Extracef

Extracef Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Extracef is a brand name. Its generic name is Cefradine.

Introduction

Extracef is an antibiotic drug commonly used for treatment of infections caused by bacteria. It is a first-generation cephalosporin and belongs to the class of cephalosporins. It is a semi-synthetic antibiotic, which means that it has been made in a laboratory from natural substances.

Uses for

Extracef is used to treat a variety of infections, including but not limited to respiratory infections, skin infections, chest infections, urinary tract infections, and some sexually transmitted diseases.

Mechanism of Action

Extracef works by inhibiting the bacteria's ability to make proteins which are an important part of its structure, function, and multiplication. By inhibiting this process, cefradine is able to kill the bacteria and prevent it from multiplying.

How Long Does it Take to Work?

Extracef usually starts to work within a few hours of taking the medication. However, depending on the type of infection being treated, it can take up to several days before the symptoms start to clear up.

Absorption

Extracef is mostly absorbed from the gastrointestinal tract, with the exception of the dose taken rectally. The majority of an oral dose is absorbed within 3 hours, with peak plasma concentrations occurring after 4-6 hours.

Route of Elimination

Extracef is eliminated largely from the urine as the unchanged form. Some is also excreted in the feces via biliary excretion. The half-life is in the range of 1-2 hours.

Dosage

Extracef is available in the form of tablets, capsules, and soluble tablets. The usual adult dosage ranges from 500mg to 1000mg twice daily, depending on the severity of the infection being treated.

Administration

Extracef should be taken orally with a glass of water, preferably one hour before or two hours after meals, or as directed by the healthcare provider. It is important not to take cefradine with food as this interferes with absorption. For rectal administration, the dose should be dissolved in a small amount of water.

Side Effect

Common side effects of cefradine include nausea, vomiting, abdominal pain, diarrhea, skin rash, oral thrush, and vaginal itching. More serious side effects include anemia, jaundice, fever, and seizures.

Toxicity

Extracef is generally safe and well tolerated at the recommended dosage. Overdose can lead to symptoms such as renal failure, seizures, and blood disorders.

Precautions

Extracef should be used with caution in patients with liver or kidney disease, and in those taking other medications such as anticoagulants, oral contraceptives, and diuretics. It should also be used with caution in pregnant and breastfeeding women.

Interactions

Extracef may interact with other drugs and should not be taken in combination with other antibiotics, sedatives, or anticoagulants. It also interacts with some herbs and supplements, including ginkgo biloba, garlic, and St. John's Wort.

Disease Interaction

Extracef has been known to interact with certain diseases, including kidney and liver disease, which may affect its effectiveness or cause side effects. It may also interact with other diseases, such as diabetes, which can alter its metabolism and increase its potential for side effects.

Drug Interactions

Extracef may interact with other drugs including anticoagulants, oral contraceptives, and diuretics. Taking cefradine simultaneously with these drugs may increase the risk of side effects. Additionally, cefradine may increase the risk of bleeding when taken with other drugs that increase blood clotting time.

Food Interactions

Extracef should be taken one hour before or two hours after meals. Taking it simultaneously with food may reduce its effectiveness. It should also not be taken with dairy products, including milk, cheese, and yogurt, as this may reduce its absorption rate.

Pregnancy Use

Extracef should be used with caution in pregnant women. There is limited evidence regarding the safety of cefradine during pregnancy. If used, the lowest effective dosage should be used for the shortest duration possible.

Lactation Use

Extracef should be avoided during lactation as it is excreted in breast milk. If it must be used, the lowest effective dosage should be used for the shortest duration possible.

Acute Overdose

If an overdose is suspected, the patient should be taken to the doctor or hospital immediately. Symptoms of an overdose include nausea, vomiting, abdominal pain, drowsiness, convulsions, and sweating.

Contraindication

Extracef is contraindicated in patients with a known hypersensitivity to cephalosporins or penicillins. It is also contraindicated in patients with severe renal or hepatic impairment, and in those who have had a previous episode of either anaphylactic or anaphylactoid reactions.

Use Direction

Extracef should always be taken as prescribed by the doctor. The dosing frequency and duration of treatment should not be altered without consulting the healthcare provider.

Storage Condition

Extracef should be stored at room temperature in a closed container, away from moisture and direct sunlight. Keep out of reach of children and pets.

Volume of Distribution

Extracef has a volume of distribution of 0.3-0.6 L/kg indicating a low penetration into tissues.

Half Life

The elimination half-life of cefradine is in the range of 1-2 hours.

Clearance

Extracef is mainly eliminated by the kidneys with an average clearance of 250mL/min.

Here you find in details version of Extracef

Some Frequently Asked Questions About Extracef

What is Extracef?

Extracef is a type of antibiotic medicine that is used to treat bacterial infections.

How does Extracef work?

Extracef works by preventing bacteria from forming cell walls, which are necessary for the bacteria to survive and grow.

What type of infections can Extracef treat?

Extracef is used to treat bacterial infections such as skin and soft tissue infections, urinary tract infections, and respiratory tract infections.

Who should not take Extracef?

Extracef should not be taken by people who are allergic to cephalosporin antibiotics. People with kidney, liver, or intestinal disease should consult a doctor before taking this medicine.

What are the possible side effects of Extracef?

The most common side effects of Extracef are nausea, vomiting, diarrhea, skin rash, and headache.

Is Extracef safe to take during pregnancy?

Extracef is generally considered safe to take during pregnancy, however it is recommended that pregnant women should consult their doctor before taking it.

What should I do if I experience any side effects from Extracef?

If you experience any side effects, you should stop taking the medication and consult your doctor immediately.

How and when should I take Extracef?

Extracef should be taken with food or a full glass of water/milk. The amount and duration of treatment will depend on the type and severity of your infection.

What should I do if I miss a dose of Extracef?

If you miss a dose of Extracef, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and continue your regular dosing schedule.

Is it safe to consume alcohol while taking Extracef?

It is not recommended to consume alcohol while taking Extracef as it may increase the risk of side effects such as nausea, dizziness, drowsiness, and reduced alertness.

Can I take other medicines while taking Extracef?

Some medicines may interact with Extracef and it is recommended to consult your doctor before taking any other medication.

Can Extracef be used for children?

Extracef can be used for children but it is important to consult a doctor before giving this medicine to a child.

Are there any foods I should avoid while taking Extracef?

No, you do not need to avoid any specific foods while taking Extracef.

How long does it take for Extracef to work?

It may take up to 2 weeks for Extracef to work and start relieving symptoms.

Can I stop taking Extracef once I start to feel better?

No, it is important to continue taking Extracef until you have finished the course of medication prescribed by your doctor.

What should I do if I am taking Extracef and experience a fever?

If you experience a fever while taking Extracef, you should contact your doctor as soon as possible.

Does Extracef interact with birth control pills?

Yes, Extracef may interact with birth control pills. It is recommended to consult your doctor for advice.

Does Extracef interact with other antibiotics?

Yes, some antibiotics may interact with Extracef. It is recommended to consult your doctor for advice before taking any other medication.

Should I take Extracef with food or on an empty stomach?

Extracef should be taken with food or a full glass of water/milk.

Can Extracef be used to treat a sore throat?

Yes, Extracef is used to treat sore throat caused by bacterial infections.

Can I take Extracef to prevent an infection?

No, Extracef should not be taken as a preventative measure against infections.

Is Extracef affected by hot weather?

No, Extracef is not affected by hot weather.

Can Extracef be taken with vitamin supplements?

Yes, Extracef can be taken with vitamin supplements, however it is recommended to consult your doctor before taking any additional supplements.

What should I do if I experience an allergic reaction to Extracef?

If you experience an allergic reaction to Extracef, stop taking the medication and contact your doctor immediately.

Can I take Extracef with antacids?

Yes, Extracef can be taken with antacids, however it is recommended to consult your doctor for advice.

Can I take Extracef if I am breastfeeding?

It is not recommended to take Extracef while breastfeeding, however it is recommended to consult your doctor for advice.

Can I take Extracef while menstruating?

Yes, you can take Extracef while menstruating.

What should I do if I experience nausea after taking Extracef?

If you experience nausea after taking Extracef, it is recommended to consult your doctor for advice.

Can Extracef interact with other medications?

Yes, some medications may interact with Extracef and it is recommended to consult your doctor before taking any other medication.

What should I do if I experience vomiting after taking Extracef?

If you experience vomiting after taking Extracef, it is recommended to consult your doctor for advice.

Can I take Extracef if I am diabetic?

Yes, Extracef can be taken if you are diabetic, however it is recommended to consult your doctor for advice.

Can I take Extracef if I have a kidney condition?

Yes, Extracef can be taken if you have a kidney condition, however it is recommended to consult your doctor for advice.

Can I take Extracef if I have a liver condition?

Yes, Extracef can be taken if you have a liver condition, however it is recommended to consult your doctor for advice.

Is there any age restriction for taking Extracef?

No, there is no age restriction for taking Extracef, however it is recommended to consult your doctor for advice.

Can Extracef cause dizziness?

Yes, Extracef can cause dizziness, and it is recommended to consult your doctor if you experience this symptom.

Can Extracef cause drowsiness?

Yes, Extracef can cause drowsiness, and it is recommended to consult your doctor if you experience this symptom.

Can Extracef cause dehydration?

Yes, Extracef can cause dehydration, and it is recommended to consult your doctor if you experience this symptom.

Can Extracef cause reduced alertness?

Yes, Extracef can cause reduced alertness, and it is recommended to consult your doctor if you experience this symptom.

Can Extracef cause a burning sensation?

Yes, Extracef can cause a burning sensation, and it is recommended to consult your doctor if you experience this symptom.

Can Extracef cause headaches?

Yes, Extracef can cause headaches, and it is recommended to consult your doctor if you experience this symptom.

Can Extracef cause stomach cramps?

Yes, Extracef can cause stomach cramps, and it is recommended to consult your doctor if you experience this symptom.