Zovibact, a brand name for a formulation containing essential Aciclovir, is widely used for various health benefits. This guide provides comprehensive information on the uses, dosage, side effects, and mechanism of action of Zovibact, as well as insights into how long it takes to work. Understanding these aspects can help you make informed decisions about its use and effectiveness.

Zovibact Introduction

Zovibact, also known as Acyclovir, is an antiviral medication used to treat a variety of herpes-related infections, such as shingles, genital herpes, and chickenpox. It is an oral medication available in both tablet and oral suspension form. It is also available in topical cream form.

Uses for Zovibact

Zovibact is used to treat and prevent infections such as herpes simplex virus (HSV)1 and 2, chickenpox, and shingles. It is used to reduce pain and heal sores caused by these infections. It can also help to prevent the spread of the infections.

Mechanism of Action

Zovibact works by stopping the virus from making more copies of itself. It does this by stopping the activity of an enzyme the virus needs to replicate. This stops the virus from spreading, and ultimately helps it to clear up.

How Long Does It Take to Work?

Zovibact may take up to 2 days for the viral shedding to reduce. It is important to note that the virus can still be passed on during this time. For the best results, Zovibact should be taken for the full course of treatment, which can be up to 5 days.


Zovibact is rapidly and almost completely absorbed from the gastrointestinal tract. It is approximately 20% bio available, which means it should be taken with food or milk to enhance its absorption.

Route of Elimination

Zovibact is eliminated via the kidneys, primarily as unchanged (or active) drug. Approximately 20–30% will be eliminated in the urine as inactive metabolites.


Dosage of Zovibact will depend on the type of infection being treated. The usual adult dosage for herpes simplex virus infections is 200-400 mg by mouth 5 times daily, up to five days. For genital herpes, the dosage is 200mg every 4 hours (6 doses per day), up to five days. For shingles, the dosage is 800mg five times per day for 7-10 days.


Zovibact can be taken with or without food. It is important to take it regularly and exactly as your doctor prescribes. Do not stop taking it, even if you feel better, unless your doctor tells you to.

Side Effect

Common side effects of Zovibact include nausea, stomach pain, headache, dizziness, and feeling tired. Some patients may experience an allergic reaction such as hives or difficulty breathing, which should be reported to their healthcare provider immediately.


Zovibact has a low risk of toxicity when taken as directed and following your healthcare provider's instructions. The most common adverse reactions are gastrointestinal disturbances such nausea, vomiting, and diarrhea.


Patients with kidney or liver disease should use Zovibact with caution. Zovibact should not be taken during pregnancy, unless prescribed by a healthcare provider. Before taking Zovibact, it's important to let your healthcare provider know if you have any allergies, sensitivities, or other health conditions.


Zovibact may interact with other medications such as probenecid, tubocurarine, certain antibiotics, and some antacids. It's important to tell your healthcare provider if you are taking other medications or supplements.

Disease Interaction

Patients with a compromised immune system, such as those with HIV, and those with kidney or liver disease, should use Zovibact with caution as it can cause more serious side effects. It is also important for these patients to follow their healthcare provider’s instructions.

Drug Interactions

Zovibact may interact with medications such as probenecid, tubocurarine, certain antibiotics, and some antacids. Tell your doctor if you are taking any other medications or supplements.

Food Interactions

Zovibact should be taken with food or milk to enhance its absorption. Its effectiveness can also be decreased if taken with certain foods.

Pregnancy Use

Zovibact should not be taken during pregnancy, unless prescribed by a healthcare provider. It can pass into breast milk, so it should not be taken by breastfeeding mothers.

Lactation Use

Zovibact should not be used by breastfeeding mothers. It can pass into breast milk and can harm a nursing baby.

Acute Overdose

An overdose of Zovibact may lead to severe and even life-threatening side effects. It is important to contact your healthcare provider or local poison control center as soon as possible if you think you may have taken too much Zovibact.


Zovibact is contraindicated in patients who are allergic or hypersensitive to it. It is also contraindicated in patients with renal impairment or severe hepatic impairment.

Use Direction

It is important to follow the instructions of your healthcare provider when taking Zovibact. Do not take more or less medication than prescribed or discontinue taking the medication abruptly without consulting your healthcare provider.

Storage Condition

Store Zovibact tablets at room temperature away from moisture and heat. Keep the suspension form in the fridge (but not in the freezer).

Volume of Distribution

The volume of distribution is 0.2-1L/kg for Zovibact.

Half Life

The average half life is 2.0 to 4.7 hours for Zovibact.


The average clearance of Zovibact is 0.1 L/hr/kg.

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