Medical Post Graduation | Pharmacology | Endocrine pharmacology

Practice Medical Post Graduation | Pharmacology | Endocrine pharmacology on Bissoy — browse topics below and open any question.

Questions

Drugs causing hypothyroidism are

ক

Lithium

খ

Amiodarone

গ

Iodopaque

ঘ

Digoxin.

ঙ

Thalidomide

Metformin causes

ক

Gastrointestinal upset

খ

Lactic acidosis

গ

Hypoglycemia

ঘ

Impaired kidney function

ঙ

Weight gain

Anti-diabetic drugs reducing body weight are

ক

SGLT-2 inhibitors

খ

GLP-1 analogues

গ

Thiazolidinediones

ঘ

Metformin

ঙ

DPP-4 inhibitors

Drugs causing hyperglycaemia are

ক

Thiazides

খ

Diazoxide

গ

Theophylline

ঘ

Nitroglycerine

ঙ

Prazosine

Side-effects of insulin therapy are

ক

Hypoglycemia

খ

Weight gain

গ

Hypertension

ঘ

Hyperkalemia

ঙ

Chronic renal failure

Linagliptin

ক

Lowers blood glucose in type ii diabetes

খ

Causes hypoglycemia

গ

Is contraindicated in renal failure

ঘ

Is a GLP analogue

ঙ

Is an incretin like hormone

Euglycaemic anti-diabetic drugs are

ক

Metformin

খ

Pioglitazone

গ

Glipizide

ঘ

Tolazamide

ঙ

Glyburide

The following statements about Pharmacotherapy of Diabetes Mellitus are correct:

ক

Insulin therapy is always associated with some degree of hypoglycaemia.

খ

Resistance against human Insulin is best treated by changing to bovine insulin.

গ

Pregnant diabetic patients are best treated by Biguanides because they are not teratogenic.

ঘ

Human insulin best therapeutically because of lesser chance of hypoglycaemia.

ঙ

Î±-glucosidase-inhibitor therapy is equally effective as Sulphonylurea drug in NIDDM.

Statement about hypoglycaemic agents include:

ক

Glipizide produces less hypoglycemia compared to Glibenclamide

খ

Pioglitazone may provoke cardiac congestion

গ

Metformin increases hepatic glucose out put

ঘ

Repaglinide is euglycemic

ঙ

Insulin glargine is shorter

চ

acting than isophane insulin

Sulfonylureas

ক

Increase the secretion of insulin by Î²-cells

খ

Decrease serum glucagon

গ

Exhibit high affinity for plasma protein binding 99%

ঘ

Decrease the number of insulin receptors

ঙ

Can be used in renal disease

The beneficial effects of metformin are:

ক

Reduction hepatic glucose production

খ

Rarely hypoglycaemia or weight gain

গ

Increasing the number of insulin receptors

ঘ

Used in combination with sulfonylurea

ঙ

Stimulation insulin secretion

Adverse effects of metformin are

ক

Lactic acidosis

খ

Abdominal discomfort

গ

Diarrhoea

ঘ

Weight gain

ঙ

Hypoglycamia

Glucocorticoids having high anti-inflammatory action are

ক

Dexamethasone

খ

Prednisolone

গ

Hydrocortisone

ঘ

Beclomethasone

ঙ

Prednisone

Glucocorticoids

ক

Are anti-inflammatory drugs

খ

Produce peptic ulcer

গ

Are essential for treatment of Addisonâs disease

ঘ

Are effective in the treatment of bronchial asthma

ঙ

Produce effect by binding to receptors on the cell membrane

Glucocorticoids are useful in the treatment of

ক

Ulcerative colitis

খ

Acute leukaemia in children

গ

Peptic ulcer

ঘ

Psychosis

ঙ

Cushing's disease

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