Zoldem

Zoldem Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Zoldem is a brand name. Its generic name is Zolpidem.

Introduction of Zoldem

Zoldem is a sedative-hypnotic medication that is used to help people sleep. It is commonly known under the brand name Ambien, and it works by shortening the time it takes to fall asleep, and helping people stay asleep for longer periods of time. Zoldem belongs to a group of drugs called the non-benzodiazepines, which have similar effects to the benzodiazepines, such as Valium and Xanax.

Uses for Zoldem

Zoldem is mainly used in the short-term treatment of insomnia. It can also be used for the relief of symptoms of sudden withdrawal of alcohol and other sedatives, and for the treatment of panic attacks and other anxiety disorders. Zoldem can also be prescribed for chronic pain, headaches and other sleep disorders.

Mechanism of Action

Zoldem works by increasing the activity of the neurotransmitter GABA in the brain. It binds to the GABA receptors, which produces a calming effect in the brain. The exact mechanism through which it works is still unknown, but it is believed that the drug helps to stimulate specific neurons that are involved in achieving a state of relaxation.

How Long Does It Take to Work?

The effects of Zoldem can usually be felt within 10–15 minutes after taking it, and usually lasts for up to 8 hours. It is recommended to take the drug about 1–2 hours before bedtime, as this will give the drug time to be absorbed into the bloodstream and begin its effects.

Absorption

Zoldem is absorbed quickly from the gastrointestinal tract, at a rate of approximately 90 percent. It has a bioavailability of 70-86 percent and a terminal elimination half-life of around 3–5 hours.

Route of Elimination

Zoldem is eliminated mainly by metabolism, and only about 10 percent is eliminated unchanged in the urine. It is mostly eliminated through the kidneys via the renal system.

Dosage

Zoldem comes in several different forms of oral tablets, such as immediate release (Ambien, Ambien CR), extended release (Edluar, Intermezzo), and sublingual tablets (Zolpimist). Each form has a different dosage and should only be taken as directed by a doctor.

Immediate Release:

• Adults—5 or 10 mg once a day, just before going to bed
• Elderly—5 mg once a day
• People with liver disease—5 mg once a day

Extended Release:

• Adults—6.25 mg once a day, just before going to bed
• Elderly—6.25 mg once a day
• People with liver disease—6.25 mg once a day

Sublingual Tablets:

• Adults—5 mg once a day, just before bedtime
• Elderly—5 mg once a day
• People with liver disease—5 mg every other day

Administration

The usual method of administration for Zoldem is by oral tablet. It is recommended to take the drug just before bedtime, as this will help to maximize its effects. It is important to read the directions before taking the medication, as some forms may need to be taken on an empty stomach.

Side Effects

Common side effects of Zoldem can include drowsiness, dizziness, headache, nausea, vomiting, dry mouth, fatigue, lightheadedness, and diarrhea. Serious side effects can include breathing difficulties, memory loss, confusion, depression, and suicidal thoughts.

Toxicity

The lethal dose of Zoldem is not known; however, an overdose of the drug can be dangerous and even deadly. Symptoms of an overdose can include confusion, shortness of breath, depressed breathing, coma, and death.

Precautions

Zoldem should not be taken if you have any of the following conditions: severe liver or kidney disease, sleep apnea, severe depression, alcohol or other drug abuse, or if you are pregnant or nursing.

Interactions

Zoldem can interact with certain medications, such as antidepressants, antifungals, or seizure medications. It can also interact with alcohol, so it is important to avoid consuming alcohol while taking the medication. It is important to tell your doctor about any medications you are taking before taking Zoldem.

Disease Interactions

Zoldem can worsen certain medical conditions, such as dementia, glaucoma, asthma, and depression. It can also make certain medical conditions worse, such as sleep apnea, high blood pressure, and seizure disorders.

Drug Interactions

Zoldem can interact with certain medications, such as antidepressants, antifungals, or seizure medications. It is important to tell your doctor about any medications you are taking before taking Zoldem.

Food Interactions

Zoldem can interact with certain foods, such as dairy products, grapefruit, and alcohol. It is important to tell your doctor about any foods you are consuming when taking Zoldem.

Pregnancy Use

Zoldem is not recommended for use during pregnancy due to the potential risks it poses to the unborn child. If you are pregnant or planning to become pregnant, it is important to discuss the risks with your doctor before taking the medication.

Lactation Use

Zoldem is not recommended for use during lactation due to the potential risks it poses to the infant. If you are breast-feeding or planning to breast-feed, it is important to discuss the risks with your doctor before taking the medication.

Acute Overdose

Symptoms of an overdose of Zoldem can include confusion, shortness of breath, depressed breathing, coma, and death. If an overdose is suspected, it is important to seek medical attention immediately.

Contraindication

Zoldem is contraindicated in patients with severe liver or kidney disease, sleep apnea, severe depression, alcohol or other drug abuse, or if you are pregnant or nursing.

Use Direction

Zoldem should only be taken as directed by a doctor. It is recommended to take the drug just before bedtime, as this will help to maximize its effects. It is important to read the directions before taking the medication, as some forms may need to be taken on an empty stomach.

Storage Condition

Zoldem should be stored in a cool, dry place, away from direct light and moisture. It should also be kept out of the reach of children and pets. The tablets should not be crushed or chewed, as this may result in over-dosage.

Volume of Distribution

The volume of distribution of Zoldem is 0.63 L/kg, meaning that it is distributed evenly throughout the body. This means that the drug can be taken orally and is absorbed quickly into the bloodstream and distributed to the tissues and organs of the body.

Half Life

The elimination half-life of Zoldem is around 3–5 hours, meaning it will take about five hours for half of the drug to be eliminated from the body. This indicates that it will take about 15–25 hours for the drug to be completely eliminated from the body.

Clearance

The clearance of Zoldem is about 6.6 L/h, meaning that it is removed from the body at a rate of 6.6 liters per hour. This indicates that it takes about six hours for the drug to be eliminated from the body.

Here you find in details version of Zoldem

Some Frequently Asked Questions About Zoldem

What is Zoldem?

Zoldem is a prescription sedative-hypnotic medication used to treat insomnia. It is available under the brand name Ambien or its generic name Zoldem.

What are the common side effects of Zoldem?

The most common side effects of Zoldem are drowsiness, dizziness,lightheadedness, clumsiness, unsteadiness, and headache.

How long does Zoldem stay in your system?

Zoldem has a half-life of approximately two to three hours, so it typically leaves your system in six to 8 hours after taking a single dose.

What are the different strengths of Zoldem?

Zoldem is available in two different strengths: 5 mg and 10 mg. Your doctor will determine which strength is best for you depending on your particular health condition and response to the medication.

What is the difference between Zoldem and Ambien?

Zoldem is the generic name for the prescription medication Ambien. Both medications contain the same active ingredient, zolpidem, and are used to treat insomnia.

What is the maximum daily dose of Zoldem?

The maximum recommended daily dose of Zoldem is 10 mg. If your doctor prescribes a higher dose, you should take only the amount prescribed and not exceed the maximum amount.

Is Zoldem habit-forming?

Yes, Zoldem can be habit-forming if taken in larger doses than recommended or for longer than prescribed. It is important to take the medication only as prescribed by your doctor.

Can Zoldem be taken with other medications?

Zoldem may interact with other medications. It is important to tell your doctor about any other medications you are taking before starting Zoldem.

What are the potential risks associated with Zoldem?

The most common potential risks associated with Zoldem include dizziness, confusion, memory problems, unsteadiness, and day-time drowsiness. Long-term use can also lead to dependence on the medication and withdrawal symptoms if stopped suddenly.

Can Zoldem be used long-term?

Long-term use of Zoldem is not recommended. Zoldem should be used for the shortest amount of time possible and only when necessary. Your doctor may adjust your dose or frequency of use to help minimize any potential risks associated with long-term use.

Can Zoldem be used on an as-needed basis?

Yes, Zoldem can be used on an as-needed basis. However, you should take the entire prescribed dose as recommended by your doctor. Do not take more or less than the prescribed amount.

Can Zoldem be used for sleepwalking and sleep eating?

Yes, Zoldem can be used to treat sleepwalking and sleep eating. In some cases, it may be prescribed alongside other medications to treat these conditions.

Is Zoldem effective for treating insomnia?

Yes, Zoldem is effective for treating insomnia. It works by slowing down brain activity and allowing the user to fall asleep more quickly and stay asleep longer.

Can Zoldem be taken with alcohol?

No, Zoldem should not be taken with alcohol. Alcohol and Zoldem both have a sedative effect on the body, which can lead to excessive sedation and an increased risk of serious side effects.

Can Zoldem cause memory problems?

Yes, Zoldem can cause memory problems. Common side effects include confusion, forgetfulness, and difficulty recalling information. Be sure to talk to your doctor about any memory problems that may occur.

Should Zoldem be taken during pregnancy?

No, Zoldem should not be taken during pregnancy. There is not enough evidence to suggest that it is safe to use during pregnancy, so it is best to avoid taking it.

Can Zoldem be taken by people with liver or kidney problems?

Yes, Zoldem can be taken by people with kidney or liver problems, however the dose may need to be adjusted. Your doctor will determine the best dosage for you based on your health condition.

Does Zoldem cause weight gain or loss?

No, Zoldem does not typically cause weight gain or loss. It is possible that you may experience appetite changes while taking this medication, but this is not a common side effect.

Can Zoldem be taken with antidepressants?

Yes, Zoldem can be taken with antidepressants. However, it is important to talk to your doctor before taking any medications together as there may be drug interactions. Your doctor will determine the best dosage and treatment plan for you.

Is Zoldem safe for elderly people?

Yes, Zoldem is safe for elderly people, however the dose may need to be adjusted. Your doctor will determine the best dosage for you based on your health condition.

Are there any over-the-counter sleep aids similar to Zoldem?

No, there are no over-the-counter sleep aids that are similar to Zoldem. Zoldem is a prescription medication and should only be taken as directed by your doctor.

Does Zoldem cause a hangover?

No, Zoldem does not typically cause a hangover. However, it is possible to experience some memory and concentration problems the day after taking Zoldem. If this occurs, talk to your doctor.

Can children take Zoldem?

No, Zoldem should not be used by children. It is not recommended for use in children under 18 years of age.

Does Zoldem interact with other medications?

Yes, Zoldem can interact with other medications. It is important to tell your doctor about any other medications you are taking before starting Zoldem. This will allow your doctor to adjust the dosage and frequency of the medication if necessary.

Will I become addicted to Zoldem?

It is possible to become addicted to Zoldem if taken in larger doses than recommended or for longer than prescribed. It is important to take the medication only as prescribed by your doctor.

Can Zoldem be used to treat anxiety?

No, Zoldem is not typically used to treat anxiety. It is used as a sleep aid, so if you are having difficulty sleeping due to anxiety, talk to your doctor about other treatments that may be appropriate.

At what age can Zoldem be used?

Zoldem is not recommended for use in children under 18 years of age. Some manufacturers may include specific guidelines for use in adolescents. Talk to your doctor to see if Zoldem is the right option for you.

What are the long-term effects of Zoldem?

Long-term use of Zoldem can lead to physical and psychological dependence. This can result in withdrawal symptoms if the medication is stopped suddenly. It can also make it more difficult to stop taking the medication. Talk to your doctor about any concerns you have about long-term use of Zoldem.

Does Zoldem cause rebound insomnia?

Yes, rebound insomnia is a potential side effect of taking Zoldem. It is a condition in which the user experiences an increase in insomnia symptoms when they stop taking the medication.

Can Zoldem cause sleep apnea?

No, Zoldem does not typically cause sleep apnea. However, it is possible that sleep apnea can become worse in some individuals who are taking Zoldem. Talk to your doctor if you experience any new or worsening symptoms.

Can you develop a tolerance to Zoldem?

Yes, it is possible for users to develop a tolerance to Zoldem. This means that the user will need higher doses of the medication to achieve the same effects. If you notice a lack of effectiveness in the medication, talk to your doctor.

Can Zoldem be used to treat depression?

No, Zoldem is not typically used to treat depression. It may be used to help with sleeping problems caused by depression, but it is not a replacement for antidepressants. Talk to your doctor about your symptoms and which medications may be best for you.

Can Zoldem be used to treat insomnia caused by jet lag?

Yes, Zoldem can be used to treat insomnia caused by jet lag. It should only be taken as needed and the recommended dose should not be exceeded.

Can Zoldem be taken with ibuprofen?

Yes, Zoldem can be taken with ibuprofen. However, it is important to talk to your doctor before taking any medications together as there may be drug interactions. Your doctor will determine the best dosage and treatment plan for you.

Can Zoldem cause confusion?

Yes, Zoldem can cause confusion. Other common side effects include dizziness, forgetfulness, clumsiness, unsteadiness, and headache.

Is Zoldem habit-forming?

Yes, Zoldem can be habit-forming if taken in larger doses than recommended or for longer than prescribed. It is important to take the medication only as prescribed by your doctor.

Can Zoldem cause nightmares?

Yes, Zoldem can cause nightmares. In some cases, it can also cause feelings of anxiety, depression, or irritability. If you experience any of these symptoms, talk to your doctor.

Can Zoldem be used to treat chronic insomnia?

Yes, Zoldem can be used to treat chronic insomnia. It is important to talk to your doctor before starting any treatment for chronic insomnia as there may be other factors involved.

Can Zoldem be used to treat night terrors?

No, Zoldem is not typically used to treat night terrors. It may be used as a short-term sleep aid, but it is not recommended for long-term use for this condition.

Can Zoldem be used to treat insomnia caused by anxiety?

Yes, Zoldem can be used to treat insomnia caused by anxiety. It is important to talk to your doctor about your symptoms and which medications may be best for you.

Does Zoldem have any interactions with other drugs?

Yes, Zoldem can interact with other medications. It is important to tell your doctor about any other medications you are taking before starting Zoldem. This will allow your doctor to adjust the dosage and frequency of the medication if necessary.