G-protein Receptors and Messengers MCQ

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• Epinephrine causes an increase in ____________________
  ক

  blood glucose levels

  খ

  surface receptors

  গ

  rhodopsin pigments

  ঘ

  mast cells
• The Cholera toxin produced by Vibrio cholera exerts its effect by _____________________
  ক

  modifying G-protein

  খ

  modifying primary messengers

  গ

  modifying effectors

  ঘ

  modifying receptors
• The Kaposi’s sarcoma is caused by ____________________
  ক

  Herpes virus

  খ

  Adeno virus

  গ

  Human immunodeficiency virus

  ঘ

  Retro virus
• A somatic mutation is present in all of the individual’s body cells.
  ক

  True

  খ

  False
• Adenoma is caused by the over-secretion of ____________________
  ক

  arrestin

  খ

  rhodopsin

  গ

  kinetin

  ঘ

  thyroid hormone
• Retinitis pigmentosa is an inherited disorder caused due to mutation in the gene that encodes for __________________
  ক

  G-proteins

  খ

  Arrestin

  গ

  Rhodopsin

  ঘ

  G-protein receptor kinase
• Arrestins compete with ________________ for binding with G-protein coupled receptors.
  ক

  Effectors

  খ

  Primary messengers

  গ

  Secondary messengers

  ঘ

  G-proteins
• Desensitization is the process of blocking receptors from turning on ______________
  ক

  G-proteins

  খ

  Transcription factors

  গ

  Promoters

  ঘ

  Activators
• The G-proteins bind only to _________________
  ক

  cytosine

  খ

  guanine

  গ

  thymine

  ঘ

  adenine
• The inactive conformation of a G-protein coupled receptor is stabilized by ____________________
  ক

  covalent interactions

  খ

  hydrogen binding

  গ

  non-covalent interactions

  ঘ

  ionic interactions
• Which of the following is a stimulus for rhodopsin?
  ক

  light

  খ

  acidic pH

  গ

  basic pH

  ঘ

  neurotoxins
• On the cytoplasmic site of GCPRs, the G-proteins bind to ___________________
  ক

  amino-terminus

  খ

  promoter region

  গ

  second loop

  ঘ

  third loop
• The G-protein coupled receptors have their _____________________ outside the cell.
  ক

  amino terminus

  খ

  carboxyl terminus

  গ

  alpha helices

  ঘ

  beta helices
• G-protein coupled receptors are referred to as seven-transmembrane receptors.
  ক

  True

  খ

  False