Dosage Form Factors Affecting Drug Absorption MCQ

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• Suspending agents and some sugars can be used as viscosity imparters.
  ক

  True

  খ

  False
• The concentration of colorant does not affect the drug solubility.
  ক

  True

  খ

  False
• PABA complex is used for the enhancement of ______________
  ক

  Enhanced chelation

  খ

  Enhanced dissolution

  গ

  Enhanced membrane permeability

  ঘ

  Enhanced lipophilicity
• Which one of these is not a mechanism of the working of surfactants?
  ক

  Promote wetting by increasing the effective surface area

  খ

  Helps in the dissolution of drug

  গ

  Better membrane contact of the drug

  ঘ

  Decrease membrane permeability
• Which of the following will be an example of an organic suspending agent?
  ক

  CMC

  খ

  MC

  গ

  Acacia

  ঘ

  Carbowaxes
• The deleterious effect of various coatings on drug dissolution is shown in orders below. Which one of them is the correct order?
  ক

  Enteric coat > sugar coat > nonenteric film coat

  খ

  Enteric coat > nonenteric film coat > sugar coat

  গ

  Nonenteric film coat > sugar coat > enteric coat

  ঘ

  Sugar coat > enteric coat > nonenteric film coat
• An example of lubricants will be __________
  ক

  PVP

  খ

  Carbowaxes

  গ

  CMC

  ঘ

  Tetracycline
• A large amount of binders tends to increase the hardness of tablets.
  ক

  True

  খ

  False
• Which one of the following sentences depicts the function of Disintegrants correctly?
  ক

  These agents help in holding the powders together to form granules

  খ

  These agents overcome the cohesive strength of the tablets and help in dissolution

  গ

  These agents help in the flow of granules and reduce friction between particles

  ঘ

  Added when the required dosage is inadequate
• What is the full form of PVP and what is its function in drug formation?
  ক

  Polyvinyl propylene, diluent

  খ

  Polyvinyl pyrrolidine, solubilizing agent

  গ

  Polyvinyl propylene, buffering agent

  ঘ

  Polyvinyl pyrrolidine, Binding agent
• What is the function of a granulating agent in drug formulation?
  ক

  Promote cohesive compacts

  খ

  Added if the required dosage is inadequate so that necessary bulk can be produced

  গ

  Tablets can disintegrate easily

  ঘ

  Used as solubilizer
• Which one of the following will be an example of organic diluents?
  ক

  Starch

  খ

  Dicalcium phosphate

  গ

  Tetracycline

  ঘ

  Tween 80
• Vehicles are the solvent system for the liquefied drug. Which one of them is not an example of a kind of vehicle?
  ক

  Aqueous vehicle

  খ

  Non-aqueous water-miscible vehicles

  গ

  Non-aqueous water immiscible vehicles

  ঘ

  A salt solution of the drug
• Which one of them is not a common form of excipients of drug manufacturing?
  ক

  Diluents

  খ

  Binders

  গ

  Sweeteners

  ঘ

  Essential oils
• Capsules with bigger particles and intense packing have poor drug release and dissolution rate due to an increase in the pore size.
  ক

  True

  খ

  False
• Which of these is not a characteristic of tablet formulation by Agglomerative phase of the communication process?
  ক

  Tablets are stronger

  খ

  Usage of more binding agent

  গ

  Rapid dissolution

  ঘ

  Increase in internal surface area of the granules
• The agglomerative phase of the communication method grinds the drug in a ball mill for a long time to affect spontaneous agglomeration. But results showed tablets produced are softer.
  ক

  True

  খ

  False
• Which of the following is not a limitation granulation?
  ক

  Formation of crystal bridge by the presence of liquid

  খ

  The liquid may act as a medium for affecting chemical reactions such as hydrolysis

  গ

  Increase the cost due to more additional processing

  ঘ

  The drying step may harm the thermolabile drugs
• Which of the following is not a form of excipients?
  ক

  Paracetamol

  খ

  Disintegrants

  গ

  Lubricants

  ঘ

  Binders
• Disintegration time is directly proportional to the amount of binder present in the tablet.
  ক

  True

  খ

  False
• Which tablets have longer Disintegration time?
  ক

  Single coated tablets

  খ

  Uncoated tablets

  গ

  Sugar-coated tablets

  ঘ

  Capsules
• Which form of drug formulation has disintegration time?
  ক

  Injections

  খ

  Syrups

  গ

  Capsules and Tablets

  ঘ

  Only tablets