3-Geocef (Capsule)

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By Hallmark Pharmaceuticals Ltd.

Weight: 200 mg

Unit Price: 42

Last Updated: 2019-09-01 15:34:07

3-Geocef Capsule Uses

Cefixime is indicated in the following infectious diseases-

  • Respiratory Tract Infections: Pneumonia, Sinusitis, Pharyngitis and Tonsillitis, Acute Bronchitis and Acute Exacerbations of Chronic Bronchitis (AECB)
  • Otitis Media
  • Typhoid
  • Urinary Tract Infections
  • Uncomplicated gonorrhea (cervical/urethral).

3-Geocef Generic

Cefixime Trihydrate

3-Geocef Introduction

Cefixime binds to 1 or more of the penicillin-binding proteins (PBPs) which inhibit the final transpeptidation step of peptidoglycan synthesis in bacterial cell wall, thus inhibiting biosynthesis and arresting cell wall assembly resulting in bacterial cell death.

3-Geocef Therapeutic Class

Third generation Cephalosporins

3-Geocef Capsule Doses

The usual course of treatment is 7 days. This may be continued for up to 14 days if required. The daily dose can be given in 1–2 divided doses.Usual dose: 

  • Adult and child over 10 years: 200–400 mg daily
  • Child over 6 months: 8 mg/kg daily
  • 6 months to 1 year: 75 mg (3.75 ml) daily,
  • 1 to 4 years: 100 mg (5 ml) daily
  • 5 to 10 years: 200 mg (10 ml) daily

Typhoid and paratyphoid : 

  • Adult: 200 mg 12 hourly
  • Child: 10 mg/kg 12 hourly

Gonorrhoea: 

  • Adult: 400-800 mg as a single dose

3-Geocef Administrations

3-Geocef Capsule Side Effects

Cefixime is generally well tolerated. The majority of side-effects observed in clinical trials were mild and self-limiting in nature. Diarrhoea, stool changes, nausea, vomiting, abdominal pain, dyspepsia, headache and dizziness.

3-Geocef Precaution

Patient with history of penicillin allergy. Renal impairment. Children. Pregnancy and lactation.

3-Geocef Interaction

Increased prothrombin time (with or withot bleeding) with anticoagulants (e.g. warfarin). Increased plasma carbamazepine concentrations with concomitant use. Increased bioavailability with nifedipine. Increased serum concentration with probenecid.

3-Geocef Uses During Pregnancy

Pregnancy category B. There are no adequate and well-controlled studies in pregnant women. So this drug should be used during pregnancy only if clearly needed.

Use in Lactation: It is not known whether cefixime is excreted in human milk. So it is probably best either to avoid using the drug by the nursing mother or to discontinue breast feeding.

3-Geocef Accute Overdose

Symptoms: Mild to moderate adverse GI effects. 

Management: Supportive treatment. Empty stomach by gastric lavage.

3-Geocef Contraindication

Patients with known hypersensitivity to cephalosporin antibiotics, children under 6 months.

3-Geocef Uses Direction

 

3-Geocef Storage Condition

Store in a cool and dry place below 30ºC

3-Geocef Special Warning

Use in Children: Safety and effectiveness of cefixime in children aged less than 6 months have not been established. For children younger than 12 years or weighing less than 50 kg, the usual dose is 8 mg/kg/day.

Use in elderly:  No special precautions are necessary. Old age is not an indication for dose adjustment.

Dosage in renal impairment:

  • Creatinine clearance: 20 ml/min or greater: normal dose
  • Creatinine clearance: <20 ml/min or chronic ambulatory peritoneal dialysis
  • Haemodialysis: daily dose should not exceed 200 mg.

3-Geocef Interactions with other Medicine

 

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2017-08-31 20:16:49