Administration of general anesthetics decreases the presynaptic Ca2+ entry.

Administration of general anesthetics decreases the presynaptic Ca2+ entry. Correct Answer True

Administration of general anesthetics decreases the presynaptic Ca2+ entry, thus decreases the neurotransmitter release. It increases postsynaptic Cl– entry and also increases postsynaptic K+ leakage from the cell. Local anesthetics help block conduction. It decreases the axonal Na+ entry thus prevents action potential propagation.
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