Cvs pharmacology MCQ 74+

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• Drugs causing acute pancreatitis are
  ক

  Tamoxifen

  খ

  6-mercaptopurine

  গ

  Tetracycline

  ঘ

  Rifampicin

  ঙ

  Cyclosporine
• Cyclophosphamide may cause following adverse effects
  ক

  Alopecia

  খ

  Bone marrow suppression

  গ

  Hemorrhagic cystitis

  ঘ

  Albuminuria

  ঙ

  Increased appetite
• The following are immunosuppressive drugs
  ক

  Azathioprine

  খ

  Cyclophosphamide

  গ

  Indomethacin

  ঘ

  Oxyprenolol

  ঙ

  Chlorpropamide
• Immunosuppressive drugs are
  ক

  Cyclosporin

  খ

  Azathioprine

  গ

  Steroids

  ঘ

  Cefaclor

  ঙ

  Azithromycin
• Toxicity of cyclosporine are
  ক

  Hyperkalaemia

  খ

  Hypertension

  গ

  Nephrotoxicity

  ঘ

  Poor wound healing

  ঙ

  Hepatitis
• Anti-fibrinolytic drugs include
  ক

  Aprotinine

  খ

  Tranexamic acid

  গ

  Heparin

  ঘ

  Desmopressin

  ঙ

  Warfarin
• Thrombolytic agents are
  ক

  Streptokinase

  খ

  Urokinase

  গ

  Aspirin

  ঘ

  Clopidegrol

  ঙ

  Warfarin
• Streptokinase is contraindicated in
  ক

  Recent intracranial hemorrhage

  খ

  Chronic renal failure

  গ

  Past history of peptic ulcer bleeding

  ঘ

  NSTEMI

  ঙ

  Hypertension
• Pharmacological effect of aspirin include
  ক

  Inhibition of cyclo-oxygenase enzyme

  খ

  Vasodilatation

  গ

  Chemotaxis

  ঘ

  Phagocytosis

  ঙ

  Leukocyte emigration
• Low dose Aspirin
  ক

  Inhibits the enzyme Thromboxane A2

  খ

  Has anti inflammatory effect

  গ

  Prolongs Prothrombin time

  ঘ

  Is indicated in arrhythmic patients

  ঙ

  Inhibis Prostacycline synthesis
• Drugs inhibit platelet aggregation includes
  ক

  Abciximab

  খ

  Dipyridamole

  গ

  Heparin

  ঘ

  Streptokinase

  ঙ

  Prostacyclin
• Anti-platelet drugs include
  ক

  Clopidogrel

  খ

  Low dose aspirin

  গ

  Abciximab

  ঘ

  Streptokinase

  ঙ

  Enoxaparin
• Drugs preventing platelet aggregation are
  ক

  Clopidogrel

  খ

  Ticlopidine

  গ

  Low dose aspirin

  ঘ

  Warfarin

  ঙ

  Streptokinase
• Indications for warfarin anticoagulation include
  ক

  Venous thromboembolism

  খ

  Arterial embolism

  গ

  Myocardial infarction

  ঘ

  Atrial fibrillation

  ঙ

  Mechanical prosthetic heart valves
• Heparin, a parenteral anticoagulant
  ক

  Increases the activity of antithombin

  খ

  Can cause hypersensitivity reactions

  গ

  Causes bleeding that can be reversed by protamine sulphate

  ঘ

  Increases prohrombin time

  ঙ

  Crosses the placental barrier and causes fetal bleeding
• Heparin:
  ক

  Is a strongly negatively charged organic acid

  খ

  Toxicity is antagonized by protamine sulphate

  গ

  Is obtained synthetically from laboratory source

  ঘ

  Therapy is monitored by activated partial thromboplastin time

  ঙ

  Acts by inhibiting the enzyme epoxide reductase
• Recognized adverse effects of heparin therapy
  ক

  Osteoporosis

  খ

  Alopecia

  গ

  Thrombocytopenia

  ঘ

  Diarrhoea

  ঙ

  Fetal anomalies
• Heparin
  ক

  Prevents clot formation

  খ

  Is used as anticoagulant

  গ

  Is released from the mast cell

  ঘ

  Is a strong acid

  ঙ

  Has a long half life
• Drugs that inhibit the function of oral anticoagulants are
  ক

  Barbiturates

  খ

  Oral contraceptives

  গ

  Cimetidine

  ঘ

  Allopurinol

  ঙ

  Rifampicin
• Following drugs are anticoagulants
  ক

  Lepirudin

  খ

  Enoxaparin

  গ

  Dalteparin

  ঘ

  Urokinase

  ঙ

  Streptokinase
• Followings are anticoagulants
  ক

  Warfarin

  খ

  Aspirin

  গ

  Clopidegrol

  ঘ

  Unfractionated heparin
• The following statements are true about anticoagulants
  ক

  Heparin directly potentiates antithrombin III

  খ

  Osteoporosis may occur due to prolong therapy of Heparin

  গ

  Anticoagulants are contraindicated in major surgery within 10 days

  ঘ

  Monitoring of heparin is done by prothrombin time

  ঙ

  Warfarin can be safely given in pregnancy
• The antiarrythmic property of the following drugs are due to blockade of Na + channels
  ক

  Lidocaine

  খ

  Quinidine

  গ

  Amiodarone

  ঘ

  Sotalol

  ঙ

  Verapamil
• The benefits of dopamine infusion in cardiogenic shock include
  ক

  A rise in the cardiac output

  খ

  Vasodilatation in the renal blood vessels

  গ

  A rise in the diastolic blood pressure

  ঘ

  Slowing of the heart rate

  ঙ

  Vasodilatation in the skeletal blood vessels
• Digoxin toxicities are manifested as
  ক

  Vomiting

  খ

  Bradycardia

  গ

  Ventricular tachycardia

  ঘ

  Headache

  ঙ

  Hypertension
• Heart rate can be increased in a case of heart block following treatment with:
  ক

  Dopamine

  খ

  Isoprenaline

  গ

  Atropine

  ঘ

  Digoxin

  ঙ

  Noradrenaline
• An increase in the heart rate occurs following the therapeutic use of
  ক

  Atropine

  খ

  Dopamine

  গ

  Isoprenaline

  ঘ

  Digoxin

  ঙ

  Sotalol
• Inotropic drugs to be used for compromised cardiac function are
  ক

  Dopamine

  খ

  Digoxin

  গ

  Adrenaline

  ঘ

  Ephedrine

  ঙ

  Noradrenaline
• Digoxin toxicity includes
  ক

  Altered color vision

  খ

  Bradycardia

  গ

  Ventricular tachycardia

  ঘ

  Constipation

  ঙ

  Atrial fibrillation
• Drugs increasing survival of patients with heart failure are
  ক

  Carvedilol

  খ

  Angiotensin converting enzyme inhibitors (ACE-

  গ

  Frusemide

  ঘ

  Milrinone

  ঙ

  Digoxin