Eletam

Eletam Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Eletam is a brand name. Its generic name is Levetiracetam.

Eletam Introduction

Eletam (Keppra) is an anti-epileptic medication that is used to treat certain types of seizures in adults and children. It is used as an adjunct therapy to treat partial onset seizures and primary generalized tonic-clonic seizures. It works by reducing the activity of the neurons that cause seizures.

Uses for Eletam

Eletam is used to treat partial onset seizures and secondarily generalized tonic-clonic seizures in adults and children four years of age and older. It can also be used in patients who are at risk of further seizures.

Mechanism of Action

Eletam works by binding to a specific receptor in the brain, known as the SV2A receptor. This binding action reduces the amount of glutamate, an excitatory neurotransmitter, and increases the amount of GABA, an inhibitory neurotransmitter. This action is believed to reduce the activity of neurons that cause seizures.

How Long Does It Take To Work?

The effects of levetiracetam can be seen within one to two weeks of starting the medication. Approximately 50-70% of patients will experience a reduction in seizure frequency within six weeks of starting the medication.

Absorption

Eletam is quickly and completely absorbed from the gastrointestinal tract following oral administration.

Route of Elimination

Eletam is primarily metabolized in the liver by enzymes to its active metabolites. Most of the drug is eliminated in the urine and some in the feces.

Dosage

Dosage requirements for levetiracetam vary depending on the type and severity of the seizure disorder. In general, the recommended dosage for adults is 1000-3000 mg/day taken in two or three divided doses. For children ages four years and older, the dose is 10-50 mg/kg/day divided into two or three doses.

Administration

Eletam is taken orally as a tablet, oral solution or IV solution.

Side Effects

Common side effects of levetiracetam include drowsiness, dizziness, asthenia, headache, vertigo, somnolence, fatigue, and irritability. Other more serious side effects can include psychosis, aggression, and ideation.

Toxicity

At recommended doses, levetiracetam is considered safe and well tolerated. At higher doses, there is potential for a decrease in plasma levels of folate and vitamin B12 and a decrease in red blood cell count (anemia). There is also potential for reversible increases in serum transaminase levels.

Precautions

Patients should be monitored for changes in behavior, including signs of depression or suicidal ideation. Patients should also be monitored for signs of kidney failure and monitored for drugs that interact with levetiracetam.

Interactions

Eletam may interact with other medications and should not be taken with certain drugs, such as phenytoin, phenobarbital, rifampicin, and lamotrigine.

Disease Interaction

Eletam can be used safely in patients with kidney or liver impairment. It can also be used in patients with depression or anxiety.

Drug Interaction

Eletam can interact with other drugs including anticonvulsants, antidepressants and certain antibiotics.

Food Interactions

Eletam can be taken with or without food. It is best taken with food to help reduce stomach upset.

Pregnancy Use

Eletam is classified as Pregnancy Category C. The safety of levetiracetam in pregnancy has not been firmly established and it is not recommended for pregnant women, except if the potential benefit outweighs the potential risk.

Lactation Use

Eletam is excreted in the milk of lactating mothers. It is not recommended for use in breastfeeding mothers.

Acute Overdose

No specific antidote is available for overdose with levetiracetam. Symptoms of overdose may include sedation, nausea, vomiting, and unsteadiness. Treatment should be supportive and symptomatic and adlibitum fluid should be incorporated.

Contraindication

Eletam is contraindicated in patients with an allergy to levetiracetam or any of its components.

Use Directions

Eletam should be taken as directed by your healthcare provider. The dosage requirements may vary depending on the type and severity of the seizure disorder.

Storage Condition

Eletam should be stored at room temperature away from moisture and heat.

Volume of Distribution

The volume of distribution for levetiracetam is 0.5-1.0 L/kg.

Half Life

The half-life of levetiracetam is 6-8 hours.

Clearance

Eletam is cleared by the kidney and the elimination half-life is unaffected by renal impairment. The renal clearance is 0.19-0.42 L/h.

Here you find in details version of Eletam

Some Frequently Asked Questions About Eletam

What is Eletam?

Eletam is a medication used to treat certain types of seizures in people with epilepsy. It is also approved for the treatment of myoclonic seizures and is sometimes used off-label to treat other types of seizure disorders.

How does Eletam work?

Eletam works on the central nervous system (CNS) to help reduce the frequency of seizures. It works by acting on certain voltage-dependent sodium channels in the brain, which helps to stabilize the neural membranes and inhibit seizure activity.

Does Eletam have any side effects?

Yes, Eletam can cause side effects, including dizziness, confusion, fatigue, nausea, and irritability. It can also cause difficulty sleeping, weight gain, and headaches.Talk to your doctor if you experience any severe or worrisome side effects.

What is the proper dosage for Eletam?

The proper dosage for Eletam depends on your specific condition. Your doctor will determine what dosage is appropriate for you based on your age, weight, overall health, and medical history. It is important to always take Eletam as prescribed.

Can I take Eletam with other medications?

It is important to always consult your doctor or pharmacist before taking any medications, including Eletam. Always discuss any other medications you are taking to ensure that Eletam will not interact with them.

How quickly does Eletam start working?

The effects of Eletam may begin to be felt within one hour of taking the medication. However, it may take several days or weeks for the full effects to become noticeable.

Can I drink alcohol while taking Eletam?

It is not recommended to drink alcohol while taking Eletam, as the combination can increase the risk of drowsiness and confusion. Talk to your doctor if you are concerned about combining alcohol and Eletam.

Does Eletam help with anxiety?

While Eletam is primarily used to treat seizures, it may have a calming effect on people with anxiety. However, it is best to speak with your doctor to determine if Eletam is an appropriate treatment for your anxiety.

Does Eletam cause weight gain?

Eletam can cause weight gain in some patients. Talk to your doctor if you are concerned about the potential for weight gain.

Can Eletam be used to treat status epilepticus?

Yes, Eletam can be used to treat status epilepticus, a life-threatening condition that requires immediate medical attention. If you are experiencing a seizure that does not stop, seek medical help right away.

Can Eletam be used to treat bipolar disorder?

Eletam is not approved for the treatment of bipolar disorder. However, it may be used off-label for that purpose. Talk to your doctor to determine if Eletam may be an appropriate treatment for your bipolar disorder.

What are the most common side effects of Eletam?

The most common side effects of Eletam include dizziness, confusion, fatigue, nausea, and irritability. It can also cause difficulty sleeping, weight gain, and headaches. Talk to your doctor if you experience any severe or worrisome side effects.

What is the difference between Eletam and other antiseizure medications?

Eletam is a unique antiseizure medication, as it works on the central nervous system (CNS) to help reduce the frequency of seizures. It works by acting on certain voltage-dependent sodium channels in the brain, which helps to stabilize the neural membranes and inhibit seizure activity. Other antiseizure medications work on different parts of the brain or in different ways.

Is Eletam safe for children?

Eletam is approved for use in pediatric patients aged 4 years and older. Talk to your doctor before giving Eletam to a child to determine if it is an appropriate treatment for their condition.

How long does it take for Eletam to reach its full effectiveness?

It can take several days or weeks for Eletam to reach its full effectiveness. However, it is important to take the medication as directed by your doctor to ensure best results.

Is Eletam addictive?

No, Eletam is not regarded as an addictive medication. However, it may cause psychological or physical dependence, so it is important to take the medication as prescribed and to follow your doctor's instructions.

Can Eletam cause seizures?

Eletam is used to treat seizures, so it is unlikely to cause seizures. However, if it is not taken as prescribed it may increase the risk of seizures.

What is the usual dose of Eletam?

The usual dose of Eletam depends on your specific condition. Your doctor will determine what dosage is appropriate for you based on your age, weight, overall health, and medical history.

Is Eletam safe for pregnant women?

Eletam is classified as a Pregnancy Category C medication, meaning it is not known if it is safe to use during pregnancy. Talk to your doctor to determine whether Eletam is an appropriate treatment for you during pregnancy.

What should I do if I miss a dose of Eletam?

If you miss a dose of Eletam, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take more Eletam than prescribed by your doctor.

What are the possible drug interactions for Eletam?

Eletam has been known to interact with certain medications, such as birth control pills, cimetidine, and antidepressants. Talk to your doctor or pharmacist before taking any medications in combination with Eletam to ensure that no serious interactions occur.

Can Eletam cause depression?

Eletam can cause side effects such as confusion, fatigue, and irritability, which can make depression worse in some patients. If you have a history of depression, talk to your doctor about possible side effects associated with Eletam.

What should I do if I experience an allergic reaction to Eletam?

If you experience an allergic reaction after taking Eletam, such as hives, rash, swelling, or difficulty breathing, seek medical attention right away. Stop taking the medication and let your doctor know immediately.

Can Eletam be taken with food?

Eletam can be taken with or without food. However, it is recommended to take it with food to reduce the risk of upset stomach.

How long does it take for Eletam to start working?

The effects of Eletam may begin to be felt within one hour of taking the medication. However, it may take several days or weeks for the full effects to become noticeable.

Can Eletam be used to treat other seizure disorders?

Eletam has only been approved to treat certain types of seizures in people with epilepsy. However, it may be used off-label to treat other types of seizure disorders.

How is Eletam administered?

Eletam is available in an oral tablet, oral solution, and intravenous (IV) injection. The form and dosage will depend on your condition and individual needs. Talk to your doctor or pharmacist to determine the best form and dosage for you.

Can Eletam be used for long-term seizure prevention?

Yes, Eletam can be used long-term for seizure prevention. However, it is important to discuss the risks and benefits of taking Eletam with your doctor before starting long-term treatment.

What should I do if I forget to take my Eletam dose?

If you forget to take your Eletam dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take more Eletam than prescribed by your doctor.

Are there any lifestyle changes I should make while taking Eletam?

It is important to make healthy lifestyle changes while taking Eletam, such as avoiding alcohol, getting regular exercise, and eating a balanced diet. Talk to your doctor about any lifestyle changes you can make to improve the effectiveness of Eletam.

Can Eletam cause headaches?

Eletam can cause headaches in some patients. Talk to your doctor if you experience frequent or severe headaches while taking Eletam.

Can I break a Eletam tablet in half?

No, it is not recommended to break or crush a Eletam tablet. Doing so could increase the risk of serious side effects. Talk to your doctor or pharmacist for instructions on taking Eletam properly.

Is Eletam safe for the elderly?

Eletam is approved for use in elderly patients aged 4 years and older. It is important to discuss the benefits and risks of taking Eletam with your doctor before starting treatment.

Can Eletam cause liver damage?

Eletam can cause abnormal liver functioning test results, but it is not known to cause permanent liver damage. However, if you experience any unusual symptoms or side effects, talk to your doctor.

What should I do if Eletam does not seem to be working?

If you feel that Eletam is not working properly, it is important to talk to your doctor. Your doctor may recommend adjusting your Eletam dosage or switching to a different seizure medication.

Can Eletam cause birth defects?

Eletam has not been shown to cause birth defects in studies. However, it is classified as a Pregnancy Category C medication, meaning it is not known if it is safe to use during pregnancy. Talk to your doctor to discuss the risks of taking Eletam while pregnant.

Is Eletam safe for breastfeeding mothers?

Eletam is not known to be safe or unsafe during breastfeeding. If you are breastfeeding, talk to your doctor to determine if Eletam is an appropriate treatment for your condition.

Can Eletam cause memory loss?

Eletam can cause cognitive impairment, confusion, and difficulty concentrating, which may lead to memory loss. If you experience any changes in cognition, talk to your doctor.

Does Eletam make you sleepy?

Eletam may cause sleepiness and fatigue in some patients. It is important to use caution while performing tasks that require alertness, such as driving or operating machinery, until you know how Eletam affects you.

Can children take Eletam?

Eletam is approved for use in pediatric patients aged 4 years and older. Talk to your doctor before giving Eletam to a child to determine if it is an appropriate treatment for their condition.

What should I do if I think I am having an adverse reaction to Eletam?