Romilast

Romilast Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Romilast is a brand name. Its generic name is Montelukast.

Introduction

Romilast is a leukotriene receptor antagonist medication prescribed to prevent and control asthma symptoms. Romilast is also used to treat hay fever and allergies. Romilast works by blocking the action of leukotrienes, which are substances that may contribute to the symptoms of asthma.

Uses for

Romilast is used to manage or prevent asthma symptoms in adults and children as young as 12 months old. It may also be prescribed to relieve the symptoms of seasonal hay fever.

Mechanism of Action

Romilast works by inhibiting the action of leukotrienes, lipids released from certain cells that can cause asthma-like symptoms such as wheezing, coughing, and mucus production. By blocking the effects of these chemicals, Romilast helps reduce or prevent asthma symptoms.

How long does it take to work?

Romilast usually begins to work within one hour of administration, and most people begin to notice improvement within a day. However, it is important to remember that Romilast alone can't replace preventive care and should be used as directed by your healthcare provider.

Absorption

Romilast is rapidly and completely absorbed from the gastrointestinal (GI) tract and is not significantly affected by food. Peak plasma concentration of Romilast is generally reached within 2 hours of oral administration.

Route of Elimination

Romilast is eliminated mainly via the kidneys and biliary system. Less than 6.5% of the drug is eliminated unchanged in urine; the remaining eliminated compound is composed of metabolites undergoing glucuroconjugation or cationic exchange.

Dosage

The usual recommended daily dosage of Romilast for adults and adolescents 15 years and above is one 10 mg tablet. For children 6 to 14 years of age, the recommended daily dosage is 5 mg. For children younger than 6 years of age, the recommended daily dosage is 4 mg.

Administration

Romilast tablets should be taken with water, and should not be crushed, chewed, or broken. The tablets should be taken in the evening, as Romilast is best absorbed at night.

Side Effect

The most common side effects of Romilast may include headache, nausea, stomach-ache, throat pain, sinus pain, cough, and diarrhea. If you experience any of these side effects, contact your healthcare provider immediately.

Toxicity

Romilast is generally well tolerated in most patients, although there have been reported cases of muscle breakdown and hepatic dysfunction in patients taking very large doses, or in combination with other medications.

Precaution

Before taking Romilast, it is important to tell your healthcare provider about any other medications you are taking (including over-the-counter drugs and supplements). Romilast should not be taken if you are taking an oral steroid medication.

Interactions

Romilast can interact with some other medications, herbal products, and dietary supplements. Before taking Romilast, it is important to tell your healthcare provider about any other medications you are taking.

Disease Interactions

Taking Romilast may cause an increased risk of bleeding in some people with certain diseases, such as bleeding disorders, high blood pressure, or a blood clotting disorder. People with a history of heart attack, stroke, or liver problems should also talk to their healthcare provider before taking Romilast.

Drug Interactions

Romilast has known interactions with non-steroidal anti-inflammatory drugs (NSAIDs), antiviral drugs, and warfarin. Taking Romilast with other drugs may cause adverse interactions or unwanted side effects. Talk to your healthcare provider before taking any medications while on Romilast.

Food Interactions

Romilast can be taken with or without food. It is not significantly affected by food, however, food can cause indigestion so it is best to take Romilast with food to reduce stomach upset.

Pregnancy Use

Romilast has not been adequately studied in pregnant women. However, it is generally considered safe for pregnant women in the treatment of asthma when the benefits of the medication outweigh the risks. Speak to your healthcare provider for more information.

Lactation use

Romilast passes into breast milk in small amounts. Although studies have not been performed, it is not likely to harm a breastfed infant. Talk to your healthcare provider about the risks and benefits of using Romilast while breastfeeding.

Acute Overdose

Symptoms of a Romilast overdose may include dizziness, drowsiness, confusion, nausea, vomiting, and abdominal pain. Contact your healthcare provider immediately if you experience any of these symptoms or suspect an overdose.

Contraindications

Do not take Romilast if you are taking an oral steroid medication, if you have a known allergy to Romilast or any of its inactive ingredients, or if you are pregnant or breastfeeding.

Use Direction

Take Romilast exactly as prescribed by your healthcare provider. Follow all directions on the prescription label. Do not take more or less than prescribed. Do not stop taking Romilast without talking to your healthcare provider first.

Storage Condition

Store Romilast tablets at room temperature away from moisture and heat. Do not store in the bathroom. Keep all medications out of the reach of children and pets.

Volume of Distribution

The volume of distribution of Romilast is approximately 0.4 L/kg.

Half-Life

The mean elimination half-life of Romilast is approximately 3-6 hours.

Clearance

The total body clearance of Romilast is approximately 0.35 mL/min/kg.

Here you find in details version of Romilast

Some Frequently Asked Questions About Romilast

What is Romilast?

Romilast is a prescription medication used to prevent asthma attacks and relieve symptoms of season allergies, including sneezing, runny nose, and itchy or watery eyes. It belongs to a class of drugs known as leukotriene receptor antagonists.

How does Romilast work?

Romilast works by blocking the production of substances in the body that are responsible for allergic reactions. By blocking these substances, Romilast prevents the onset of allergic responses such as sneezing, runny nose, and itchy eyes.

Is Romilast safe?

Romilast is generally regarded as a safe drug. However, as with any medication, it is important to discuss potential side effects with your healthcare provider before starting treatment.

Is Romilast used for children?

Yes, Romilast is approved by the FDA for use in children as young as 2 years old. It is important to work with your doctor to determine the most appropriate dosage for your child.

What are the side effects of Romilast?

Common side effects of Romilast include sore throat, headache, stomach pain, diarrhea, and itching. Other side effects may include dizziness, difficulty sleeping, and rash.

What is the maximum dosage for Romilast?

The maximum dose of Romilast for adults is one 10mg tablet per day. The maximum dose for children is 5mg per day.

Can I take Romilast with other medications?

It is important to discuss taking Romilast with other medications with your healthcare provider. Some medications may interact with Romilast and should not be taken together.

Can I take Romilast while pregnant?

Romilast is not recommended for use during pregnancy. If you are planning to become pregnant, speak with your doctor about alternatives to Romilast.

How quickly does Romilast start working?

Romilast usually begins to work within 1 hour of taking the medication. However, full effects may take up to 8 hours.

What is the generic name for Romilast?

The generic name for Romilast is leukotriene receptor antagonist.

How does Romilast help with asthma?

Romilast helps to prevent asthma attacks by blocking the production of substances in the body that cause asthma flare-ups. This can reduce the severity of symptoms, allowing sufferers to breathe easier and more freely.

Can I take Romilast when breastfeeding?

It is not advised to take Romilast while breastfeeding due to the risk of passing the drug through breastmilk. Speak with your healthcare provider about possible alternatives.

Is Romilast the same as Singulair?

Yes, Romilast is the generic name for the brand name drug Singulair.

Can Romilast be purchased over the counter?

No, Romilast is a prescription medication and must be prescribed by a healthcare provider.

What is Romilast used to treat?

Romilast is used to prevent asthma attacks and relieve symptoms of season allergies, including sneezing, runny nose, and itchy or watery eyes.

Can I take Romilast with antihistamines?

It is important to speak with your doctor before taking Romilast with other medications. Some medications, including histamines, may interact with Romilast.

How is Romilast taken?

Romilast is taken orally and is usually taken once a day with or without food. It should be taken at the same time each day.

What are the possible complications of taking Romilast?

Romilast can cause serious side effects, including anaphylaxis (a severe allergic reaction) and an increased risk of certain infections. It is important to discuss the potential complications of taking Romilast with your healthcare provider.

Does Romilast expire?

Yes, Romilast can expire. It is important to check the expiration date on the medication and store according to package instructions.

Does Romilast weaken the immune system?

There is no evidence that Romilast weakens the immune system. However, it may reduce the severity of allergic reactions, which can reduce the risk of infections.

How soon after taking Romilast will I see improvement?

It typically takes 1-8 hours for Romilast to start working. Improvement in symptoms may be felt within a few days to a week of starting treatment.

What is the recommended dosage for Romilast?

The recommended dosage of Romilast is one 10mg tablet per day for adults and 5mg per day for children ages 2 to 5 years old. Your healthcare provider can advise on the most appropriate dosage for you or your child.

Can I take Romilast if I have liver or kidney problems?

Romilast is not recommended for use in patients with liver or kidney disease. It is important to discuss other treatment options with your healthcare provider.

Does Romilast cause weight gain?

Weight gain is a rare side effect of Romilast. If you experience an increase in appetite while taking Romilast, speak with your doctor.

Can Romilast cause dizziness?

Yes, dizziness is a common side effect of Romilast. If you experience dizziness while taking Romilast, discuss this with your healthcare provider.

Does Romilast have any risks associated with long-term use?

In general, Romilast is safe for long-term use. However, long-term use may increase the risk of certain side effects, including liver toxicity and headaches. Discuss the risks with your healthcare provider.

Does Romilast have any effect on blood pressure?

Romilast is not known to affect blood pressure. However, if you experience a sudden increase in blood pressure while taking Romilast, contact your doctor right away.

Can I take Romilast and ibuprofen together?

It is important to discuss taking Romilast with other medications with your healthcare provider. Some medications may interact with Romilast and should not be taken together.

Can Romilast be used for COPD?

Romilast is not approved by the FDA for use in patients with COPD. Speak with your doctor to determine the most appropriate treatment for you.

Does Romilast improve breathing?

Romilast can help to reduce the severity of asthma symptoms and improve breathing. However, it is important to follow your healthcare provider's instructions for proper use.

What is the allergy medicine Romilast called?

The allergy medicine Romilast is also known by the brand name Singulair. It is a prescription medication used to prevent asthma attacks and relieve symptoms of season allergies, including sneezing, runny nose, and itchy or watery eyes.

Can I take Romilast while drinking alcohol?

It is not advised to mix alcohol and Romilast, as this may increase the risk of side effects. Speak with your doctor if you have concerns about mixing alcohol and Romilast.

What is the difference between Romilast and Advair?

Romilast is a prescription medication used to prevent asthma attacks and relieve symptoms of season allergies. Advair is a prescription medication used for the prevention and treatment of airway narrowing caused by asthma, chronic bronchitis, and emphysema.

Can Romilast be used for allergies?

Yes, Romilast is approved by the FDA for use in treating symptoms of season allergies, including sneezing, runny nose, and itchy or watery eyes.

How do I take Romilast?

Romilast is taken orally once a day with or without food. It should be taken at the same time each day. It is important to read the patient information leaflet for detailed instructions on how to take Romilast.

Can Romilast be used to treat sinus infections?

Romilast is approved for the treatment of symptoms of season allergies. While it may help relieve some of the symptoms associated with a sinus infection, it is not approved for the treatment of sinus infections.

What is the difference between Romilast and Fluticasone?

Romilast is a prescription medication used to prevent asthma attacks and relieve symptoms of season allergies. Fluticasone is a prescription medication used to treat inflammation and swelling of the airways caused by asthma and other breathing disorders.

What is Romilast sodium?

Romilast sodium is the active ingredient in the prescription medication Romilast. It belongs to a class of drugs known as leukotriene receptor antagonists, which help to prevent asthma attacks and relieve symptoms of season allergies.

How long should I take Romilast for?

The duration of treatment with Romilast should be determined by your healthcare provider. For most patients, Romilast is taken on a daily basis. You should not stop taking Romilast without consulting your doctor.

Can Romilast cause chest tightness?

Chest tightness is a possible side effect of taking Romilast. It is important to contact your doctor immediately if you experience chest tightness while taking Romilast.

Is Romilast available in other forms?

Romilast is available in tablets, chewable tablets, granules, and oral suspension. Your doctor will advise on the form and dosage that is most appropriate for you.

Does Romilast have any interactions with other drugs?

Yes, Romilast may interact with certain medications. Before taking any new medications, including over-the-counter drugs, it is important to speak with your doctor or pharmacist.