Safenine Bio contains Mecobalamin. Safenine Bio uses:

Safenine Bio is indicated in-

  • Peripheral Neuropathies
  • Diabetic Neuropathy
  • Verteberal Syndrome
  • Nerve Compression Syndrome
  • Multiple sclerosis
  • Amyotrophic lateral sclerosis
  • Parkinson’s disease
  • Alzheimer’s disease
  • Diabetic retinopathy
  • Entrapment neuropathy
  • Drug induced neuropathy
  • Megaloblastic anemia due to Vitamin B12 deficiency
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Brand Name: Safenine Bio
Generic: Mecobalamin
Weight: 1500.0 Mcg
Type: Tablet
Therapeutic Class: Drugs for Megaloblastic Anemia
Manufacturer: MIGLIORE LIFE SCIENCES
Price: 90.1
Last Updated: 2020-11-20 18:15:00

Doses

Safenine Bio contains Mecobalamin 1500.0 Mcg. Safenine Bio doses

Tablet: The usual adult dosage is one 500 mcg tablet three times daily. The dosage should be adjusted according to the age of patient and the severity of symptoms. 

Injection:

  • Peripheral neuropathies: The usual adult dosage is one ampoule equivalent to 500 mcg of Safenine Bio, administered intramuscularly or intravenously three times a week.The dosage should be adjusted according to the age of patient and the severity of symptoms.
  • Megaloblastic anemia: The usual adult dosage is one ampoule equivalent to 500 mcg of Safenine Bio, administered intramuscularly or intravenously three times a week. After about two months of administration, dosage should be changed to one ampoule equivalent to 500 mcg of Safenine Bio every one to three months as maintenance therapy

 

Side Effects

Generally Safenine Bio is well tolerated. However, a few side effects like GI discomfort (including anorexia, nausea or diarrhea) & rash may be seen after administration of Safenine Bio.

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Introduction

Safenine Bio is the neurologically active form of vitamin B12 and occurs as a water-soluble vitamin in the body. It is a cofactor in the enzyme methionine synthase, which functions to transfer methyl groups for the regeneration of methionine from homocysteine. In anaemia, it increases erythrocyte production by promoting nucleic acid synthesis in the bone marrow and by promoting maturation and division of erythrocytes.

Precaution

The medicine should not be used for months if there is no response at all after its use for a certain period of time.

Interaction

Decreased GI tract absorption with neomycin, aminosalicylic acid, H2-blockers and colchicine. Reduced serum concentrations with oral contraceptives. Reduced effects in anaemia with parenteral chloramphenicol.

Pregnancy Lactation use

Not recommended during pregnancy & lactation.

Contraindication

Hypersensitivity to any component of this product.

Special Warning

Use in children: Not recommended.

Acute Overdose

 

Interaction with other Medicine

 

Storage Condition

Oral: Store at room temperature. Protect from moisture and light.

Parenteral: Store at room temperature. Do not expose to direct light.

Safenine Bio Tablet price in India 90.1

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