Developmental anomalies MCQ 4+

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• Non-closure of neuropore leads to
  ক

  Anencephaly

  খ

  Rachischisis

  গ

  Spina bifida

  ঘ

  Omphalocele

  ঙ

  Gastoschisis
• Factors responsible for neural tube defect are
  ক

  Infant of diabetic mother

  খ

  Folate deficiency

  গ

  Failure of migration of neural crest cell

  ঘ

  Zinc deficiency

  ঙ

  Magnesium deficiency
• Neural tube defect
  ক

  May occur due to environmental causes

  খ

  Can be prevented by using folic acid

  গ

  Usually involves the parts of the peripheral nervous system

  ঘ

  Starts during the third month of pregnancy

  ঙ

  Is diagnosed by invasive prenatal testing
• Myelomeningocele is associated with
  ক

  Folate deficiency

  খ

  Involvement of lumbosacral region

  গ

  A high risk of hydrocephalus

  ঘ

  Spastic paralysis of lower limbs in lumbosacral involvement

  ঙ

  Minimal neurologic deficit in involvement of upper thoracic and cervical region