Hepatology MCQ 90+

Test your knowledge with important Hepatology MCQ and their applications. These MCQs are beneficial for competitive exams too. Explore 120 + more Hepatology MCQs at Bissoy

Drug induced hepatitis occurs in

ক
Methyldopa

খ
Captopril

গ
Zidovudine

ঘ
Sodium valproate

ঙ
Tetracycline
Choledocal cyst presents with the following complaints

ক
Lump in the right upper quadrant of the abdomen

খ
May develop cancer

গ
Upper abdominal pain

ঘ
Progressive jaundice

ঙ
Hepatosplenomegaly
Autoantibody/ies present in autoimmune hepatitis is/are

ক
ANA

খ
Anti -LKM

গ
Antibodies to soluble liver antigen

ঘ
p-ANCA

ঙ
c-ANCA
Contraindication of percutaneous liver biopsy include

ক
Non- cooperative patients

খ
Prothrombin time> 4 sec

গ
Platelet count > lOOx 109/L

ঘ
Past history of melaena

ঙ
Patients with positive HBsAg
Wilsons disease

ক
Is caused due to mutation of ATP7B gene on chromosome 13

খ
May present with features of parkinsonism

গ
May be cured by liver transplantation

ঘ
Is characterized by increased synthesis of ceruloplasmin

ঙ
Is characterized by red colored urine
Autoimmune liver diseases are

ক
Primary sclerosing cholangitis

খ
Autoimmune hepatitis

গ
Primary biliary cirrhosis

ঘ
Progressive systemic sclerosis

ঙ
Secondary sclerosing cholangitis
Hepatorenal syndrome

ক
Occurs in advanced cirrhosis

খ
May be precipitated by vigorous diuresis

গ
Is best treated with liver transplantation

ঘ
Urine output is low with high urinary sodium concentration

ঙ
Carries an excellent prognosis
In hepatorenal syndrome

ক
Urine output is low

খ
May be precipitated by NSAID

গ
Liver transplantation is the best option of treatment

ঘ
Urinary sodium is high

ঙ
Renal histology is abnormal
Features of hepatorenal syndrome

ক
Low serum osmolarity

খ
Raised serum creatinine

গ
Increased serum uric acid

ঘ
High urinary sodium

ঙ
Low blood urea nitrogen
Regarding hepatorenal syndrome

ক
Renal failure is functional

খ
Kidneys are smaller on imaging

গ
It occurs in advanced cirrhosis with ascites

ঘ
It may be associated with spontaneous bacterial peritonitis

ঙ
It is characterised by significant proteinuria
Steatosis

ক
May lead to cirrhosis

খ
May lead to hepatocellular carcinoma

গ
May occur in heart

ঘ
Is caused by alcohol abuse only

ঙ
Is only seen in liver
Mechanisms of fatty change of the liver are

ক
Increased free fatty acid delivery to liver

খ
Reversible liver cell injury

গ
Increased formation of triglyceride

ঘ
Decreased formation of apoprotein

ঙ
Liver cell apoptosis
Acute fatty liver of pregnancy

ক
There are biochemical evidences of liver failure

খ
Prognosis is excellent

গ
Occurs in early pregnancy

ঘ
There is macrovascular steatosis in the liver

ঙ
Physical findings may be minimal
Drugs causing fatty liver are

ক
Alcohol abuse

খ
Tetracycline

গ
Valproic acid

ঘ
Chlorpromazine

ঙ
Nitrofurantion
Fatty change in liver can lead to

ক
Acute hepatitis

খ
Cirrhosis of liver

গ
Chronic hepatitis

ঘ
Hepatic adenoma

ঙ
Acute liver failure
Fatty change of the liver occurs in

ক
Starvation

খ
Protein energy malnutrition (PE

গ
Obesity

ঘ
Haemochromatosis

ঙ
Wilsonâs disease
Fatty changes in liver occur

ক
Starvation

খ
Protein energy malnutrition

গ
Diabetes mellitus

ঘ
Vitamin E deficiency

ঙ
Beriberi
Complications of portal hypertension include

ক
Variceal bleeding

খ
Hepatic encephalopathy

গ
Congestive gastropathy

ঘ
Spider angioma

ঙ
Testicular atrophy
Feature/s of portal hypertension is/are

ক
Ascites

খ
Splenomegaly

গ
Variceal bleeding

ঘ
Testicuiar atrophy

ঙ
Gynaecomastia
In liver failure there is likely to be

ক
Salt & water deprivation

খ
Dependent oedema

গ
Impaired absorption of fat

ঘ
Intoxication after eating a high protein meal

ঙ
Raised blood urea
Biochemical features of fulminating hepatic failure are

ক
Low blood urea nitrogen

খ
Prolongation of prothrombin time

গ
Low serum albumin

ঘ
Metabolic alkalosis

ঙ
Low blood ammonia level
A cirrhosis case is likely to due to alpha 1 antitrypsin deficiency if

ক
The patient is pizz genotype

খ
If the patient shows typical clinical features at onset

গ
His/her liver biopsy shows alpha 1 antitrypsin globules

ঘ
His/her plasma alpha 1 antitrypsin is low

ঙ
He/she has early onset has severe disease
Fulminant hepatitis is caused by

ক
Hepatitis A

খ
Hepatitis B

গ
Wilson disease

ঘ
Phenytoin

ঙ
Galactosaemia
The following biochemical disturbances occur in fulminating hepatic failure

ক
Metabolic acidosis

খ
Hyperkalaemiaia

গ
Hypoglycaemia

ঘ
Fall in Po2

ঙ
Hypernatraemia
Fulminant hepatic failure is characterized by

ক
Hepatic encephalopathy

খ
INR>3

গ
Coagulopathy

ঘ
Absence of hemorrhage

ঙ
Its occurrence usually 6 months after the onset of acute liver disease
In cirrhosis of liver encephalopathy may be precipitated by

ক
Hypokalemia

খ
High protein diet

গ
Paracentesis

ঘ
Injection of vitamin K

ঙ
High carbohydrate diet
Cirrhosis of liver is caused by the followings

ক
Hepatitis C virus

খ
Hepatitis B virus

গ
Hepatitis A virus

ঘ
Cytomegalovirus

ঙ
Epstein Barr virus
In hepatic failure the following biochemical abnormalities may be found

ক
Increased plasma globulin

খ
Increased the blood ammonia concentration

গ
Impaired glucose tolerance

ঘ
Increased plasma albumin concentration

ঙ
Increased the blood urea
Causes of chronic liver disease are

ক
Hepatitis D virus infection

খ
Hepatitis C virus infection

গ
Alpha 1 antitrypsin deficiency

ঘ
Hepatitis E virus infection

ঙ
Hepatitis A virus infection
Following drugs are contraindicated in decompensated cirrhosis of liver

ক
Oral hypoglycemic agents

খ
Pegylated interferon

গ
Antihypertensives

ঘ
Propranolol

ঙ
Tenofovir