Xenical

Xenical Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Xenical is a brand name. Its generic name is Orlistat.

Xenical Introduction

Xenical is a medicine used for weight management. It belongs to a group of medicines known as gastrointestinal lipase inhibitors, or GI lipase inhibitors, and it works by reduing the amount of fat that is absorbed by the body. Xenical is available both over-the-counter (OTC) and in prescription form, and is marketed under various brand names, such as Xendos and Alli.

Uses for Xenical

Xenical is used to help enhance weight loss in overweight adults who are taking part in a weight-loss program. It is also used in certain patients for obesity management. Xenical may be used in conjunction with other medications and a reduced-calorie diet to achieve greater weight-loss.

Mechanism Of Action

Xenical works by inhibiting the absorption of fat in your body. It does this by inhibiting an enzyme in the stomach and intestines called lipase. The lipase enzyme helps the body break down and absorb fat. When Xenical blocks the action of the lipase enzyme, less fat is absorbed from the diet, resulting in a smaller increase in blood fat levels.

In addition to its weight loss benefits, Xenical can also reduce triglyceride levels and improve blood cholesterol levels. This is important because both elevations in triglyceride levels and blood cholesterol levels are associated with an increased risk of cardiovascular disease.

How Long Does It Take To Work?

The effectiveness of Xenical depends on its adequate and consistent use. Most people will begin to see results within three months of regularly taking the dosage of Xenical prescribed by their doctor. However, it is important to follow the recommended instructions to maximize the effects of the medication.

Absorption

Xenical is mostly not absorbed in the body, it mainly works in the lower intestine and only a small amount is absorbed into the bloodstream. The medication is broken down by the gut bacteria in the lower intestine.

Route Of Elimination

The inactive metabolites are eliminated as feces, and the active form of the drug is eliminated in urine.

Dosage

The recommended dose of Xenical is one 120 mg capsule, taken orally with a full glass of liquid, three times a day. Xenical is generally taken during, or up to one hour after each main meal of the day. The missed doses should be skipped and the regular schedule should be resumed.

Administration

Xenical can be taken orally with a full glass of liquid either before, during or up to one hour after each meal. It should not be taken more than three times a day.

Side Effect

The most common side effects associated with Xenical include gas with discharge, loose stools, abdominal pain, fecal urgency, difficulty controlling bowel movements, increased bowel movements, diarrhea, nausea, and headache.

Toxicity

Xenical is relatively nontoxic and the most severe side effect can be gastrointestinal (GI) distress. If Xenical is taken with meals that are very high in fat, the side effects may be more pronounced. In such cases, Xenical should be discontinued until the symptoms resolve.

Precaution

Before taking Xenical, you should tell your doctor if you have ever had any type of liver or kidney problems. You should also tell your doctor if you have gallbladder problems or if you are pregnant or plan to become pregnant.

Interaction

Xenical should not be taken with certain medications such as warfarin, because it can reduce the effectiveness of the warfarin and increase the risk of bleeding. Xenical should also not be taken with some vitamins, as their absorption may be reduced.

Disease Interaction

Xenical may interact with certain disease states and alter their natural history. For example, Xenical has been linked to reduced risk of Crohn's disease, colorectal cancer, and type 2 diabetes. It is important to discuss any potential interactions with your doctor before taking Xenical.

Drug Interaction

Certain drugs may interact with Xenical. For example, if you take anticoagulants, such as warfarin, the effectiveness of the drug may be reduced by Xenical. In addition, some medications, such as thyroid hormones, can interact with Xenical.

Food Interactions

Xenical should be taken with meals that contain less than 30% fat in order for it to be most effective. Foods such as nuts, seeds, fried foods, creamy sauces, gravies, and high-fat dairy products should be avoided, as these foods tend to be high in fat.

Pregnancy Use

Xenical is not recommended for women who are pregnant, breastfeeding, or trying to become pregnant as it may interfere with the absorption of important nutrients. Women should also not take Xenical if they are nursing, as it may interfere with the production of breast milk.

Lactation Use

It is not recommended for breastfeeding women to take Xenical, as it may interfere with the production of breast milk.

Acute Overdose

In the event of an overdose, the patient should stop taking the medication and seek immediate medical attention. Signs and symptoms of an overdose may include abdominal cramps, nausea, and diarrhea.

Contraindication

Xenical is contraindicated in patients with chronic malabsorption syndromes, as well as those with known hypersensitivity to Xenical or any of its components.

Use Directions

Xenical should be taken as directed by your physician. Generally, the recommended dose is one 120mg capsule taken with a full glass of liquid up to three times a day with meals. Xenical should not be taken with meals that contain more than 30% fat. It is important to follow the instructions provided by your physician in order to maximize the effectiveness of the medication.

Storage Conditions

Xenical should be stored at room temperature away from moisture and light. It should be kept out of the reach of children and pets.

Volume Of Distribution

Xenical has a volume of distribution of 11.7 L and is not significantly bound to plasma proteins.

Half Life

The half life of Xenical is approximately 1 to 2 hours.

Clearance

The clearance of Xenical is approximately 20 L/h.

Here you find in details version of Xenical

Some Frequently Asked Questions About Xenical

What is Xenical?

Xenical is a prescription weight loss medication which is used to aid in weight loss, or to help reduce the risk of regaining weight already lost.

What does Xenical do?

Xenical works by blocking some of the fat that you consume from being absorbed by your body. This helps you to reduce the amount of fat absorbed from your diet, helping you to lose weight and reduce the risk of regaining weight.

How long does Xenical take to start working?

Xenical should begin to take effect within a few days of starting treatment. However, the effects of Xenical will be most noticeable after you have been using it for a few weeks.

What is a typical dose of Xenical?

The recommended dose of Xenical is one capsule three times a day, taken during or up to one hour after each main meal. Do not take more than the recommended dose.

How long can I take Xenical for?

Xenical should only be taken for a maximum of six months. After six months, it is recommended that you have a break of one month before starting the treatment again. That said, if you are still losing weight after six months, consider changing to a different form of weight loss treatment.

Can I buy Xenical over the counter?

No, Xenical is only available with a valid prescription from your doctor or another healthcare professional.

Does Xenical have any side effects?

Like all medications, Xenical can cause side effects. Common side effects of Xenical include changes in bowel habits, oily spotting, passing gas, and an increased number of bowel movements. Speak to your doctor if you experience any side effects while taking Xenical.

Is Xenical suitable for everyone?

No, Xenical is not suitable for everyone. If you have any underlying health condition, such as liver or kidney disease, Xenical is not suitable for you. Speak to your doctor or pharmacist before taking Xenical.

Does Xenical interact with other medications?

Yes, Xenical may interact with other medications. Therefore, it is important to tell your doctor or pharmacist about all medications you are taking, before starting Xenical, to ensure that all interactions are avoided.

Does Xenical cause weight loss without dieting?

No, Xenical does not cause weight loss without dieting. Xenical is used to aid weight loss, or to help reduce the risk of regaining weight already lost. It is important to stick to a reduced calorie, low-fat diet whilst taking Xenical in order to achieve the best results.

Is Xenical suitable for people with diabetes?

Yes, Xenical may be suitable for people with diabetes. However, it is important to discuss this with your doctor, in case any additional dietary advice is needed. Additionally, if you are taking any diabetes medications, it is important to tell your doctor before starting Xenical.

What should I do if I forget to take Xenical?

If you forget to take a dose of Xenical, simply take it as soon as you remember. Do not take a double dose to make up for the dose that you have missed.

Does Xenical have any long-term effects?

No, Xenical does not have any long-term effects. Once you stop taking Xenical, any unwanted effects should stop within a few days.

Does Xenical interact with any herbal remedies?

Yes, you should not take any herbal remedies whilst taking Xenical, as they may interact and cause unwanted side effects. Always tell your doctor or pharmacist about any herbal remedies you are taking before starting Xenical.

Does Xenical cause weight gain?

No, Xenical does not cause weight gain. In fact, it is used to aid weight loss or to help reduce the risk of regaining weight already lost.

Is Xenical suitable for children?

No, Xenical is not suitable for children. Xenical is a weight loss medication for adults over the age of 18 only.

Does Xenical work without exercise?

No, Xenical should only be taken in conjunction with a calorie-controlled diet and regular exercise. Taking Xenical without dieting or exercise is unlikely to be effective.

Is Xenical safe to use while breastfeeding?

It is not recommended to take Xenical when breastfeeding. Speak to your doctor for further advice on how to safely lose weight while breastfeeding.

Is Xenical available on the NHS?

Yes, Xenical is available on the NHS for people with a BMI over 30, and those with a BMI over 28 who have other health risks associated with being overweight or obese.

Is Xenical safe to take while pregnant?

No, Xenical is not safe to take while pregnant. Speak to your doctor or midwife for advice on safe weight loss while pregnant.

Does Xenical cause constipation?

Xenical may cause changes to your bowel habits. If you experience constipation while taking Xenical, speak to your doctor or pharmacist for advice on how to prevent or relieve it.

How quickly will I lose weight when taking Xenical?

Weight loss with Xenical will vary from person to person. However, you should aim to lose at least 5% of your starting weight during the first three months of treatment.

What foods should I avoid while taking Xenical?

It is important to stick to a reduced-calorie, low-fat diet while taking Xenical. Foods that are high in saturated fat, such as full-fat dairy products, processed foods, and fried foods should be avoided.

Is Xenical related to fat burning?

No, Xenical is not related to fat burning. Xenical works by blocking some of the fat that you consume from being absorbed by your body. This helps you to reduce the amount of fat absorbed from your diet, helping you to lose weight and reduce the risk of regaining weight.

How often should I take Xenical?

The recommended dose of Xenical is one capsule three times a day, taken during or up to one hour after each main meal. Do not take more than the recommended dose.

How should Xenical be stored?

Xenical should be stored at room temperature, away from moisture and heat. Ensure the capsule is tightly closed when not in use. Keep all medications out of the reach of children.

Can Xenical be used for weight loss in people with type 2 diabetes?

Yes, Xenical may be used to aid weight loss in people with type 2 diabetes. However, it is important to speak to your doctor first, as any additional dietary advice may be needed.

Does Xenical cause fatigue?

Fatigue is not a common side effect of Xenical. If you experience any unwanted side effects while taking Xenical, such as fatigue, speak to your doctor or pharmacist for advice.

Is Xenical suitable for vegetarians?

Yes, Xenical is suitable for vegetarians as the capsules are made from ingredients derived from plant sources.

Does Xenical cause nausea?

Nausea is not a common side effect of Xenical. However, speak to your doctor or pharmacist if you experience any unwanted side effects while taking Xenical.

Is diet and exercise essential for taking Xenical?

Yes, a calorie-controlled diet and regular exercise are essential for achieving the best results when taking Xenical. Try to exercise at least five times a week, for at least 30 minutes per day. Additionally, it is important to stick to a healthy, balanced diet to ensure your body is getting the nutrients that it needs.

What is the best way to take Xenical?

The best way to take Xenical is to take the capsule during or up to one hour after each main meal. Do not take more than the recommended dose and stick to a calorie-controlled diet and regular exercise for best results.

Can Xenical be taken long-term?

No, Xenical should not be taken long-term. Xenical should only be taken for a maximum of six months. After six months, it is recommended that you have a break of one month before starting the treatment again. That said, if you are still losing weight after six months, consider changing to a different form of weight loss treatment.

Is Xenical safe to take for a long period of time?

No, Xenical should not be taken for a long period of time. Xenical should only be taken for a maximum of six months. After six months, it is recommended that you have a break of one month before starting the treatment again. That said, if you are still losing weight after six months, consider changing to a different form of weight loss treatment.

How long after taking Xenical can I drink alcohol?

Alcohol should be avoided while taking Xenical. Alcohol may further reduce the absorption of fat from the body, leading to fluctuations in blood sugar levels. It is recommended to avoid alcohol until after you have finished your course of Xenical.

How quickly will I notice results when taking Xenical?

Weight loss with Xenical will vary from person to person. However, you should aim to lose at least 5% of your starting weight during the first three months of treatment. Results should begin to be noticeable within a few days of starting Xenical, but the effects will be more noticeable after you have been using it for a few weeks.

Can I take Xenical if I am taking other medications?

Yes, it is possible to take Xenical if you are taking other medications. However, it is important to tell your doctor or pharmacist about any other medications you are taking, before starting Xenical, to ensure that all interactions are avoided.

Can I take Xenical while on other forms of weight loss treatments, such as weight watchers?

Yes, you can take Xenical while on other forms of weight loss treatments, such as weight watchers. However, speak to your doctor or pharmacist if you are considering combining Xenical with any other weight loss treatments, as drug interactions may occur.

Does Xenical cause any permanent changes to my body?

No, Xenical does not cause any permanent changes to your body. Any unwanted effects should stop within a few days of stopping treatment.

Can Xenical be used to treat obesity?

Yes, Xenical can be used to aid weight loss for people with obesity. However, it is important to stick to a reduced-calorie, low-fat diet and regular exercise for best results.