Cetirizine Dihydrochloride

Cetirizine Dihydrochloride Uses

Cetirizine is indicated for the treatment of seasonal allergic rhinitis and conjunctivitis, perennial allergic rhinitis, pruritus and urticaria. It is also used in allergen induced asthma.

Cetirizine Dihydrochloride Generic

Cetirizine Dihydrochloride

Cetirizine Dihydrochloride Introduction

Cetirizine is a potent and highly selective antagonist of the peripheral histamine H1-receptor on effector cells in the GI tract, blood vessels and respiratory tract.

Cetirizine Dihydrochloride Therapeutic Class

Sedating Anti-histamine

Cetirizine Dihydrochloride Doses

Tablet:

  • Adults and children over 6 years: 1 tablet (10 mg) once daily or ½ tablet twice daily.
  • Children 2-6 years: ½ tablet once daily.

Syrup:

  • Adults and children over 6 years: 2 teaspoonful (10 mg) once daily or 1 teaspoon (5 mg) twice daily.
  • Children 2-6 years: 1 teaspoonful once daily or ½ teaspoon twice daily.

Cetirizine Dihydrochloride Administrations

Cetirizine Dihydrochloride Side Effects

Cetirizine dihydrochloride is well tolerated. Lower incidence of sedation, headache, dry mouth, and gastrointestinal disturbances may occur. It does not produce anticholinergic effects.

Cetirizine Dihydrochloride Precaution

Caution should be exercised when driving a car or operating a heavy machinery. Concurrent use of cetirizine with alcohol or other CNS depressants should be avoided because additional reduction in alertness and CNS performance may occur.

Cetirizine Dihydrochloride Interaction

No clinically significant drug interactions have been found with theophylline, azithromycin, pseudoephedrine, ketoconazole or erythromycin and with some other drugs.

Cetirizine Dihydrochloride Uses During Pregnancy

Pregnancy category B. There are no adequate and well controlled studies in pregnant women. Cetirizine should be used during pregnancy only if clearly needed. Cetirizine has been reported to be excreted in human breast milk. As large amount of drugs are excreted in human milk, use of Cetirizine in nursing mother is not recommended.

Cetirizine Dihydrochloride Accute Overdose

Symptoms: Confusion, dizziness, fatigue, headache, malaise, restlessness, sedation, somnolence, diarrhoea, mydriasis, pruritus, stupor, tachycardia, tremor, and urinary retention. 

Management: Symptomatic and supportive treatment. Gastric lavage may be done shortly following ingestion.

Cetirizine Dihydrochloride Contraindication

Cetirizine Dihydrochloride is contraindicated in those patients with a known hypersensitivity to it or any of its ingredients or hydroxyzine.

Cetirizine Dihydrochloride Uses Direction

 

Cetirizine Dihydrochloride Storage Condition

Store between 20-25°C. Syrup: Store between 2-8°C.

Cetirizine Dihydrochloride Special Warning

 

Cetirizine Dihydrochloride Interactions with other Medicine

 

Drugs from this generic