Specific Scoring Matrices MCQ

Test your knowledge with important Specific Scoring Matrices MCQ and their applications. These MCQs are beneficial for competitive exams too. Explore 30 + more Specific Scoring Matrices MCQs at Bissoy

• Two commonly encountered examples are the Genetics Computer Group’s MSF format and the CLUSTALW ALN format.
  ক

  True

  খ

  False
• MACAW is a local multiple sequence alignment program only.
  ক

  True

  খ

  False
• GDE (Genetic Data Environment) provides a general interface on UNIX machines for sequence analysis, sequence alignment editing, and display.
  ক

  True

  খ

  False
• Which of the following is not a feature of editors and formatters?
  ক

  provision for displaying the sequence on a color monitor with residue colors to aid in a clear visual representation of the alignment

  খ

  recognition of the multiple sequence format that was output by the MSA (Multiple Sequence Alignment) program

  গ

  maintenance of the alignment in a suitable format when the editing is completed

  ঘ

  disallowing shading conserved residues in the alignment
• Even if many pseudocounts are added in comparison to real sequence counts, the amino acid frequencies will not have any effect or influence.
  ক

  True

  খ

  False
• If the data set is _______ then unless the motif has __________ amino acids in each column, the column frequencies in the motif may not be highly representative of all other occurrences of the motif.
  ক

  small, distinct

  খ

  small, almost identical

  গ

  large, almost identical

  ঘ

  large, distinct
• If a good sampling of sequences is _______ the number of sequences is _________ and the motif structure is ________ it should, in principle, be possible to obtain frequencies highly representative of the same motif in other sequences also.
  ক

  available, sufficiently large, not too complex

  খ

  unavailable, sufficiently large, not too complex

  গ

  unavailable, sufficiently small, not too complex

  ঘ

  available, sufficiently large, too complex
• Two considerations arise in trying to tune the PSSM so that it adequately represents the training sequences. Which of the following is not their description?
  ক

  If a given column in 20 sequences has only isoleucine, it is not very likely that different amino acid will be found in other sequences with that motif because the residue is probably important for function

  খ

  If a given column in 20 sequences has only isoleucine, it is very likely that different amino acid will be found in other sequences with that motif because the residue is probably important for function

  গ

  If the number of sequences with the found motif is large and reasonably diverse, the sequences represent a good statistical sampling of all sequences that are ever likely to be found with that same motif

  ঘ

  Another column in the motif from the 20 sequences may have several amino acids, and some amino acids may not be represented at all
• The quality and quantity of information provided by the PSSM also varies for ________ in the motif.
  ক

  each row

  খ

  each column

  গ

  rows and columns

  ঘ

  neither the rows nor the columns
• Analysis of s for conserved blocks of sequence leads to production of the position-specific scoring matrix.
  ক

  True

  খ

  False