Alfunol contains Alfuzosin Hydrochloride. Alfunol uses:
Alfunol is indicated for the treatment of the signs and symptoms of benign prostatic hyperplasia(BPH), lower urinary tract symptoms (LUTS) including urinary frequency, nocturia, incomplete emptying and urinary hesitancy associated with BPH.
|Therapeutic Class:||Alpha adrenoceptor blocking drugs|
|Manufacturer:||KNOLL HEALTHCARE PVT LTD|
|Last Updated:||2020-11-21 18:15:00|
Alfunol contains Alfuzosin Hydrochloride 10.0 Mg. Alfunol doses
The recommended dosage is one 10 mg Alfunol tablet daily to be taken immediately after the same meal each day. The tablets should not be chewed or crushed.
Alfunol tablet should be swallowed whole.
This formulation is generally well tolerated. However the following adverse events have been reported include abdominal pain, dyspepsia, constipation, nausea, impotence, bronchitis, sinusitis and pharyngitis.
Alfunol is a selective antagonist of post-synaptic a1 adrenoreceptors, which are located in the prostate, bladder base, bladder neck, prostatic capsule, and prostatic urethra. Alfunol relaxes the tone of the prostate smooth muscle, prostate capsule, bladder neck and proximal urethra. It competitively and selectively binds to the post synaptic a1-adrenergic receptors in the lower urinary tract. It also relaxes sympathetic nervous stimulation, reduces resting urethral pressure and inhibits urethral hypertonia-induced sympathetic nervous stimulation. As an uroselective agent, Alfunol preferentially binds to prostatic a1 receptors, blockage of these receptors result in reduction of BPH symptoms, improvement of urine flow and decreased potential for hypertensive events.
Alfunol should not be given to patients with moderate or severe hepatic insufficiency. Caution should be exercised when Alfuzosin is administered in patients with severe renal insufficiency. If symptoms of angina pectoris should newly appear or worsen, Alfunol should be discontinued.
Alfuzosin may interact with other alpha-blockers, Atenolol, Cimetidine, Diltiazem, Ketoconazole and Ritonavir.
Alfunol is not indicated for use in pregnant and lactating mother.
Alfunol tablet is contraindicated for hypersensitivity to Alfunol, history of orthostatic hypotension, combination with other alpha-1 receptor blockers, hepatic insufficiency.
Efficacy of Alfunol has not been demonstrated in children aged 2 to 16 years. Therefore Alfunol is not indicated for use in the paediatric population.
Overdose of Alfunol should lead to hypotension; support of the cardiovascular system is of first importance. Restoration of blood pressure and normalization of heart rate may be accomplished by keeping the patient in the supine position. If this measure is inadequate, then the administration of intravenous fluids should be considered. If necessary, vasopressors should then be used, and the renal function should be monitored and supported as needed.
Store in a cool and dry place, protected from light
Alfunol Tablet price in India 131.75