Which of the following is wrong?
A
Site specific recombination between two linear chromosomes result in exchange of segment
B
Site specific recombination between two circular chromosomes will result in insertion
C
Site specific mutation in one linear molecule will lead to excision
D
For recombination to take place recombinase is a must
Correct Answer: Site specific mutation in one linear molecule will lead to excision
Although site specific mutation in one linear molecule can lead to excision, this is not the only case. It can also lead to inversion of the flanking sequence if the surrounding segments are in opposite symmetry.