Amoctin Tablet

Brand Name: Amoctin
Generic: Nitrazepam
Weight: 5 mg
Type: Tablet
Therapeutic Class: Benzodiazepine hypnotics
Manufacturer: Skylab Pharmaceuticals Ltd.
Price: 0.84
Last Updated: 2020-11-22 18:15:00

Amoctin Tablet Uses

Amoctin Tablet contains Nitrazepam. Amoctin uses:

Short-term management of insomnia, Infantile spasms

Amoctin Tablet Doses

Amoctin Tablet contains Nitrazepam 5 mg. Amoctin doses:

Short-term management of insomnia:

  • Adult: 5 mg at night; increase to 10 mg if necessary.
  • Elderly: and debilitated patients: ≤normal adult dose.

Infantile spasms:

  • Child: Infants: 125 mcg/kg bid; gradually increase to 250-500 mcg/kg bid.

May be taken with or without food

Side Effects

Hypotension, palpitation; agitation, aggressiveness, amnesia, ataxia, confusion, delusions, disorientation, dizziness, fatigue, hallucination, hangover, headache, irritability, nightmares, psychoses, rage, restlessness, sedation; rash; changes in libido; constipation, diarrhoea, excessive salivation, heartburn, nausea, vomiting; granulocytopenia, leukopenia; falling, muscle weakness; blurred or double vision; tinnitus (associated with withdrawal); aspiration, increased bronchial secretion, dyspnoea.


Nitrazepam is a benzodiazepine with a pronounced sleep-inducing activity. It depresses the reticular-activating system in the brainstem by enhancing the inhibitory effect of GABA on brain cells, thus preventing excessive brain activity.

Amoctin Precaution

May induce anterograde amnesia; caution patients to have uninterrupted sleep of 7-8 hr after ingestion of dose. May impair ability to drive or operate machinery. Depression, especially if suicidal risk may be present. History of drug abuse or acute alcoholism. Hepatic and renal impairment. Respiratory disease. Debilitated patients. Patients who are at risk of falls. Children, elderly. Pregnancy and lactation.


CNS depressant effect increased with alcohol, barbiturates, TCAs, phenothiazines, morphine derivatives. Effects may be antagonised by theophylline. Increased levels/effects with probenecid. Reduced levels/effects with rifampicin. May reduce effects of levodopa.

Pregnancy Lactation use

Category not classified


Myasthenia gravis, narrow-angle glaucoma, severe respiratory insufficiency, sleep apnoea syndrome, severe hepatic impairment, porphyria.

Special Warning


Acute Overdose

Symptoms: Somnolence, drowsiness, confusion, ataxia, impaired reflexes, coma, dyspnoea, hypotension, respiratory and cardiovascular depression. 

Management: Supportive. Gastric lavage may be beneficial if performed soon after ingestion. Flumazenil may reverse benzodiazepine-induced CNS depression.

Interaction with other Medicine


Storage Condition

Store at room temperature. Protect from light and moisture.

Amoctin Tablet price in Bangladesh 0.84