Supirocin contains Mupirocin. Supirocin uses:

Supirocin ointment or cream is indicated for the topical treatment of impetigo due to Staphylococcus aureus and Streptococcus pyogenes. It is also indicated in folliculitis and furunculosis.

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Brand Name: Supirocin
Generic: Mupirocin
Weight: 2.0 %w/w
Type: Cream
Therapeutic Class: Topical Antibiotic preparations
Manufacturer: GLENMARK PHARMACEUTICALS
Price: 165.75
Last Updated: 2020-11-21 18:15:00

Doses

Supirocin contains Mupirocin 2.0 %w/w. Supirocin doses

Secondary skin infections:

  • Adult: As 2% cream: Apply to affected area three times daily for up to 10 days; re-evaluate after 3-5 days if no clinical response.
  • Child: ≥3 mth Same as adult dose.

Impetigo:

  • Adult: As 2% oint: Apply to affected area three times daily for 5-10 days; re-evaluate after 3-5 days if no clinical response.
  • Child: ≥2 mth Same as adult dose.

 

Side Effects

Burning, stinging, pruritus, pain, rash, erythema, dry skin, tenderness, cellulitis, pain or bleeding secondary to eczema, secondary wound infection, urticaria, swelling, increased exudates, contact dermatitis, furunculosis, exfoliative dermatitis. Rarely, systemic reactions (e.g. nausea, headache, dizziness, abdominal pain, ulcerative stomatitis, systemic allergic reactions).

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Introduction

Supirocin inhibits protein synthesis of the bacteria by binding to isoleucyl transfer ribonucleic acid (RNA)-synthetase. It has bacteriostatic properties at Min inhibitory concentrations and bactericidal properties at the higher concentrations.

Precaution

Supirocin is not suitable for ophthalmic or intra-nasal use. When Supirocin ointment is used on the face, care should be taken to avoid the eyes. In common with other polyethylene-based ointments, this drug should be used with caution if there is evidence of moderate or severe renal impairment. As with other antibacterial products, prolonged use may result in overgrowth of nonsusceptible organisms, including fung.

Interaction

Chloramphenicol may interfere with the antibacterial action of mupirocin in RNA synthesis.

Pregnancy Lactation use

Use in Pregnancy: Because animal studies are not always predictive of human response, this drug should be used during pregnancy only if clearly needed.

Use in lactation: It is not known whether this drug is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when Supirocin ointment is administered to a nursing woman.

Contraindication

This drug is contraindicated in individuals with a history of sensitivity reactions to Supirocin or any of the components of the preparation.

Special Warning

Pediatric Use: The safety and effectiveness of Supirocin ointment have been established in the age range of 2 months to 16 years. Use of the ointment in these age groups is supported by evidence from adequate and well-controlled studies of Supirocin in impetigo in pediatric patients.

Acute Overdose

 

Interaction with other Medicine

 

Storage Condition

Store at or below 25° C. Do not freeze.

Supirocin Cream price in India 165.75

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