Cyclin dependent kinases which control progression through cell cycle checkpoints are totally activated by which of the following?

Cyclin dependent kinases are activated by which of the following?

A

Binding to cyclin

B

Binding to cyclin and CDK activating protein kinases

C

Phosphorylation with CDK activating kinase

D

Phosphorylation with tyrosine kinase

Which of the following is wrong about the cyclin dependent kinases?

A

Phosphorylates enzymes

B

Activates pre – RCs

C

Promotes formation of new pre – RCs

D

Activates in the S – phase

Which ions activate cyclin-dependent kinases, following fertilization?

A

Ca2+

B

Mg2+

C

Fe3+

D

H+

Which of the following is/are the advantages of using a control chart for inspection? (i) A control chart indicates whether the process is in control or out of control. (ii) A control chart determines process variability. (iii) A control chart ensures product quality. (iv) Scrap or percentage reduction can be reduced by taking the necessary actions in time against the warnings indicated by control charts. (v) Control charts build up the reputation of the organization through customer’s satisfaction. (vi) The control chart can detect the unusual variations taking place in a process.

A

i, ii, iii only

B

i, iv, v only

C

i, ii, iii, iv, v and vi

D

iv, v and vi

Cyclin-CDK complex (here considering S cyclin) when active is responsible for phosphorylating several proteins and this often marks then for destruction by ubiquitination. What would be its effect on Cdt activity?

A

Activation

B

Inactivation

C

Destruction

D

Increased synthesis

Which of the following statements are correct about eukaryotic cell cycle?
P. CDKs can phosphorylate proteins in the absence of cyclins.
Q. CDKs can be inactivated by phosphorylation.
R. Degradation of cyclins is required for cell cycle progression.
S. CDKs are not involved in chromosome condensation.

A

P and R only

B

P and S only

C

P, Q and R only

D

Q and R only

M cyclin cdk is activated by positive feedback loop.

A

True

B

False

In the course of cell cycle, the level of the protein cyclin abruptly falls during

A

G₁ phase

B

S phase

C

G₂ phase

D

M phase

The cytoplasmic protein-tyrosine kinases are activated indirectly by the extracellular signals.

A

True

B

False

Which of the following statements regarding cyclin-dependent protein kinase is not correct?

A

Their activity is regulated by cyclins

B

They can alter the activity of proteins involve in the progression of cells through cell cycle

C

Their activity fluctuates during cell cycle

D

Each type of cell contains one specific form e) Their activity is regulated by changes in gene expression, protein phosphorylation and proteolysis

Cyclin dependent kinases which control progression through cell cycle checkpoints are totally activated by which of the following?

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