Locular
Locular Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Locular is a brand name. Its generic name is Brimonidine.
Introduction
Locular is a medication prescribed for treating ocular hypertension and glaucoma and also used for cosmetic purposes. It can decrease intraocular pressure (IOP) and improve blood flow to the optic nerve.Uses
Locular is used to reduce intraocular pressure (IOP) in those with primary open-angle glaucoma or ocular hypertension. It can also be used cosmetically to improve dark circles, wrinkles, and puffiness under the eyes.Mechanism of Action
Locular works by constricting blood vessels. By reducing blood flow, it reduces the pressure in the eye and lowers IOP. It also has neuroprotective effects that help preserve the optic nerve.How Long Does it Take to Work?
It usually takes about three hours for brimonidine to reach its full effect. It will then remain in the eye for about six hours before it begins to be metabolized and eliminated.Absorption, Route of Elimination, Dosage, Administration, Side Effect, Toxicity
Locular is rapidly and almost completely absorbed into the bloodstream after application to the eye. Locular is eliminated primarily in the form of its metabolites via the renal route. The recommended dose is one drop applied two times daily to the affected eye(s). Common side effects of brimonidine include blurred vision, dry eyes, redness of the eyes, itching, burning, and stinging in the eyes. Serious potential side effects include abnormal flashes of light, eye pain, and changes in vision. Locular can be toxic if ingested, and can cause serious and potentially fatal central nervous system complications.Precautions, Interactions, Disease Interactions, Drug Interactions, Food Interactions, Pregnancy Use, Lactation Use, Acute Overdose, Contraindications, Use Directions, Storage Conditions
Locular should not be used if you have allergies to any of its ingredients. It should also not be used if you have gastric or duodenal ulcers, blood pressure related problems, heart issues, or kidney issues. It should be used with caution in patients with suspected or diagnosed glaucoma, and it may interact with other medications. Therefore, it is important to tell your doctor about all the medications you are taking. Food interactions are not known; however, food interactions may occur when the drug is taken in conjunction with other medications. Therefore, you should avoid taking any other medications within 2 hours of taking brimonidine. Locular should not be used in pregnancy. There is currently not enough information available on the safety of the drug during lactation and it is recommended that it not be used during this period. An acute overdose of brimonidine can cause a dangerous drop in blood pressure, and can lead to cardiovascular collapse. If an overdose is suspected, the patient should seek medical attention right away. Locular is contraindicated in patients with known hypersensitivity to either of its components. When using brimonidine, the solution should always be applied to the eye once per day or two times daily, as prescribed by your doctor. The eyes should not be touched by the applicator tip, and the bottle should be discarded after 28 days. Locular should be stored at controlled room temperature and it should be kept away from extreme heat or cold temperatures, direct sunlight, and moisture.Volume of Distribution, Half Life, Clearance
The apparent volume of distribution of brimonidine is 31L. Its half-life is 2.5 hours, and its clearance rate is 10mL/min.Here you find in details version of Locular
Some Frequently Asked Questions About Locular
What is Locular?
Locular is a medication used for the treatment of glaucoma and ocular hypertension. It works by decreasing the production of fluid in the eye, thus reducing intraocular pressure.
What is the brand name for Locular?
The brand name for Locular is Alphagan®.
How often should I take Locular?
Locular is usually taken twice a day, unless otherwise directed by your doctor.
What should I do if I miss a dose of Locular?
If you miss a dose of Locular, take your next dose as soon as you remember. However, if it is close to the time for your next scheduled dose, skip the missed dose and take your next dose as scheduled.
What are the side effects of Locular?
The most common side effects of Locular include blurred vision, dry mouth, fatigue, headache, and conjunctival redness and irritation. Tell your doctor if any of these symptoms do not go away or become bothersome.
Is Locular safe for pregnant women?
Locular has not been studied in pregnant women. Women who are pregnant or are planning on becoming pregnant should discuss the risks and benefits with their doctor before using this medication.
What should I do if I experience an allergic reaction to Locular?
If you experience an allergic reaction to Locular, stop taking the medication and contact your doctor as soon as possible. Common signs of an allergic reaction include itching, swelling, rash, hives, chest tightness, and difficulty breathing.
Is Locular habit forming?
Locular is not habit forming. However, it is important to take the medication exactly as prescribed by your doctor.
What are the common interactions with Locular?
Locular may interact with other medications. It is important to tell your doctor about all medications, vitamins, and supplements that you are taking before starting Locular. Examples of medications that may interact with Locular include MAO inhibitors, beta blockers, diuretics, and ACE inhibitors.
Can Locular be used for other conditions?
Locular is only approved by the FDA for treating glaucoma and ocular hypertension. It should not be used for any other purpose without the approval of a doctor.
Can Locular cause vision problems?
Locular can cause vision changes such as blurred vision and decreased night vision. If you experience vision changes, contact your doctor immediately.
Can Locular be used in children?
Locular has not been studied in children and should not be used in anyone under 18 years of age.
What are the storage instructions for Locular?
Locular should be stored at room temperature, away from direct light and moisture. Keep the medication away from children and pets.
Is Locular covered by insurance?
Coverage of Locular depends on individual insurance plans. It is important to check with your insurance provider to determine coverage and cost.
Is Locular available in generic form?
No, Locular is only available in brand name form. There is no generic form available.
How quickly does Locular work?
Locular works quickly to reduce intraocular pressure. The full effects of the medication may take up to four hours after it is taken.
Can I drive after taking Locular?
Locular can cause blurred vision and drowsiness, which may make it difficult to drive. You should not drive or operate machinery until you know how the medication affects you.
Do I need to take Locular with food?
No, Locular can be taken with or without food.
Can Locular be used for long-term treatment?
Yes, Locular can be used for long-term treatment of glaucoma and ocular hypertension. It is important to take the medication exactly as prescribed by your doctor.
What is the usual dose of Locular?
The usual dose of Locular is one drop in each affected eye twice a day, unless otherwise directed by your doctor.
Are there any foods or drinks to avoid while taking Locular?
There are no foods or drinks that should be avoided while taking Locular. However, you should not wear contact lenses while using this medication.
Can Locular cause an upset stomach?
It is possible for Locular to cause an upset stomach, however this is not a common side effect. Tell your doctor if you experience upset stomach while taking this medication.
What are the risks of using Locular?
The most common risks associated with Locular include blurred vision, dry mouth, fatigue, headache, and conjunctival redness and irritation. Long-term use can result in increased eye pressure or intraocular inflammation. Tell your doctor if any of these symptoms occur.
What should I do if I experience eye pain while taking Locular?
If you experience eye pain while taking Locular, contact your doctor immediately. You may have an underlying eye condition that needs treatment.
Does Locular interact with any other medications?
Yes, Locular can interact with other medications. Examples of medications that may interact with Locular include MAO inhibitors, beta blockers, diuretics, and ACE inhibitors. Be sure to tell your doctor about all medications, vitamins, and supplements that you are taking before starting Locular.
Should I avoid wearing contact lenses while taking Locular?
Yes, you should avoid wearing contact lenses while taking Locular. This medication may cause blurred vision or other vision changes that can make it difficult to wear contact lenses.
How should I dispose of unused Locular?
Unused or expired Locular should be disposed of according to your doctor or pharmacist’s instructions. Do not flush medication down the toilet, drain, or throw it away.
What should I do if I experience side effects from Locular?
If you experience side effects from Locular, tell your doctor as soon as possible. Depending on the type and severity of the side effect, your doctor may suggest a change in dosage or a different medication.
Does Locular cause weight gain?
Weight gain is not a common side effect of Locular. However, if you are concerned about weight gain while taking this medication, it is best to discuss with your doctor.
Can I consume alcohol while taking Locular?
It is not recommended to consume alcohol while taking Locular, as alcohol can increase the side effects of the medication. Talk to your doctor about the risks and benefits of drinking alcohol while taking Locular.
Is Locular safe for people with liver disease?
Locular is not recommended for people with liver disease. It is important to tell your doctor about any existing medical conditions you have before taking Locular.
What should I avoid while taking Locular?
You should avoid wearing contact lenses while taking Locular and you should also avoid driving or operating machinery until you know how the medication affects you.
Can Locular be taken with other eye medications?
It is important to tell your doctor about all other eye medications or supplements you are taking before starting Locular. Taking two or more medications at the same time can increase the risk of side effects.
What is the maximum dose of Locular?
The maximum recommended dose of Locular is two drops in each affected eye twice a day. Taking more than the prescribed amount can increase the risk of side effects.
Can Locular be used to treat other eye conditions?
Locular is only approved for treating glaucoma and ocular hypertension. It should not be used to treat any other eye condition without the approval of your doctor.
Do I need to get periodic eye exams while taking Locular?
Yes, it is important to get periodic eye exams while taking Locular. Your doctor may suggest additional tests or treatments depending on the results of the eye exams.
Will Locular affect my ability to wear contact lenses?
Locular may cause blurred vision or other vision changes, which can make it difficult to wear contact lenses. Your doctor can recommend ways to minimize any discomfort while wearing contact lenses.
When should I expect to see the effects of Locular?
The full effects of Locular generally occur within four hours of taking the medication. If no effect is seen, contact your doctor for further instruction.
Are there any over-the-counter medications that can be taken with Locular?
It is important to tell your doctor about all over-the-counter medications you are taking before starting Locular. Some over-the-counter medications may interact with Locular and increase the risk of side effects.
Are there any foods or supplements that should be avoided while taking Locular?
It is important to discuss all prescription and non-prescription medications, vitamins, and supplements with your doctor before taking Locular. Some supplements can interact with Locular and increase the risk of side effects.
What should I do if I experience dry mouth while taking Locular?
Dry mouth is a common side effect of Locular. If this occurs, drinking plenty of water can help relieve the symptoms. However, if the symptoms do not go away or become bothersome, contact your doctor.