Biotechnological Applications in Medicine: Gene Therapy MCQ

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• What kind of disease can be cured with the help of gene therapy?
  ক

  Infectious

  খ

  Hereditary

  গ

  Physiological

  ঘ

  Acute
• What is introduced into lymphocytes to cure ADA?
  ক

  DNA

  খ

  RNA

  গ

  ADA cDNA

  ঘ

  Lipid
• Introduction of gene isolate from bone marrow producing ADA should be introduced at what age to permanently cure ADA?
  ক

  Teenage

  খ

  Adulthood

  গ

  Old age

  ঘ

  Embryonic stage
• Lymphocytes are immortal.
  ক

  True

  খ

  False
• A functional ADA cDNA is introduced into the patient’s lymphocytes using _______ vector.
  ক

  jumping

  খ

  retroviral

  গ

  infectious

  ঘ

  bacterial
• In the first step of gene therapy, ________ from the blood of the patient are grown in a culture outside of the body.
  ক

  red blood cells

  খ

  lymphocytes

  গ

  neurons

  ঘ

  platelets
• ______ is an alternative method to cure ADA deficiency.
  ক

  Bone marrow transplantation

  খ

  Cloning

  গ

  Hybridization

  ঘ

  Sequencing
• ADA deficiency is caused due to ________ of the gene for adenosine deaminase.
  ক

  addition

  খ

  change

  গ

  deletion

  ঘ

  multiplication
• ADA stands for _______
  ক

  Adenine nucleotide amine

  খ

  Vitamin A deficiency

  গ

  Adenosine deaminase

  ঘ

  A double bond amine
• In 1990 the first gene therapy was given to treat which deficiency?
  ক

  Smallpox

  খ

  Vitamin E

  গ

  Protein

  ঘ

  Adenosine deaminase
• In which year was the first clinical gene therapy given?
  ক

  2010

  খ

  1990

  গ

  1995

  ঘ

  2000
• The inserted normal gene takes over the function of _________ gene.
  ক

  correct

  খ

  right

  গ

  non-functional

  ঘ

  functional
• In gene therapy, the genetic defect is corrected by delivery of _______ gene into the individual.
  ক

  incorrect

  খ

  mutant

  গ

  normal

  ঘ

  jumping
• In gene therapy, the gene defects are cured in a child or ________ stage.
  ক

  adult

  খ

  teenage

  গ

  old

  ঘ

  embryo
• A collection of methods that allows correction of a gene that has been diagnosed in child/embryo is called _________
  ক

  cloning

  খ

  gene therapy

  গ

  chemotherapy

  ঘ

  dialysis
• A person with the hereditary disease can be cured with the help of _________
  ক

  gene therapy

  খ

  cloning

  গ

  dialysis

  ঘ

  chemotherapy