Dextromethorphan + Pseudoephedrine + Triprolidine

Introduction

Dextromethorphan + Pseudoephedrine + Triprolidine (brand name, TriProfed) is a combination of three drugs used to treat symptoms of the common cold, flu, allergies, and other non-life-threatening conditions. It combines a cough suppressant (dextromethorphan), a decongestant (pseudoephedrine), and an antihistamine (triprolidine) to provide relief of nasal and chest congestion, coughing, and runny nose.

Uses

Dextromethorphan + Pseudoephedrine + Triprolidine is used to treat congestion symptoms associated with colds, flu, allergies, or other non-life-threatening conditions. It can help to reduce coughing, runny nose, and chest congestion.

Brand Name	Dextromethorphan + Pseudoephedrine + Triprolidine
Type
Weight
Generic	Dextromethorphan + Pseudoephedrine + Triprolidine
Manufacturer
Available in	English বাংলা

Mechanism of Action

Dextromethorphan is a cough suppressant. It helps to reduce coughing by acting on the cough center of the brain. Pseudoephedrine is a decongestant. It helps to reduce nasal congestion by narrowing the blood vessels in the nasal passages. Triprolidine is an antihistamine. It helps to reduce symptoms of allergies by blocking the effects of histamine, a substance released during an allergic reaction.

How Long Does it Take to Work?

Typically, Dextromethorphan + Pseudoephedrine + Triprolidine begins to work within 30 minutes of administration. The effects may last up to 8 hours.

Absorption

The active ingredients of Dextromethorphan + Pseudoephedrine + Triprolidine are rapidly absorbed through the gastrointestinal tract into the bloodstream.

Route of Elimination

The active ingredients of Dextromethorphan + Pseudoephedrine + Triprolidine are mainly excreted through urinary and fecal routes.

Dosage

Adults & Children over 12 years: 1 teaspoonful (5 ml) 4 times a day every 4 hours interval.

6-12 years: 1/2 teaspoonful 4 times a day every 4 hours interval.

Use in children and adolescents: A physician's advice should be obtained before administering this combination to children less than 6 years. The recommended dosage of Dextromethorphan + Pseudoephedrine + Triprolidine depends on the age, weight, and condition of the patient. For adults and children 12 years and older, the recommended dose is one tablet every 4 to 6 hours, not to exceed 5 tablets in 24 hours. For children aged 4 to 11 years, the recommended dose is one-half to one tablet every 4 to 6 hours, not to exceed 2 tablets in 24 hours.

Administration

Dextromethorphan + Pseudoephedrine + Triprolidine is available in an oral tablet form. It should be taken by mouth with a glass of water.

Side Effects

The most common side effects of Dextromethorphan + Pseudoephedrine + Triprolidine include drowsiness, headache, dry mouth, nausea, vomiting, dizziness, and constipation.

Toxicity

At recommended dosages, Dextromethorphan + Pseudoephedrine + Triprolidine is generally safe and well tolerated. Overdose of Dextromethorphan + Pseudoephedrine + Triprolidine can cause serious and potentially life-threatening side effects. In cases of overdose, medical attention should be sought immediately.

Precautions

Dextromethorphan + Pseudoephedrine + Triprolidine should not be taken by patients with asthma, glaucoma, heart disease, high blood pressure, hyperthyroidism, or urinary retention. It can also interact with certain medications, such as MAO inhibitors, antacids, tricyclic antidepressants, and narcotics. Patients should always consult a doctor prior to taking Dextromethorphan + Pseudoephedrine + Triprolidine .

Interaction

Dextromethorphan + Pseudoephedrine + Triprolidine can interact with certain drugs and supplements, such as MAO inhibitors, antacids, tricyclic antidepressants, narcotics, sympathomimetics, and alcohol. Patients should always consult a doctor prior to taking Dextromethorphan + Pseudoephedrine + Triprolidine and inform the doctor of any drugs or supplements they are taking.

Disease Interaction

Dextromethorphan + Pseudoephedrine + Triprolidine can interact with certain diseases and conditions, such as asthma, glaucoma, heart disease, high blood pressure, hyperthyroidism, and urinary retention. Patients should always consult a doctor prior to taking Dextromethorphan + Pseudoephedrine + Triprolidine and inform the doctor of any underlying health condition they may have.

Drug Interactions

Dextromethorphan + Pseudoephedrine + Triprolidine can interact with certain drugs, such as MAO inhibitors, antacids, tricyclic antidepressants, and narcotics. Patients should always consult a doctor prior to taking Dextromethorphan + Pseudoephedrine + Triprolidine and inform the doctor of any medications they are taking.

Food Interactions

Dextromethorphan + Pseudoephedrine + Triprolidine can interact with certain foods, such as dairy products, antacids, tricyclic antidepressants, and narcotics. Patients should always consult a doctor prior to consuming these foods while taking Dextromethorphan + Pseudoephedrine + Triprolidine .

Pregnancy Use

Dextromethorphan + Pseudoephedrine + Triprolidine is a Category C drug, meaning its safety during pregnancy has not been established. It should be used during pregnancy only if clearly needed. Patients should consult their doctor about potential risks before taking Dextromethorphan + Pseudoephedrine + Triprolidine during pregnancy.

Lactation Use

It is not known whether Dextromethorphan + Pseudoephedrine + Triprolidine is excreted in human milk. Patients should consult their doctor before taking Dextromethorphan + Pseudoephedrine + Triprolidine while breastfeeding.

Acute Overdose

Overdose of Dextromethorphan + Pseudoephedrine + Triprolidine can cause serious and potentially life-threatening side effects. If an overdose is suspected, medical attention should be sought immediately.

Contraindications

Dextromethorphan + Pseudoephedrine + Triprolidine should not be used in patients with hyperthyroidism, glaucoma, prostate enlargement, severe heart disease, or severe arteriosclerosis.

Use Direction

Dextromethorphan + Pseudoephedrine + Triprolidine should be taken orally with a glass of water. It should be taken only as directed. Do not exceed the recommended dose or take for longer than prescribed.

Storage Conditions

Dextromethorphan + Pseudoephedrine + Triprolidine should be stored at room temperature, away from heat and moisture. The tablets should be kept in a tightly closed container.

Volume of Distribution

The volume of distribution of Dextromethorphan + Pseudoephedrine + Triprolidine is not known.

Half Life

The half life of Dextromethorphan + Pseudoephedrine + Triprolidine is not known.

Clearance

The clearance of Dextromethorphan + Pseudoephedrine + Triprolidine is not known.

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Some Frequently Asked Questions About Dextromethorphan + Pseudoephedrine + Triprolidine

1. What is Dextromethorphan + Pseudoephedrine + Triprolidine ?

It is a combination medicine used to relieve symptoms of colds, flu, and allergies, including cough, nasal congestion, and runny nose.

2. What are the active ingredients in this medication?

This drug contains:

• Dextromethorphan: A cough suppressant
• Pseudoephedrine: A nasal decongestant
• Triprolidine: An antihistamine that reduces allergy symptoms

3. What conditions does this medication treat?

It is used to relieve symptoms of:

• Common cold
• Flu
• Allergies
• Sinus congestion
• Post-nasal drip

4. How does Dextromethorphan work?

It suppresses the cough reflex in the brain, reducing dry, non-productive coughs.

5. How does Pseudoephedrine work?

It constricts blood vessels in the nasal passages, reducing swelling and congestion.

6. How does Triprolidine work?

It blocks histamine, reducing allergy symptoms like sneezing, runny nose, and watery eyes.

7. Is this medication available over the counter?

Yes, but some formulations may require a prescription due to the presence of Pseudoephedrine.

8. How should I take this medication?

Take it as directed by your doctor or per the package instructions, usually every 4 to 6 hours.

9. Can I take this medication with food?

Yes, it can be taken with or without food. Taking it with food may help prevent stomach upset.

10. What is the usual adult dosage?

Typically, 10 mL (2 teaspoons) or one tablet every 4-6 hours as needed. Do not exceed the recommended dose.

11. Can children take this medication?

It is not recommended for children under 6 years old without a doctor's advice.

12. What should I do if I miss a dose?

Take the missed dose as soon as you remember. If it's almost time for the next dose, skip the missed one.

13. What happens if I take too much?

Overdose symptoms may include dizziness, confusion, fast heart rate, hallucinations, or seizures. Seek medical help immediately.

14. What are the common side effects?

Common side effects include:

• Drowsiness
• Dizziness
• Dry mouth
• Nausea
• Increased heart rate

15. Can this medication make me drowsy?

Yes, Triprolidine (antihistamine) can cause drowsiness.

16. Can I drive after taking this medication?

Avoid driving or operating heavy machinery if you feel drowsy or dizzy.

17. Can I drink alcohol while taking this medication?

No, alcohol can increase drowsiness and dizziness.

18. Can I take this medication if I have high blood pressure?

Pseudoephedrine may increase blood pressure. Consult your doctor before use.

19. Can I take this if I have diabetes?

Pseudoephedrine may affect blood sugar levels. Diabetics should consult a doctor before use.

20. Can I take this medication while pregnant?

Consult your doctor before using this medication during pregnancy.

21. Can breastfeeding mothers take this medication?

It may pass into breast milk. Consult your doctor before use.

22. Can this medication be taken long-term?

No, it is for short-term use only to relieve symptoms of colds and allergies.

23. Can I take this medication with antibiotics?

Yes, but consult your doctor to avoid possible interactions.

24. Does this medication contain caffeine?

No, but Pseudoephedrine may cause mild stimulation.

25. Can I take this medication if I have asthma?

Consult your doctor, as it may worsen asthma symptoms in some individuals.

26. Can I take it with a sleeping pill?

No, taking it with sedatives can increase drowsiness.

27. Can I take this medication for COVID-19 symptoms?

It may help relieve some symptoms like cough and congestion but does not treat COVID-19.

28. Does this medication help with a sore throat?

It may relieve throat irritation from coughing but does not treat bacterial infections.

29. Can I take this medication with ibuprofen?

Yes, but always follow your doctor’s recommendations.

30. Can I take this medication with paracetamol?

Yes, it can be taken with paracetamol if needed for fever or pain.

31. Does this medication cause insomnia?

Pseudoephedrine may cause trouble sleeping in some people.

32. Can I take this medication if I have thyroid problems?

Consult your doctor, as Pseudoephedrine may affect thyroid hormone levels.

33. Can this medication cause dry eyes?

Yes, it may reduce tear production, causing dry eyes.

34. Does this medication contain steroids?

No, it does not contain steroids.

35. Can this medication be addictive?

No, but overuse can cause dependency on the decongestant effects.

36. Can I take this medication with antihistamines?

Check the ingredients, as it already contains Triprolidine (an antihistamine).

37. Does this medication interact with antidepressants?

Yes, it may interact with MAO inhibitors and SSRIs. Consult your doctor before use.

38. Can I give this medication to my pet?

No, it is not meant for animals.

39. Can I take this medication with a decongestant nasal spray?

Avoid combining decongestants unless advised by a doctor.

40. Does this medication expire?

Yes, do not use expired medication.

41. How should I store this medication?

Store at room temperature, away from moisture and heat.

42. Can I take it if I have glaucoma?

Consult your doctor, as antihistamines can increase eye pressure.

43. Can it be taken for sinus infections?

It may help with congestion, but it does not treat bacterial sinus infections.

44. Can it be taken for allergic rhinitis?

Yes, it can help with allergy symptoms.

45. Can this medication cause weight gain?

Weight gain is not a common side effect.

46. Does this medication increase heart rate?

Pseudoephedrine may cause a slight increase in heart rate.

47. Can I take it with cough syrup?

Avoid taking multiple cough medicines to prevent overdose.

48. Is it safe for elderly patients?

Elderly patients should use it with caution due to potential side effects.

49. Can this medication cause stomach upset?

Yes, take it with food if it causes discomfort.

50. Can this medication be used for bronchitis?

It may help with symptoms, but does not cure bronchitis.