Olopatadine Hydrochloride (Eye Drops)

Olopatadine Hydrochloride (Eye Drops) Uses

Olopatadine is indicated for the treatment of ocular itching associated with allergic conjunctivitis.

Olopatadine Hydrochloride (Eye Drops) Generic

Olopatadine Hydrochloride (Eye Drops)

Olopatadine Hydrochloride (Eye Drops) Introduction

Olopatadine is an inhibitor of the release of histamine from the mast cell and a relatively selective histamine H1‐antagonist that inhibits the in vivo and in vitro type 1 immediate hypersensitivity reaction including inhibition of histamine induced effects on human conjunctival epithelial cells. Olopatadine is devoid of effects on alpha adrenergic, dopamine and muscarinic type 1 and 2 receptors. Following topical ocular administration in human, olopatadine was shown to have low systemic exposure.

Olopatadine Hydrochloride (Eye Drops) Therapeutic Class

Ophthalmic Non-Steroid drugs

Olopatadine Hydrochloride (Eye Drops) Doses

0.1% Sterile Eye Drops: One drop in each affected eye two times per day at an interval of 6 to 8 hours. 

0.2% Sterile Eye Drops: One drop in the affected eye once a day.

0.7% Sterile Eye Drops: One drop in each affected eye once a day.

Olopatadine Hydrochloride (Eye Drops) Administrations

Olopatadine Hydrochloride (Eye Drops) Side Effects

Headaches have been reported at an incidence of 7%. The following adverse experiences have been reported in less than 5% of patients: Asthenia, blurred vision, burning or stinging, cold syndrome, dry eye, foreign body sensation, hyperemia, hypersensitivity, keratitis, lid edema, nausea, pharyngitis, pruritus, rhinitis, sinusitis, and taste perversion

Olopatadine Hydrochloride (Eye Drops) Precaution

Olopatadine HCl ophthalmic solution should not be used to treat contact lens related irritation. Patients who wear soft contact lenses should be instructed to wait at least ten minutes after instilling Olopatadine Hydrochloride ophthalmic solution before they insert their contact lenses.

Olopatadine Hydrochloride (Eye Drops) Interaction

May result in additive CNS depression with CNS depressants.

Olopatadine Hydrochloride (Eye Drops) Uses During Pregnancy

There are no adequate and well controlled studies in pregnant women. Because animal studies are not always predictive of human responses, this drug should be used in pregnant women only if the potential benefit to the mother justifies the potential risk to the fetus.

It is not known whether topical ocular administration could result in sufficient systemic absorption to produce detectable quantities in the human breast milk. Nevertheless, caution should be exercised when Olopatadine Hydrochloride ophthalmic solution is administered to a nursing mother.

Olopatadine Hydrochloride (Eye Drops) Accute Overdose

Symptoms: Drowsiness in adults and, initially, agitation and restlessness, followed by drowsiness in childn. 

Management: Symptomatic or supportive treatment.

Olopatadine Hydrochloride (Eye Drops) Contraindication

Olopatadine Hydrochloride ophthalmic solution is contraindicated in persons with a known hypersensitivity to Olopatadine Hydrochloride.

Olopatadine Hydrochloride (Eye Drops) Uses Direction

 

Olopatadine Hydrochloride (Eye Drops) Storage Condition

Store below 30° C in a cool and dry place protected from light. Keep out of reach of children. Do not touch the dropper tip to surfaces since this may contaminate the solution. Do not use after 30 days of first opening.

Olopatadine Hydrochloride (Eye Drops) Special Warning

Geriatric Use: No overall differences in safety or effectiveness have been observed betweents.

Olopatadine Hydrochloride (Eye Drops) Interactions with other Medicine

 

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