DNA Repair MCQ

Test your knowledge with important DNA Repair MCQ and their applications. These MCQs are beneficial for competitive exams too. Explore 30+ more DNA Repair MCQs on Bissoy. Bissoy App

• Mark the one, which is CORRECT for SOS repair.
  ক

  RecA protein participates

  খ

  A free radical mechanism is involved

  গ

  The repair enzyme functions only once

  ঘ

  No bases or nucleotides are removed
• Which of the following is NOT the function of the enzyme systems involved in mismatch repair?
  ক

  Recognize mismatched base pair

  খ

  Gene conversion

  গ

  Determine incorrect base from a mismatch

  ঘ

  Excise incorrect base and carry out repair system
• Mark the one, which is NOT a subunit of ABC exinuclease?
  ক

  UvrA

  খ

  UvrB

  গ

  UvrC

  ঘ

  UvrF
• Which of the following enzyme works in the nucleotide excision repair?
  ক

  DNA photolyase

  খ

  ABC exinuclease

  গ

  DNA glycosylase

  ঘ

  RecA
• Name the enzyme which initiates base excision repair process?
  ক

  RNA polymerase

  খ

  DNA polymerase

  গ

  DNA photolyase

  ঘ

  DNA glycosylase
• Name the repair system which involves the removal of the damaged segment of DNA?
  ক

  Recombinational repair

  খ

  Direct repair

  গ

  Excision repair

  ঘ

  Mismatched repair
• Which of the following enzyme is used in photoreactivation process?
  ক

  DNA ligase

  খ

  DNA photolyase

  গ

  DNA polymerase

  ঘ

  Primase
• Name the repair system for UV mediated damage of DNA?
  ক

  Exchange of homologous segments

  খ

  DNA glycosylase

  গ

  Nucleotide excision repair

  ঘ

  Photoreactivation
• The genome can maintain its essential cellular function even without DNA repair.
  ক

  True

  খ

  False
• The correction of changes in DNA by a set of process known as___________
  ক

  Replication

  খ

  DNA repair

  গ

  Translation

  ঘ

  Transcription
• How many types of skin cancers can develop by overexposure to ultraviolet rays?
  ক

  1

  খ

  2

  গ

  3

  ঘ

  4
• Xeroderma pigmentosum is caused by ______________________
  ক

  UV radiations

  খ

  X-rays

  গ

  Gamma radiations

  ঘ

  Beta-rays
• The NHEJ pathway is used to rectify __________________ in the DNA.
  ক

  nucleotide substitutions

  খ

  double-strand breaks

  গ

  single-strand breaks

  ঘ

  mismatched basepairs
• Which of the following does not introduce double-strand breaks in the DNA?
  ক

  Gamma rays

  খ

  Cancer drugs

  গ

  Free radicals

  ঘ

  Inherited mutations
• A mismatched base pair can cause ________________ in the double helix.
  ক

  change in geometry

  খ

  change in location

  গ

  change in size

  ঘ

  change in alkalinity
• Which repair system operates to repair DNA strands that are actively transcribed?
  ক

  Double-strand breakage repair

  খ

  Nucleotide excision repair

  গ

  RNA repair

  ঘ

  Messenger RNA repair
• Which repair system operates to remove the altered bases generated by reactive chemicals present in the diet?
  ক

  Base excision repair

  খ

  Nucleotide excision repair

  গ

  Mismatch repair

  ঘ

  Double-stranded breakage repair
• How many pathways of nucleotide excision repair exist?
  ক

  1

  খ

  2

  গ

  3

  ঘ

  4
• Mutations in the DNA may be passed to the next generation.
  ক

  True

  খ

  False
• The enzyme photolyase is used in what method of repair?
  ক

  Base excision

  খ

  Photo reactivation

  গ

  Nucleotide excision

  ঘ

  None of the mentioned
• Recombinational repair is often due to ____________
  ক

  Incorporation of many incorrect nucleotides by DNA pol

  খ

  Many cystidine dimer and associated large gaps in a strand

  গ

  Many thymidine dimer formations and associated large gaps in a strand

  ঘ

  All of the mentioned
• The enzyme of E.coli is a nuclease that initiates the repair of double stranded DNA breaks by homologous recombination is?
  ক

  DNA glycosylase

  খ

  DNA ligase

  গ

  DNA polymerase

  ঘ

  RNA polymerase
• A point mutation that replaces a purine with another purine, or a pyrimidine with another pyramidine ____________
  ক

  Nonsense mutation

  খ

  Silent mutation

  গ

  Transition mutation

  ঘ

  Transversion
• An alteration in a nucleotide sequence that changes a triplet coding for an amino acid into a termination codon is ____________
  ক

  Nonsense mutation

  খ

  Mutagenesis

  গ

  Mutation

  ঘ

  Mutagen
• The DNA polymerase involved in base excision repair is ____________
  ক

  DNA polymerase α

  খ

  DNA polymerase β

  গ

  DNA polymerase σ

  ঘ

  DNA polymerase γ
• What is the function of enzyme involved in base excision repair?
  ক

  Addition of correct base

  খ

  Addition of correct nucleotide

  গ

  Removal of incorrect base

  ঘ

  Removal of phosphodiester bond
• Which of the following has the self-repairing mechanisms?
  ক

  DNA and RNA

  খ

  DNA, RNA and protein

  গ

  Only DNA

  ঘ

  DNA and proteins
• If the mutation has a negligible effect on the function of a gene, it is known as a ____________
  ক

  Silent mutation

  খ

  Frame shift mutation

  গ

  Substitution mutation

  ঘ

  Insertion mutation