Fbt contains Febuxostat. Fbt uses:
Fbt is indicated for the long-term management of Hyperuricemia in patients with gout. It is not recommended for use in the treatment of asymptomatic Hyperuricemia.
|Therapeutic Class:||Drugs used in Gout|
|Manufacturer:||CORONA REMEDIES PVT LTD|
|Last Updated:||2020-11-22 18:15:00|
Fbt contains Febuxostat 80.0 Mg. Fbt doses
The recommended starting dosage of Fbt is 40 mg once daily. For patients who do not achieve a serum uric acid concentration of less than 6 mg/dL after 2 weeks at the 40 mg dose, Fbt 80 mg once daily is recommended. Fbt can be administered without regard to food or antacid use.
The most common adverse events associated with the use of Fbt may include liver function abnormalities, nausea, arthralgia, and rash.
Fbt is a non-purine, selective xanthine oxidase (XO) inhibitor. It decreases serum uric acid level by inhibiting xanthine oxidase, which is responsible for uric acid production. Xanthine oxidase breaks down hypoxanthine to xanthine and thus to uric acid. Fbt is not expected to inhibit other enzymes involved in purine and pyrimidine synthesis and metabolism at therapeutic concentrations.
Gout Flare: An increase in gout flares is frequently observed during initiation of anti-hyperuricemic agents, including Fbt. If a gout flare occurs during treatment, Fbt need not be discontinued. Prophylactic therapy (i.e., non-steroidal anti-inflammatory drug (NSAID) or colchicine upon initiation of treatment) may be beneficial for up to six months.
Cardiovascular Events: A higher rate of cardiovascular thromboembolic events was observed in patients treated with febuxostat than allopurinol in clinical trials. Monitor for signs and symptoms of MI and stroke.
Liver Enzyme Elevation: Transaminase elevations have been observed in febuxostat -treated patients. Monitor liver function tests periodically.
Concomitant administration of Fbt with azathioprine, mercaptopurine or theophylline could increase plasma concentrations of these drugs resulting in severe toxicity.
Pregnancy Category C. There are no adequate and well-controlled studies in pregnant women. Fbt should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.
Lactation: It is not known whether this drug is excreted in human milk. Caution should be exercised when Fbt is administered to a nursing woman.
Fbt is contraindicated in patients being treated with azathioprine, mercaptopurine, or theophylline.
Pediatric Use: Safety and effectiveness in pediatric patients under 18 years of age have not been established
Febustat was studied in healthy subjects in doses up to 300 mg daily for seven days without evidence of dose-limiting toxicities.
Keep out of the reach of children. Keep in a cool & dry place, protected from light.
Fbt Tablet price in India 119