Histopathology MCQ 36+

Test your knowledge with important Histopathology MCQ and their applications. These MCQs are beneficial for competitive exams too. Explore 66+ more Histopathology MCQs on Bissoy. Bissoy App

• The study of pathology includes
  ক

  Knowledge about etiology

  খ

  Understanding pathogenesis of disease

  গ

  Recognizing changes in the tissue

  ঘ

  Skill of preparation of histopathology slides

  ঙ

  Only diagnosis of histopathology and cytology slides
• Routine stains used in histopathology and cytopathology is/are
  ক

  Haematoxylin and Eosin

  খ

  Pap’s stain

  গ

  Fite stain

  ঘ

  PAS stain

  ঙ

  Crystal violet
• Brown induration is seen in
  ক

  Heart failure

  খ

  COPD

  গ

  Pulmonary oedema

  ঘ

  Septic shock

  ঙ

  Pulmonary embolism
• Immunohistochemistry is employed to
  ক

  Distinguish neoplastic from non-neoplastic lesion

  খ

  Distinguish benign from malignant lesion

  গ

  Localise the cell of origin of tumour

  ঘ

  Distinguish primary from metastatic cancer

  ঙ

  Detect autoantibodies in the serum
• Heavy metals toxic to human health are
  ক

  Lead

  খ

  Mercury

  গ

  Cadmium

  ঘ

  Copper

  ঙ

  Selenium
• Frozen section is indicated in
  ক

  Intraoperative categorization of tumour as benign or malignant

  খ

  Intraoperative diagnosis of Hirschprung disease

  গ

  To see the resection margins of a malignant tumour whether free or involved

  ঘ

  Categorization of malignant tumours

  ঙ

  Scoring of hepatic inflammation
• Frozen section is done
  ক

  To see surgical margins of a malignant tumour

  খ

  To see ganglion cells in suspected Hirschsprung disease

  গ

  Peroperatively

  ঘ

  For immunohistochemistry

  ঙ

  To categorize malignant tumour
• Frozen section is useful because it
  ক

  Can predict malignancy during operation

  খ

  Is cheap

  গ

  Preserves tissue substances like fat

  ঘ

  Is more accurate than routine section

  ঙ

  Can replace routine section
• Frozen section biopsy is used in
  ক

  Categorization of tumor as benign or malignant

  খ

  Identification of ganglion cell in Hirschsprung disease

  গ

  To see resection margins of a malignant tumour

  ঘ

  Identification of organism in tissue

  ঙ

  Definitive diagnosis of a tumour
• The following are the examples of samples for cytology examination
  ক

  Sputum

  খ

  Scraping from oral ulcer

  গ

  Urine

  ঘ

  Endoscopic biopsy

  ঙ

  Core needle biopsy
• Exfoliative cytology may play role in the diagnosis of the following malignant disorders
  ক

  Bronchogenic carcinoma

  খ

  Malignant urothelial tumors

  গ

  Cervical cancer

  ঘ

  Gastric cancer

  ঙ

  Sino nasal cancer
• Exfoliative cytology has a diagnostic role in detection of
  ক

  Bronchogenic carcinoma

  খ

  Transitional cell carcinoma

  গ

  Carcinoma cervix

  ঘ

  Esophageal carcimoma

  ঙ

  Renal cell carcinoma
• Fine Needle Aspiration Cytology
  ক

  Is less expensive as a test

  খ

  Is suitable for detection of metastasis in lymph nodes

  গ

  Is a better method of tumor diagnosis than histopathology

  ঘ

  Is not suitable for deep seated tumors.

  ঙ

  Can be performed by nurses
• Fine needle aspiration cytology FNAC is not suitable for the diagnosis of
  ক

  Follicular non-hodgkin lymphoma

  খ

  Nodular sclerosis hodgkin lymphoma

  গ

  Fibromatosis

  ঘ

  Axillary lymph node metastasis

  ঙ

  Lymph node tuberculosis
• A 25 year female has got a FNAC report of her left sided breast lump stated as suspicious cytology. Following steps should he advised?
  ক

  Biopsy

  খ

  Repeat FNAC

  গ

  Frozen section

  ঘ

  Mammography

  ঙ

  Mastectomy
• Image guidance is for FNAC of following organs
  ক

  Space occupying lesion of liver

  খ

  Para- aortic lymph node

  গ

  Breast lump

  ঘ

  Chest wall swelling

  ঙ

  Cervical lymph node
• FNAC is done for the diagnosis of
  ক

  Tubercular lymphadenitis

  খ

  Papillary carcinoma of thyroid

  গ

  Hemangioma of liver

  ঘ

  Cystadenocarcinoma of ovary

  ঙ

  Stromal invasion of a tumor
• A biopsy is suitable for proper histological assessment if
  ক

  Normal margins are included

  খ

  Accompanied by clinical information

  গ

  It is autolysed

  ঘ

  Frozen for preservation

  ঙ

  Preserved in 10% alcohol
• 10% Formalin solution
  ক

  Is an irritant agent for eyes

  খ

  Is a colourless fluid

  গ

  Prevents autolysis of biopsy samples

  ঘ

  Is used as a fixative for cytology samples

  ঙ

  Should be used for sending frozen section samples
• The solutions used as fixatives for pathological specimensare
  ক

  10% formation

  খ

  95% ethanol

  গ

  40% formaldehyde gas

  ঘ

  Normal saline

  ঙ

  Liquid paraffin
• The following fluids are used as fixative for biopsy samples
  ক

  Bouin’s fluid

  খ

  10% formalin

  গ

  Normal saline

  ঘ

  Liquid paraffin

  ঙ

  Savlon
• Preservatives are used after biopsy to
  ক

  Process the tissue for microtome sectioning

  খ

  Prevent autolysis

  গ

  Stabilize tissue architecture

  ঘ

  Prevent bacterial growth

  ঙ

  Proceed for bacterial culture
• The following chemicals can be used as fixatives for biopsy samples
  ক

  Zenker’s solution

  খ

  Bouin’s solution

  গ

  10% buffered formalin

  ঘ

  Normal saline

  ঙ

  Paraffin wax
• Following chemicals/ Substances are used as fixative for biopsy/cytology samples:
  ক

  95% alcohol

  খ

  10% formalin

  গ

  Xylene

  ঘ

  Liquid paraffin

  ঙ

  Normal saline
• Chemicals used as tissue fixatives are
  ক

  Alcohol

  খ

  Formalin

  গ

  Normal saline

  ঘ

  Liquid paraffin

  ঙ

  Glycerine
• The followings are used as fixative for surgical specimen
  ক

  10% buffered formalin

  খ

  Glutaraldehyde

  গ

  Bouin's solution

  ঘ

  40% formalin

  ঙ

  Normal saline
• Fixatives used in cytology are
  ক

  95% ethanol

  খ

  Commercial spray fixative

  গ

  Glutaraldchyde

  ঘ

  10% buffered formalin

  ঙ

  Normal saline
• Autolysis of biopsy samples is prevented by
  ক

  10% formalin

  খ

  Freezing

  গ

  Glutaraldehyde

  ঘ

  10% fomaldehyde

  ঙ

  10% dextrose
• Fixatives used in routine histopathological examination are
  ক

  10% formalin

  খ

  Bouin's solution

  গ

  40% formalin

  ঘ

  Hartman's solution

  ঙ

  Normal saline
• Functional purpose of fixatives in biopsy samples includes
  ক

  Preventing autolysis

  খ

  Facilitating tissue processing

  গ

  Preventing growth of saprophytes

  ঘ

  Keeping tissue viable

  ঙ

  Dissolving calcium from bone