Motif and Domain Databases Using Regular Expressions MCQ

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• What does this representation mean- R.L.?
  ক

  ? ] An arginine- Amino acid- Leucine- Amino acid- Either Apartic acid, glutamic acid or glutamine

  খ

  EQD

  গ

  EQD

  ঘ

  EQD
• Which of the following is not a characteristic of exact matches in regular expression?
  ক

  There must be a strict match of sequence patterns

  খ

  Any variations in the query sequence from the predefined patterns are not allowed

  গ

  Provide more permissive matching by allowing more flexible matching of residues of similar biochemical properties

  ঘ

  Searching a motif database using this approach results in either a match or non-match
• Which of the following is not a characteristic of Fuzzy or approximate matches in regular expression?
  ক

  This method is able to include more variant forms of a motif with a conserved function

  খ

  the rule of matching is based on observations, not actual assumptions

  গ

  with the more relaxed matching, there is increase of the noise level and false positives

  ঘ

  the rule of matching is based on assumptions not actual observations
• While analysing motif sequences, what is the major disadvantageous feature of PROSITE?
  ক

  The database constructs profiles to complement some of the sequence patterns

  খ

  The functional information of these patterns is primarily based on published literature

  গ

  Some of the sequence patterns are too short to be specific

  ঘ

  Lack of specificity about probability and variation and relation between them
• Emotif uses which databases for alignment of sequences?
  ক

  BLOCKS and PRINTS databases

  খ

  PROSITE

  গ

  BLOCKS

  ঘ

  PRINTS
• In regular expressions, which of the following pair of pattern is wrongly matched with its significance?
  ক

  ‘-’ – separator

  খ

  < – N-terminal

  গ

  > – C-terminal

  ঘ

  ‘>>’ – end
• In terminologies related to regular expressions which of the following is false about terms and operators?
  ক

  Terms are strings or substrings

  খ

  Operators combine terms and expressions

  গ

  Operators do not have precedence

  ঘ

  Operators have precedence like arithmetic operators
• Which of the following best defines regular expressions?
  ক

  They are made up of terms, operators and modifiers

  খ

  They describe string or set of strings to find matching patterns

  গ

  They are strictly restricted to alignment and corresponding score

  ঘ

  They consist of set of rules for the connotations of various amino acid residues
• While scanning for similarities in motifs, how regular expressions’ techniques work?
  ক

  It represents a sequence family by a string of characters and further compares them

  খ

  An algorithm similar to dynamic programming is used

  গ

  Dot matrix analysis is used in this type of sequence analysis

  ঘ

  Matrix analysis methods are used in this type