Cell injury reversible/ irreversible MCQ 9+

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• Irreversible cell injury is associated with
  ক

  Extensive damage to cellular membranes

  খ

  Swelling of lysosomes

  গ

  Vacuolization of mitochondria

  ঘ

  Dilation of endoplasmic reticulum

  ঙ

  Decreased Cytosolic Ca++
• In irreversible cell injury there is
  ক

  Cell membrane damage

  খ

  ATP depletion

  গ

  Decreased protein synthesis

  ঘ

  Increased pH

  ঙ

  Shrinkage of endoplasmic reticulum
• Hypoxic cell injury leads to
  ক

  Reduced pH

  খ

  Swelling of the endoplasmic reticulum

  গ

  Chromatin clumping

  ঘ

  Reduced lactic acid

  ঙ

  Influx of potassium
• ATP depletion in cell leads to
  ক

  Increased intracellular Na+

  খ

  Increased rate of anaerobic glycolysis

  গ

  Increased intracellular Ca2+

  ঘ

  Increased intracellular K+

  ঙ

  Increased intracellular pH
• Ultrastructural changes of reversible cell injury include
  ক

  Loss of microvilli in plasma membrane

  খ

  Detachment of polysomes from endoplasmic reticulum

  গ

  Appearance of intracytoplasmic myelin figures

  ঘ

  Condensation of nuclear chromatin

  ঙ

  Appearance of translucent areas in mitochondria
• Characteristics of reversible cell injury are
  ক

  Hydropic change

  খ

  Fatty change

  গ

  Intracytoplasmic myelin figures

  ঘ

  Increased basophilia of cytoplasmi

  ঙ

  Breakdown of plasma membrane
• Cellular responses to injury are
  ক

  Necrosis

  খ

  Fatty change

  গ

  Calcification

  ঘ

  Hyperplasia

  ঙ

  Neoplasia
• Morphological changes in reversible cell injury are
  ক

  Swelling of endoplasmic reticulum

  খ

  Amorphous densities in mitochondria

  গ

  Breakdown of plasma membrane

  ঘ

  Formation of lipid vacuoles

  ঙ

  Leakage of cell contents
• Cell injury occurs due to
  ক

  Influx of Na+ and H20 in the cell

  খ

  Increased production of reactive oxygen species

  গ

  Detachment of ribosome

  ঘ

  Increased oxidative phosphorylation

  ঙ

  Influx of K+ in the cell