গ্যাফিসেন্ট ব্যবহারে কি কি সতর্কতা অবলম্বন করা উচিত?

জিজ্ঞাসার সময় 

Bissoy Curator

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এই উত্তরটি Gefitinib জেনেরিক এর অন্তর্ভুক্ত Geficent এর জন্য প্রযোজ্য।

গ্যাফিসেন্ট ব্যবহারে সতর্কতা

Interstitial lung disease (ILD): ILD occurred in patients taking Gefitinib. Gefitinib should be withheld for worsening of respiratory symptoms. It should be discontinued if ILD is confirmed.

Hepatotoxicity: Periodic liver function testing should be performed. Gefitinib should be withheld for Grade 2 or higher for ALT and/or AST elevations. It should be discontinued for severe hepatic impairment.

Gastrointestinal perforation: Gefitinib should be discontinued for gastrointestinal perforation. 

Diarrhea: Gefitinib should be withheld for Grade 3 or higher diarrhea.Ocular Disorders including Keratitis: Gefitinib should be withheld for signs and symptoms of severe or worsening ocular disorders including keratitis. It should be discontinued for persistent ulcerative keratitis.Bullous and Exfoliative Skin Disorders: Gefitinib should be withheld for Grade 3 or higher skin reactions or exfoliative conditions.

Embryo-fetal Toxicity: Gefitinib can cause fetal harm. Potential risk of Gefitinib to a fetus should be advised and effective contraception should be used.