K Zpto Shampoo contains Ketoconazole. K Zpto Shampoo uses:
Treatment of superficial and deep mycoses:
Maintenance treatment to prevent recurrence in systemic mycotic infections and in chronic mucocutaneous candidiasis.Prophylactic treatment to prevent mycotic infection in patients with reduced host defenses, e.g., patients with cancer, organ transplant and burns.
|Brand Name:||K Zpto Shampoo|
|Therapeutic Class:||Drugs for subcutaneous and systemic mycoses|
|Manufacturer:||HBC DERMIZA HEALTHCARE PRIVATE LIMITED|
|Last Updated:||2020-11-21 18:15:00|
K Zpto Shampoo contains Ketoconazole 2.0 %. K Zpto Shampoo doses
Pityriasis versicolor, Skin fungal infections:
K Zpto Shampoo is very well tolerated. Nausea and itching may occasionally occur. In some patients, an idosyncratic liver reaction may occur (incidence 1 : 10,000).
K Zpto Shampoo interferes with biosynthesis of triglycerides and phopholipids by blocking fungal CYP450, thus altering cell membrane permeability in susceptible fungi. It also inhibits other fungal enzymes resulting in the accumulation of toxic concentrations of hydrogen peroxide.
Predisposition to adrenocortical insufficiency. Admin with acidic drink in patients with achlorhydria. Pregnancy and lactation.
Reduced absorption with antimuscarinics, antacids, H2-blockers, PPIs and sucralfate. Reduced plasma concentrations with rifampicin, isoniazid, efavirenz, nevirapine, phenytoin. May also reduce concentrations of isoniazid and rifampicin. May reduce efficacy of oral contraceptives. May increase serum levels of CYP3A4 substrates e.g. digoxin, oral anticoagulants, sildenafil, tacrolimus.
Category C: Either studies in animals have revealed adverse effects on the foetus (teratogenic or embryocidal or other) and there are no controlled studies in women or studies in women and animals are not available. Drugs should be given only if the potential benefit justifies the potential risk to the foetus.
Hypersensitivity; preexisting liver disease. Concurrent use with CYP3A4 substrates e.g. HMG-CoA reductase inhibitors (e.g. lovastatin, simvastatin), midazolam, triazolam, cisapride, dofetilide, eplerenone, nisoldipine, pimozide, quinidine, terfenadine, astemizole, ergot alkaloids (e.g. ergotamine, dihydroergotamine).
Renal Impairment: Oral: No dosage adjustment needed.
Hepatic Impairment: Oral: Contraindicated.
Store between 15-25° C. Protect from moisture and light.
K Zpto Shampoo price in India 191.25