Blood MCQ 129+

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• Following fluids are used during plasma exchange
  ক

  Hydroxyethyl starch

  খ

  Fresh frozen plasma

  গ

  5% albumin

  ঘ

  Normal saline

  ঙ

  Platelet rich plasma
• Effects of lead poisoning in children are
  ক

  Impaired peripheral nerve function

  খ

  Encephalopathy

  গ

  Nephrotoxicity

  ঘ

  Decreased level of erythrocyte protoporphyrin

  ঙ

  Increased vitamin D metabolism
• Specific gravity of blood increases in
  ক

  Cholera

  খ

  Burn

  গ

  Gastroenteritis

  ঘ

  Plasma pheresis

  ঙ

  5% glucose infusion
• Macrocytes may present in
  ক

  Alcoholism

  খ

  Aplastic anaemia

  গ

  Hypothyroidism

  ঘ

  Myelodysplastic syndrome

  ঙ

  Haemoblobinopathies
• Feature/s of Bartters syndrome is/are
  ক

  Deficiency of urinary acidification

  খ

  Hypomagnessemia

  গ

  Hypercalciurea

  ঘ

  Hypertension

  ঙ

  Metabolic acidosis
• Iron deficiency anaemia is associated with
  ক

  Low MCV

  খ

  Decreased serum iron

  গ

  Increased serum ferritin

  ঘ

  Low total iron binding capacity

  ঙ

  Decreased RDW-CV than normal range
• In iron deficiency anemia
  ক

  Serum iron is reduced

  খ

  Total iron binding capacity increased

  গ

  RDW is reduced

  ঘ

  Serum ferritin is increased

  ঙ

  Nucleated RBC are abundant in peripheral blood film
• Antibodie(s) responsible for immediate haemolytic transfusion reaction is (are)
  ক

  Anti-A

  খ

  Anti-K

  গ

  Anti-JKa

  ঘ

  Anti-H

  ঙ

  Anti-Fyb
• Target cells appear in peripheral blood film in
  ক

  Thalassemia

  খ

  Iron deficiency anemia

  গ

  Sickle cell anemia

  ঘ

  Aplastic anemia

  ঙ

  Pernicious anemia
• RBCs remain separate from each other in the circulating blood due to the repulsive force caused by
  ক

  Constant movement of RBCs

  খ

  Negative electrostatic charge imparted by sialic acid of RBC membrane

  গ

  Attraction of vascular endothelium

  ঘ

  Distraction of band 3 protein

  ঙ

  Biconcave-shape
• In intrinsic pathway of coagulation cascade there is
  ক

  Prolong activated partial thromboplastim time (aPT

  খ

  Prolong clotting time (C

  গ

  Normal platelet

  ঘ

  Prolong prothombin time (P

  ঙ

  Prolong bleeding time (B
• Causes of macrocytosis are
  ক

  Liver disease

  খ

  Use of haematinic

  গ

  Uraemia

  ঘ

  Thalassaemia minor

  ঙ

  New born baby
• RBC stored for 15 days at 40C in CPD solution causes
  ক

  Fall of 2

  খ

  3-DPG

  গ

  Loss of viability

  ঘ

  Rise of PH

  ঙ

  Rise of ATP

  চ

  Loss of potassium & gain of sodium
• Storage temperature of blood are
  ক

  Whole blood +2 to +8°C

  খ

  Red cell concentrate +2 to +8°C

  গ

  Fresh frozen plasma -30 to - 8°

  ঘ

  Platelet concentrate +2 to +5OC

  ঙ

  Granulocyte concentrate +2 to +80C
• After 7 days of storage at doc, blood shows a decrease in concentration of
  ক

  Dextrose

  খ

  Platelets

  গ

  Factors VII

  ঘ

  VIII and XI

  ঙ

  Lactic acid

  চ

  Plasma K+
• Massive transfusion of stored blood risks are
  ক

  Impaired supply of oxygen to tissue

  খ

  Hypercalcaemia

  গ

  Myocardial impairment

  ঘ

  ARDS

  ঙ

  Hypercoagulability
• Prolonged storage of whole blood without preservative leads to
  ক

  Decrease blood glucose level

  খ

  Increase serum potassium level

  গ

  Increase PCO2

  ঘ

  Increase lactate level

  ঙ

  Decrease non-functional plasma enzymes
• 12 hours following acute blood loss one would expect the following results in the patients full blood count A,
  ক

  Raised reticulocyte count

  খ

  Fall in haematocrit

  গ

  Reduced mean corpuscular volume

  ঘ

  Low platelets count

  ঙ

  Low white cell count
• Hypochromic microcytic anemia is a recognised finding in
  ক

  Beta-thalassemia

  খ

  Anemia due to acute blood loss

  গ

  Myelodysplastic syndrome

  ঘ

  Hypothyroidism

  ঙ

  Aplastic anemia
• Thalassaemia major
  ক

  Is a hereditary disease

  খ

  Can be diagnosed by hemoglobin electrophoresis

  গ

  Patients rarely survive beyond 5 years without treatment

  ঘ

  Is due to pathology in chromosome 16

  ঙ

  Incurable
• 110 Direct Coomb's test may be positive in
  ক

  Hemolytic transfusion reaction

  খ

  Drug induced hemolytic reaction

  গ

  Anaphylactic shock

  ঘ

  Massive blood transfusion

  ঙ

  Febrile non hemolytic transfusion reaction
• Haemoglobinuria occurs
  ক

  In black water fever

  খ

  After strenuous exercise

  গ

  Following excessive ingestion of beet root

  ঘ

  Following extensive superficial burns

  ঙ

  During blood transfusion
• Coombs test is positive in
  ক

  ABO incompatibility

  খ

  Systemic lupus erythematosus

  গ

  Hemolytic anemia

  ঘ

  Hemophilia

  ঙ

  Hepatocellular disease
• Coomb's test is positive in
  ক

  Autoimmune hemolytic anemia

  খ

  Transfusion reaction

  গ

  Cold agglutinin disease

  ঘ

  Mismatched blood transfusion

  ঙ

  Hemophilia
• Feature/s of intravascular haemolysis is/are
  ক

  Jaundice

  খ

  Haemosidenuria

  গ

  Reticulocytosis

  ঘ

  Haematuria

  ঙ

  Spherocytosis in peripheral blood film
• Beta thalassemia major
  ক

  Produces hepatosplenomegaly

  খ

  Is associated with extra medullary hemopoiesis

  গ

  Presents with anemia at birth

  ঘ

  Produces a macrocytic anemia

  ঙ

  Rarely requires blood transfusion
• Leucoerythroblastic blood picture can be found in
  ক

  Metastatic carcinoma

  খ

  Haemolytic anemia

  গ

  Mycosis fungoides

  ঘ

  Subleukaemic leukemia

  ঙ

  Thrombotic thrombocytopenic purpura
• Features of hemolytic anemia include
  ক

  Increased reticulocyte count

  খ

  Reduced haptoglobin

  গ

  Raised LDH

  ঘ

  Microcytic blood Picture

  ঙ

  Increased conjugated bilirubin
• Causes of neutropenia include
  ক

  Aplastic anemia

  খ

  Daunorubicin

  গ

  Congenital

  ঘ

  Chronic myeloid leukemia

  ঙ

  Idiopathic thrombocytopenic purpura
• Following enzyme deficiency leads to hemolytic anaemia
  ক

  Pyruvate kinase

  খ

  Glucose 6-phosphate dehydrogenase

  গ

  Lactate dehydrogenase

  ঘ

  Pyruvate dehydrogenase complex

  ঙ

  NADPH oxidase