Endocrine physiology MCQ 133+

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• The followings are hormones of adipose tissue
  ক

  Leptin

  খ

  Resistin

  গ

  Adoponectin

  ঘ

  Ghrelin

  ঙ

  Dopamin
• During sleep, there is a fall of plasma level of
  ক

  Cortisol

  খ

  Insulin

  গ

  Adrenaline

  ঘ

  ADH

  ঙ

  Growth hormone
• Causes of secondary hyperaldosteronism is/are
  ক

  Nephrotic syndrome

  খ

  Cirrhosis of liver

  গ

  Congestive cardiac failure

  ঘ

  Conn’s syndrome

  ঙ

  Diabetes insipidus
• The hormones promoting lipolysis is/are
  ক

  Epinephrine

  খ

  Growth hormone

  গ

  Glucagon

  ঘ

  Insulin

  ঙ

  Testosterone
• Hormones which act on breast are
  ক

  Oestrogen

  খ

  Progesterone

  গ

  Growth hormone

  ঘ

  Prolactin

  ঙ

  Cortisol
• Human chorionic gonadotropic hormone
  ক

  Acts on ovaries to maintain corpus luteum

  খ

  Is analogous to luteinizing hormone

  গ

  Can be detected in urine as early sign of pregnancy

  ঘ

  Protein in nature

  ঙ

  Is released from anterior pituitary
• Human chorionic gonadotrophin
  ক

  Is a good measure of placental function

  খ

  Is secreted in maternal urine

  গ

  Is secreted by the cytotrophoblast

  ঘ

  Causes degeneration of corpus luteum

  ঙ

  Reaches maximum levels in the last trimaster
• Source of progesterone in the female body are
  ক

  Corpus luteum of the ovary

  খ

  Adrenal cortex

  গ

  Placenta

  ঘ

  Breast

  ঙ

  Pituitary
• Estrogen causes
  ক

  Development of stromal tissues of breast.

  খ

  Increased osteoblastic activity.

  গ

  Change of the vaginal epithelium from cubodial to stratified type.

  ঘ

  Enhancement of Na+ Cl- and water reabsorption from the kidney.

  ঙ

  Secretory changes of the uterine endometrium.
• The sources of estrogen during the second and third trimesters of pregnancy is the
  ক

  Fetal adrenal gland

  খ

  Fetal liver

  গ

  Placenta

  ঘ

  Maternal ovaries

  ঙ

  Fetal ovaries
• Testosterone
  ক

  Is responsible for development of male external genitalia

  খ

  Is a steroid hormone

  গ

  Is responsible for union of epiphysis and shaft of long bone

  ঘ

  Cause thick sebaceous secretion

  ঙ

  Influences fetal brain
• Hypoglycemia causes increase secretion of
  ক

  Glucagon

  খ

  Thyroxine

  গ

  Growth hormone

  ঘ

  Epinephrine

  ঙ

  Testosterone
• Blood glucose is increased by
  ক

  Adrenaline

  খ

  Glucagon

  গ

  Growth hormone

  ঘ

  Aldosterone

  ঙ

  Testosterone
• Blood glucose level is increased by
  ক

  Glucagon

  খ

  Catecholamine

  গ

  Cortisol

  ঘ

  Aldosterone

  ঙ

  Parathyroid hormone
• In glucose homeostasis GLP-1
  ক

  Delays gastric emptying

  খ

  Increases satiety

  গ

  Stimulates glucagon release

  ঘ

  Inhibits insulin release

  ঙ

  Increases leptin secretion
• An individual with insulin resistance
  ক

  Usually shows elevated fasting blood glucose level

  খ

  Usually shows elevated fasting insulin level

  গ

  Will eventually become diabetic

  ঘ

  Is usually obese

  ঙ

  Is treated by insulin injection
• Factors simulating insulin secretions are
  ক

  Glucose

  খ

  Gastrin

  গ

  Acetylcholine

  ঘ

  Insulin

  ঙ

  Somatostatin
• Insulin increases glucose uptake in following tissues
  ক

  Skeletal muscles

  খ

  Adipose tissue

  গ

  Renal tubules

  ঘ

  Intestinal mucosa

  ঙ

  Red blood cell
• Important actions of Insulin are
  ক

  Increased transport of glucose into cell

  খ

  Stimulation of protein synthesis

  গ

  Stimulation of glycolytic enzymes

  ঘ

  Inhibition of amino acid transport into cells

  ঙ

  Stimulation of gluconeogenic enzymes
• Actions of insulin include
  ক

  Increased transport of amino acid

  খ

  Stimulation of protein synthesis

  গ

  Activation of glycogen synthesis

  ঘ

  Decrease K+ transport in to the cells

  ঙ

  Stimulation of glyconeogenic enzymes
• The mechanism of action of insulin on adipose tissue are increased
  ক

  Activity of lipoprotein lipase

  খ

  Uptake of potassium

  গ

  Deposition of triglyceride

  ঘ

  Activity of hormone sensitive lipase

  ঙ

  Lipolysis
• Insulin decreases
  ক

  Ketogenesis

  খ

  Glycogenolysis

  গ

  Gluconeogenesis

  ঘ

  Lipogenesis

  ঙ

  Glycolysis
• Insulin causes
  ক

  Reduced gluconeogenesis

  খ

  Synthesis of protein from amino acids

  গ

  Entry of potassium into cells

  ঘ

  Increase glycogenolysis

  ঙ

  Lipolysis
• Secretion of insulin is increase by
  ক

  Glucose

  খ

  Vagal stimulation

  গ

  Somatostatin

  ঘ

  Thiazide diuretics

  ঙ

  Stress
• Following are the stimuli for insulin release
  ক

  Fatty acids and Ketone bodies

  খ

  Vagal nerve stimulation

  গ

  Drugs like sulphonylureas

  ঘ

  Adrenergic agents

  ঙ

  Serotonin
• Insulin increases activity of
  ক

  Glucokinase

  খ

  Glycogen synthase

  গ

  Lipoprotein lipase

  ঘ

  Hormone sensitive lipase

  ঙ

  Glucose-6-phosphatase
• Glucose transport is insulin sensitive in the
  ক

  Adipocytes

  খ

  Skeletal muscle

  গ

  Brain

  ঘ

  Erythrocytes

  ঙ

  Cornea
• Functions of insulin are to increase
  ক

  Glucose transport in adopocytes

  খ

  Synthase activity

  গ

  Lipoprotein lipase activity

  ঘ

  Glucose-6-phosphatase activity

  ঙ

  Hormone sensitive lipase activity
• Insulin
  ক

  Is essential for treatment of ketoacidosis

  খ

  Acts by binding to receptors on the cell membrane

  গ

  Can be administered orally

  ঘ

  Is essential for treatment of type II diabetes mellitus

  ঙ

  Is secreted by p-cells of islets of Langerhans of the pancreas
• Functions of insulin are to increase activity of
  ক

  Glucokinase

  খ

  Glycogen synthase

  গ

  Lipoprotein lipase

  ঘ

  Glucose-6-phosphatase

  ঙ

  Hormone sensitive lipase