Biotransformation MCQ 7+

Test your knowledge with important Biotransformation MCQ and their applications. These MCQs are beneficial for competitive exams too. Explore 37+ more Biotransformation MCQs on Bissoy. Bissoy App

• Which of the following drugs are made more active by metabolism?
  ক

  Senna

  খ

  Levodopa

  গ

  Cortisone

  ঘ

  Procaine

  ঙ

  Thiopentine
• Purpose of using prodrug is to modify
  ক

  Absorption of the drug

  খ

  Duration of action of the drug

  গ

  Adverse effects of the drug

  ঘ

  Distribution of the drug

  ঙ

  Biotransformation of the drug
• Prodrugs are
  ক

  Levodopa

  খ

  Azathioprine

  গ

  Sulfazalazine

  ঘ

  Paracetamol

  ঙ

  Frusemide
• Conjugation of drugs with glucuronic acid
  ক

  Produces substances that have greater water solubility

  খ

  Leads to the formation of inactive metabolites

  গ

  Leads to the formation of active metabolites

  ঘ

  Is enhanced in newborn

  ঙ

  Leads to prolongation of drug action
• Conjugation of drugs
  ক

  Occurs primarily in the liver

  খ

  Increases their water solubility

  গ

  Can occur with glucuronic acid

  ঘ

  Is brought about by enzymes present in the intestine

  ঙ

  Does not occur with glycine
• Drugs metabolized by acetylation are
  ক

  Hydralazine

  খ

  Isoniazide

  গ

  Procainamide

  ঘ

  Diazepam

  ঙ

  Naproxen
• Biotransformation of a drug
  ক

  c. May produce active metabolites

  খ

  d. May produce toxic metabolites

  গ

  Reduces its water solubility

  ঘ

  b. Increases its lipid solubility

  ঙ

  e. May prolong the plasma half-life (t 1/2) of the drug