Phase 1 Reactions -1 MCQ

Test your knowledge with important Phase 1 Reactions -1 MCQ and their applications. These MCQs are beneficial for competitive exams too. Explore 30 + more Phase 1 Reactions -1 MCQs at Bissoy

• What is the function of a flavoprotein, located in the endoplasmic reticulum?
  ক

  Oxidising the substrate

  খ

  Reducing the cytochrome-450 to the ferrous form

  গ

  Facilitate electron transfer from NADPH to cytochrome 450

  ঘ

  Facilitate electron transfer from cytochrome 450 to NADPH
• What is the function of Phosphatidylcholine in multienzyme mixed-function oxidase system, located in the endoplasmic reticulum?
  ক

  Oxidising the substrate

  খ

  Reducing the substrate

  গ

  Facilitate electron transfer from NADPH to cytochrome 450

  ঘ

  Facilitate electron transfer from cytochrome 450 to NADPH
• What are the names of the 3 protein involve in multienzyme mixed-function oxidase system, located in the endoplasmic reticulum?
  ক

  Heme protein, flavoprotein, phosphatidylcholine

  খ

  Heme protein, flavoprotein, retinal protein

  গ

  Heme protein, retinal protein, phosphatidylcholine

  ঘ

  Retinal protein, flavoprotein, phosphatidylcholine
• Following are the Phase I reactions except ____________
  ক

  Oxidative reactions

  খ

  Hydrolytic reactions

  গ

  Reductive reactions

  ঘ

  Sulphide reactions
• Phase 1 reactions are also known as a synthetic reaction.
  ক

  True

  খ

  False
• Where are non-microsomal enzymes present?
  ক

  In the Golgi apparatus

  খ

  Inside lysosomes

  গ

  In the cytoplasm in soluble form

  ঘ

  In oxysomes
• Microsome are selective to ____________
  ক

  Water-soluble drugs

  খ

  Lipid soluble drugs

  গ

  Acidic drugs

  ঘ

  Basic drugs
• The enzymes are divided into two categories, these are _______ and ____________
  ক

  Acidic drug metabolizing and basic drug metabolizing

  খ

  Present in the liver and not present in the liver

  গ

  Microsomal and non-microsomal

  ঘ

  There is no such division
• Which of the following is the correct decreasing order of drug metabolism?
  ক

  Liver > lungs > kidneys > intestine > placenta > skin > adrenals

  খ

  Liver > lungs > kidneys > intestine > adrenals > placenta > skin

  গ

  Liver > kidneys > lungs > intestine > placenta > adrenals > skin

  ঘ

  Liver > lungs > intestine > kidneys > placenta > adrenals > skin
• What are soft drugs?
  ক

  Drugs given to babies

  খ

  Chemical drugs which are already found in the body

  গ

  Nutrients which kill the gut harmful microbes

  ঘ

  Anything that is not nutrients and enters the body through different routes
• What is the inactive form of Codeine?
  ক

  Codene

  খ

  Codane

  গ

  Morphine

  ঘ

  Poppy
• What is the active form of salicylic acid?
  ক

  Sialic acid

  খ

  Salic acid

  গ

  Salicylic acid

  ঘ

  Salicycle acid
• The drug biotransformation is a detoxification process.
  ক

  True

  খ

  False
• What are xenobiotics?
  ক

  Another form of antibiotics

  খ

  A form of nutrient

  গ

  Nutrients which kill the gut harmful microbes

  ঘ

  Anything that is not nutrients and enters the body through different routes
• Biotransformation of drugs is defined as the conversion from one physical form to another.
  ক

  True

  খ

  False