Basic Principles Of Biotechnology MCQ
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Which of the following equation represent the reciprocal of Michaelis-Menten equation
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A protein which spans that lipid bilayer
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Telomerase activity was monitored in the following cell types. The highest amount of telomerase activity was found in the combination of
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Cytochrome P450 family of enzymes causes detoxification mainly by
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In a bioreactor baffles are incorporated to
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The concept of random fluctuations gene frequency as an evolutionary force was originally proposed by
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All histones undergo post-translational modification of specific amino acids. These modifications<br>P. Alter the charge of the histone molecule<br>Q. Are permanent<br>R. Occur on the N-terminal tail of the histones, which are thought to extend out from the core<br>S. Occur at specific times during the cell cycle
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In mammalian cells, RNA editing<br>P. Can change the coding capacity of a gene after transcription<br>Q. Creates a stop codon in the middle of the apo-B mRNA in intestinal cells but not in liver cells<br>R. Usually makes many changes in each mRNA<br>S. Can change specific nucleotides by deamination
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Binding of mannose 6-Phosphate to protein lead to its localization to
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In the meiosis type cell division, chromatids segregates during
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Power number also called Newton's number, is defined as a dimensionless parameter relating to
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If the frequency of males affected with an X-linked recessive condition in a human population is 0.10 (one in ten), what will be the expected frequency of affected females?
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Shear stress versus shear rate behavior of four different types of fluids (I, II, III and IV) are shown in the figure below.<br><img src="/images/question-image/biotechnology-engineering/basic-principles-of-biotechnology/1678951848-shear-stress-versus-shear-rate-behavior-of-four.jpg" title="Basic Principles of Biotechnology mcq question image" alt="Basic Principles of Biotechnology mcq question image"><br>Which one of the following options is correct?
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Glycogen is a branched polymer of glucose It has
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In a well aerated and agitated microbial culture, the 'supply' of oxygen is equal to 'demand' (uptake) of the growing culture. The K<sub>L</sub>a for such a system will be (K<sub>L</sub>a = volumetric mass transfer coefficient, C* = dissolved oxygen concentration in liquid in equilibrium with gaseous oxygen, C = instantaneous value of dissolved oxygen concentration, 'r' = specific oxygen uptake rate per unit weight of cells, X = dry weight of the cells per unit volume)
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Measurement of K<sub>L</sub>a in a bioreactor can be carried out by sodium sulfite oxidation method, that is, based on the oxidation of sodium sulfite to sodium sulfate in the presence of a catalyst (Cu<sup>++</sup> or Co<sup>++</sup>). In a typical experiment, a laboratory fermenter was filled with 5 liter of 0.5 M sodium sulfite solution containing 0.003 M Cu<sup>++</sup> ions and the air was sparged in. After 10 min, the air flow was stopped and a 10 mL sample was taken and titrated. The concentration of sodium sulfite in the sample was found to be 0.20 M. The oxygen uptake rate for this aerated system will work out to be
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Phase contrast microscope takes advantage of
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X-ray crystallography are<br>P. Based on the elastic scattering of X-rays<br>Q. Non-destructive analytical techniques<br>R. Used in determining the arrangement of atoms within a crystal<br>S. Based on Bragg's law
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A multiple cloning site
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Which of the following Chemotherapeutic agents works by impairing de novo synthesis?
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Microsatellites are used more commonly than minisatellite as DNA markers because
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Which of the following statements about histones is incorrect?
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Which of the following statements about myosin is not true?
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Which one of the following is the most suitable type of impeller for mixing high viscosity (viscosity > 10<sup>5</sup> cP) fluids?
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Which of the following statements are true in case of fluid-mosaic model for cell membrances<br>P. Between 5 - 8 nm thick and appear trilaminar when viewed in cross-section under electron microscope<br>Q. Less than 1 nm thick and consist of a layer of protein sandwitched between two layers of phospholipids<br>R. In the lipid bilayer, proteins are embedded at irregular intervals and held by hydrophilic interactions between lipids and hydrophilic domains of the proteins<br>S. The protein domains exposed on one side of the lipid bilayer are different from those exposed on the other side
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Amplified fragment length polymorphism (AFLP)<br>P. A PCR-based tool<br>Q. Uses restriction enzymes to cut genomic DNA<br>R. Involves ligation of adaptors to the sticky ends of the restriction fragments<br>S. Involves amplification using primers complementary to the adaptor
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Which one of the following is the unit of heat transfer coefficient?
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In the RNAi regulatory pathway, the DICER enzyme cleaves
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A homogeneous protein of native molecular weight 100,000 gave a single band of molecular weight 50,000 on SDS-PAGE in presence of β-mercaptoethanol. N-terminal analysis gave two amino acids alanine and leucine in equal proportions. Hence the
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For a nucleic acid probe to hybridize, which of the following must be true?