

  C5a and C3a
• Capillary permeability is increased by
  ক

  Histamine

  খ

  Viral infection

  গ

  Burn

  ঘ

  Vitamin C excess

  ঙ

  Prolonged ischemia
• The following mediators increase capillary permeability in acute inflammation
  ক

  Histamine

  খ

  Bradykinin

  গ

  Prostacyclin

  ঘ

  Platelet Derived Growth Factor (PDG

  ঙ

  Angiotensin
• In inflammation
  ক

  Macrophage cause tissue injury

  খ

  C5a is chemotactic for macrophage

  গ

  Bradykinin causes pain

  ঘ

  Mast cells release major basic protein which recruits eosinophils

  ঙ

  NO causes vasoconstriction
• Chemical mediators which causes vasodilatation are
  ক

  Histamine

  খ

  Bradykinin

  গ

  Prostaglandins

  ঘ

  Platelet activating factors

  ঙ

  Leukotrienes
• Histamine is released from
  ক

  Basophils

  খ

  Mast cells

  গ

  Platelets

  ঘ

  Endothelial cells

  ঙ

  Macrophages