Protein Denaturation and Folding MCQ

Test your knowledge with important Protein Denaturation and Folding MCQ and their applications. These MCQs are beneficial for competitive exams too. Explore 30+ more Protein Denaturation and Folding MCQs on Bissoy. Bissoy App

• Which of the following is true about ribonucease?
  ক

  Native state which is catalytically inactive is denatured

  খ

  Unfolded state is inactive

  গ

  Renatured ribonuclease is inactive

  ঘ

  Renaturation involves reestablishment of the correct disulfide cross links
• Protein A will fold into its native state only when protein B is also present in the solution. However, protein B can fold itself into native confirmation without the presence of protein A. Which of the following is true?
  ক

  Protein B serves as precursor for protein A

  খ

  Protein B serves as molecular chaperon for protein A

  গ

  Protein B serves as ligand for protein A

  ঘ

  Protein B serves as structural motif for protein A
• Which of the following about spontaneous folding is false?
  ক

  It involves the initial formation of highly compact structure

  খ

  It involves initial formation of a local secondary structure

  গ

  It is essentially a random process

  ঘ

  It may be defective in some human diseases
• Which of the following are chaperons in E.coli?
  ক

  Hsp70

  খ

  Hsp40

  গ

  DnaA

  ঘ

  DnaK and DnaJ
• As folding progresses which of the following does not take place?
  ক

  Entropy decreases

  খ

  Amount of protein in native state increases

  গ

  Free energy increases

  ঘ

  Amount of protein in native state decreases
• Which of the following cannot denature a protein?
  ক

  Iodoacetic acid

  খ

  SDS detergent

  গ

  Urea

  ঘ

  Heating to 90°C
• Process of folding does not depend on ____________
  ক

  Concentration of salts

  খ

  pH

  গ

  Solute

  ঘ

  Solvent
• A process by which a protein structure assumes its functional shape or conformation is?
  ক

  Denaturing

  খ

  Folding

  গ

  Synthesis

  ঘ

  Hydrolysis
• Which of the following forces is favorable for protein folding?
  ক

  Hydrophobic interactions

  খ

  Hydrogen bonding

  গ

  Vander Waals forces

  ঘ

  Ionic bonding