Dot Matrix Sequence Comparison MCQ

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• Dot plot of repeating elements would be small crosses on plot.
  ক

  True

  খ

  False
• Vertical frame shifts show ______ while the horizontal ones show _______
  ক

  insertion, insertion

  খ

  insertion, deletion

  গ

  deletion, deletion

  ঘ

  deletion, insertion
• Isolated dots that are not on the diagonal represent exact matches.
  ক

  True

  খ

  False
• Which of the following is true for EMBOSS Dottup?
  ক

  Allows you to specify threshold

  খ

  Doesn’t allow you to specify threshold

  গ

  Doesn’t allow you to specify window size

  ঘ

  If all cells in the window are identity, it colors in some specific cells in the window
• Who were the inventors of this method?
  ক

  Smith-Waterman

  খ

  Margaret Preston

  গ

  Gibbs and McIntyre

  ঘ

  Needleman-Wunsch
• When was this method, first described?
  ক

  1959

  খ

  1966

  গ

  1970

  ঘ

  1982
• For significantly aligning sequences what is the resulting structure on the plot?
  ক

  Intercrossing lines

  খ

  Crosses everywhere

  গ

  Vertical lines

  ঘ

  A diagonal and lines parallel to diagonal
• For palindromic sequences, what is the structure of the dot plot?
  ক

  2 intersecting diagonal lines at the midpoint

  খ

  One diagonal

  গ

  Two parallel diagonals

  ঘ

  No diagonal
• The softwares for dot plot analysis perform several tasks. Which one of them is not performed by them?
  ক

  Gap open penalty

  খ

  Gap extend penalty

  গ

  Expectation threshold

  ঘ

  Change or mutate residues