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গ্যাটসিনা (চোখের ড্রপ)

By Ibn-Sina Pharmaceuticals Ltd.

Weight: 0.5%

Unit Price: 140

Last Updated: 2019-11-05 09:25:23

গ্যাটসিনা চোখের ড্রপ এর কাজ

Gatifloxacin eye drops is indicated for the treatment of bacterial conjunctivitis caused by susceptible strains of the following organisms: 

  • Aerobic Gram-Positive Bacteria: Corynebacterium propinquum, Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus mitis, Streptococcus pneumoniae
  • Aerobic Gram-Negative Bacteria: Haemophilus influenzae.

গ্যাটসিনা জেনারিক

Gatifloxacin (Ophthalmic Solution)

গ্যাটসিনা পরিচিতি

The antibacterial action of gatifloxacin results from inhibition of DNA gyrase and topoisomerase IV. DNA gyrase is an essential enzyme that is involved in the replication, transcription and repair of bacterial DNA. Topoisomerase IV is an enzyme known to play a key role in the partitioning of the chromosomal DNA during bacterial cell division. The mechanism of action of fluoroquinolones including gatifloxacin is different from that of aminoglycoside, macrolide, and tetracycline antibiotics. Therefore, gatifloxacin may be active against pathogens that are resistant to these antibiotics and these antibiotics may be active against pathogens that are resistant to gatifloxacin. There is no crossresistance between gatifloxacin and the aforementioned classes of antibiotics. Cross resistance has been observed between systemic gatifloxacin and some other fluoroquinolones. Resistance to gatifloxacin in vitro develops via multiple-step mutations.

গ্যাটসিনা চিকিত্সাবিদ্যাগত শ্রেণী

Ophthalmic antibacterial drugs

গ্যাটসিনা চোখের ড্রপ খাওয়ার নিয়ম

0.3% eye drops-

The recommended dosage regimen for the treatment of bacterial conjunctivitis is: 

  • Days 1 and 2: Instill one drop every two hours in the affected eye(s) while awake, up to 8 times daily.
  • Days 3 through 7: Instill one drop up to 4 times daily while awake.

0.5% eye drops-

Patients 1 year of age or older: Instill one drop every two hours in the affected eye(s) while awake, up to 8 times on Day 1. Instill one drop two to four times daily in the affected eye(s) while awake on Days 2 through 7.

গ্যাটসিনা এর প্রয়োগ-পদ্ধতি

গ্যাটসিনা চোখের ড্রপ এর পার্শ্বপ্রতিক্রিয়া

The most frequently reported adverse events in the overall study population were conjunctival irritation, increased lacrimation etc.

গ্যাটসিনা ব্যবহারে সতর্কতা

Patients should be advised not to wear contact lenses if they have signs and symptoms of bacterial conjunctivitis. Avoid contaminating the applicator tip with material from the eye, fingers or other source.

গ্যাটসিনা এর প্রতিক্রিয়া

Specific drug interaction studies have not been conducted with gatifloxacin eye drops. However, the systemic administration of some quinolones has been shown to elevate plasma concentrations of theophylline, interfere with the metabolism of caffeine, and enhance the effects of the oral anticoagulant warfarin and its derivatives, and has been associated with transient elevations in serum creatinine in patients receiving systemic cyclosporine concomitantly.

গ্যাটসিনা গর্ভকালীন কিংবা দুগ্ধদানকালীন অবস্থায় ব্যবহার

Pregnancy Category C. Because there are no adequate and well-controlled studies in pregnant women, Gatifloxacin 0.3% eye drops should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. 

Lactation: It is not known whether this drug is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when Gatifloxacin is administered to a nursing woman.

গ্যাটসিনা মাত্রাতিরিক্ত সেবনের প্রতিক্রিয়া

An overdose of this medication is unlikely to threaten life.

গ্যাটসিনা এর প্রতিনির্দেশনা

Gatifloxacin eye drops is contraindicated in patients with a history of hypersensitivity to Gatifloxacin, to other quinolones, or to any of the components in this medication. Gatiflox 0.3% eye drops should not be injected subconjunctivally, nor should it be introduced directly into the anterior chamber of the eye.

গ্যাটসিনা এর ব্যবহারবিধি

 

গ্যাটসিনা সংরক্ষণ

Store in a cool and dry place, away from light. Keep out of reach of children.

গ্যাটসিনা এর বিশেষ সতর্কতা

Geriatric Use: No overall differences in safety or effectiveness have been observed between elderly and younger patients.

গ্যাটসিনা এর অন্যান্য ঔষধের সাথে প্রতিক্রিয়া