Overview of Protein Synthesis MCQ

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• Which of the following does not take part in stabilizing the cloverleaf model of the tRNA?
  ক

  Base stacking

  খ

  Base and sugar-phosphate backbone interaction

  গ

  Ionic bond

  ঘ

  Hydrogen bond
• The 3 dimension structure of an adaptor molecule of translation is revealed to be ___________
  ক

  Y shaped

  খ

  L shaped

  গ

  K shaped

  ঘ

  X shaped
• The variable loop is found between the ___________
  ক

  Acceptor stem and ΨU loop

  খ

  Acceptor stem and D loop

  গ

  Anticodon loop and ΨU loop

  ঘ

  Anticodon loop and D loop
• How many double helix regions are observed in a tRNA molecule?
  ক

  4

  খ

  3

  গ

  2

  ঘ

  1
• How many loops are seen in the tRNA?
  ক

  1

  খ

  2

  গ

  3

  ঘ

  4
• Dihydrouridine is the result of oxidation of the uracil base.
  ক

  True

  খ

  False
• In pseudouridine the attachment of Uracil base to ribose through ___________ of uracil.
  ক

  N at position 3

  খ

  C at position 6

  গ

  C at position 5

  ঘ

  N at position 1
• The end of all tRNAs is ___________
  ক

  5’ ACC 3’

  খ

  5’ CCA 3’

  গ

  3’ CAC 5’

  ঘ

  3’ GAG 5’
• After bounding to the mRNA eukaryotic ribosome scans the entire mRNA until it encounters a start codon.
  ক

  True

  খ

  False
• Eukaryotic ribosome is recruited to the mRNA by _____________
  ক

  Randomly

  খ

  Shine – Dalgarno sequence

  গ

  5’ capping

  ঘ

  3’ tailing
• The phenomenon of translating two a protein by two ribosomes is known as translational coupling.
  ক

  True

  খ

  False
• Which component of the rRNA binds to the mRNA?
  ক

  16S

  খ

  5S

  গ

  28S

  ঘ

  23S
• Shine – Dalgarno sequence is also known as the __________
  ক

  ORF

  খ

  RBS

  গ

  Stop codon

  ঘ

  Start codon
• Both prokaryotes and Eukaryotes have one ORF.
  ক

  True

  খ

  False
• How many reading frames are applicable in case of translation?
  ক

  1

  খ

  2

  গ

  3

  ঘ

  4
• The start codon has a vital role to play in incorporating the specific amino acids in the peptide chains.
  ক

  True

  খ

  False
• Both Prokaryote and Eukaryote has one start codon 5’-AUG-3’.
  ক

  True

  খ

  False
• Which of the following is not a property of open reading frame?
  ক

  Contiguous

  খ

  Non overlapping

  গ

  Encodes a single protein

  ঘ

  Starts and ends at either end of the mRNA.
• How many major components are used for the process of translation?
  ক

  1

  খ

  2

  গ

  3

  ঘ

  4
• Who was the first to propose indirect interaction between mRNA template and amino acids to produce accurate ordering of amino acid in a polypeptide chain?
  ক

  Paul C. Zamecnic

  খ

  James Watson

  গ

  Francis H. Crick

  ঘ

  Mahlon B. Hoagland
• The accurate ordering of amino acids in a polypeptide is determined by the direct interactions between the mRNA template and the amino acid.
  ক

  True

  খ

  False
• Which of the following is the most energetically costly process among the following?
  ক

  Replication

  খ

  Transcription

  গ

  Post transcriptional processing

  ঘ

  Translation