HTH Motif and Homeodomain MCQ

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• What is the DNA sequence that encodes the homeodomain known as?
  ক

  Zinc fingers

  খ

  H-T-H motifs

  গ

  Leucine zippers

  ঘ

  Homeobox
• Which of the following DNA-binding motif functions as transcriptional regulators, especially during eukaryotic development?
  ক

  Zinc fingers

  খ

  Leucine zippers

  গ

  H-T-H motif

  ঘ

  Homeodomain
• What are the genes that regulate the development of body patterns called?
  ক

  Developmental genes

  খ

  Growth genes

  গ

  Activator genes

  ঘ

  Homeotic genes
• The lac repressor has which of the following DNA-binding motifs?
  ক

  Leucine zippers

  খ

  Zinc fingers

  গ

  Homeodomain

  ঘ

  H-T-H motif
• From the H-T-H motif, only one of the two α-helical segments is called the recognition helix.
  ক

  False

  খ

  True
• The H-T-H structure is inherently very stable.
  ক

  True

  খ

  False
• What is the average length of the α-helical segments in the H-T-H motif?
  ক

  13 – 15 amino acid residues

  খ

  11 – 19 amino acid residues

  গ

  10 – 15 amino acid residues

  ঘ

  7 – 9 amino acid residues
• What is the average length of the H-T-H motif?
  ক

  30 amino acid residues

  খ

  50 amino acid residues

  গ

  100 amino acid residues

  ঘ

  20 amino acid residues
• Which DNA-binding motif has two short helical segments separated by a turn?
  ক

  H-L-H

  খ

  Leucine zipper

  গ

  Zinc fingers

  ঘ

  H-T-H
• Which among the following is not a DNA-binding motif?
  ক

  H-T-H

  খ

  Zinc fingers

  গ

  Homeodomain

  ঘ

  Homeobox
• Which of the following is a feature of a lac repressor?
  ক

  It is a dimer

  খ

  It is a trimer

  গ

  It is a monomer

  ঘ

  It is a tetramer
• Which of the following interactions majorly imparts specificity to most of the protein-DNA contacts?
  ক

  Hydrophobic interaction

  খ

  Covalent interactions

  গ

  Disulfide bonds

  ঘ

  Hydrogen bonds
• Which of the following proteins have discrete DNA-binding domains?
  ক

  Excretory proteins

  খ

  Plasma membrane proteins

  গ

  Catalytic proteins

  ঘ

  Regulatory proteins
• Considering the specificity of the protein-DNA interaction in the case of regulatory proteins it can be concluded that there is a particular amino acid-base code.
  ক

  True

  খ

  False